Senkopta Nadir Tanı: Tip 2 Brugada Sendromu / A Rare Diagnosis of Syncope: Type 2 Brugada Syndrome

Yıl 2021, Cilt: 2 Sayı: 2, 35 - 36, 11.10.2021

Sertaç Güler Dilber Üçöz Kocaşaban

Öz

Brugada syndrome (BS) is an autosomal-dominant inherited genetic disorder characterized by mutations in cardiac sodium-channel genes, characteristic changes in electrocardiography (ECG) and associated with increased risk of ventricular arrhythmia and sudden cardiac death. BS mostly affects Asian races and its prevalence varies in different societies. Although it is a rare disease, it should be considered in patients admitted to the emergency department (ED) with the complaint of syncope. In a study, it was revealed that the main complaint in 28% of patients with BS was syncope. Here, we present a 19-year-old male patient who admitted to ED with the complaint of syncope and was diagnosed with BS.

Anahtar Kelimeler

Brugada sydrome, emergency medicine, sudden cardiac death, syncope

Destekleyen Kurum

yok

Kaynakça

• 1. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 1992;20:1391-6.
• 2. Brugada J, Brugada P. What to do in patients with no structural heart disease and sudden arrhythmic death? Am J Cardiol 1996;78:69-75.
• 3. Alings M, Wilde A. "Brugada" syndrome: clinical data and suggested pathophysiological mechanism. Circulation 1999;99:666-73.
• 4. Miyasaka Y, Tsuji H, Yamada K, Tokunaga S, Saito D, Imuro Y, et al. Prevalence and mortality of the Brugada-type electrocardiogram in one city in Japan. J Am Coll Cardiol 2001;38:771-4.
• 5. Matsuo K, Akahoshi M, Nakashima E, Seto S, Yano K. Clinical characteristics of subjects with the Brugada-type electrocardiogram:. J Cardiovasc Electrophysiol 2004;15:653-7.
• 6. Patel SS, Anees S, Ferrick KJ. Prevalence of a Brugada pattern electrocardiogram in an urban population in the United States. Pacing Clin Electrophysiol 2009;32:704-8.
• 7. Sacher F, Arsac F, Wilton SB, Derval N, Denis A, de Guillebon M, et al. Syncope in Brugada syndrome patients: prevalence, characteristics, and outcome. Heart Rhythm 2012;9:1272-9.
• 8. Benito B, Sarkozy A, Mont L, Henkens S, Berruezo A, Tamborero D, et al. Gender differen-ces in clinical manifestations of Brugada syndrome. J Am Coll Cardiol 2008;52:1567-73.
• 9. Brugada J, Brugada R, Brugada P. Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest. Circu-lation 2003;108:3092-6.
• 10. Rodríguez-Mañero M, Namdar M, Sarkozy A, Casado-Arroyo R, Ricciardi D, de Asmundis C, et al. Prevalence, clinical characteristics and management of atrial fibrillation in patients with Brugada syndrome. Am J Cardiol 2013;111:362-7.
• 11. Priori SG, Wilde AA, Horie M, Cho Y, Behr ER, Berul C, et al. HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013. Heart Rhythm 2013;10:1932-63.