Köpeklerde Kornea Yaralarının Onarımında Organik Doku Yapıştırıcısı Fibrin Adeziv'in Etkileri

Öz

Organik doku yapıştırıcısı Fibrin Adeziv’in köpek korneal yara iyileşmesi üzerine etkisi araştırıldı. Köpek modelinde oluşturulan 2, 5, 7, 11 mm uzunluğundaki kesiler üzerine 0.02-0.05 ml Fibrin Adeziv uygulandı. Kontrol gruplarında konjunktival flap, dikiş, kontakt lens ve tarsorafi uygulamaları yapıldı. Korneal yara iyileşmesinin 2 aylık izleme süresince klinik, bu süre sonunda histolojik özellikleri araştırıldı. Fibrin Adeziv’in basit dikiş uygulanan kesilerle benzer özellikte yara iyileşmesi sağladığı belirlendi. Fibrin Adeziv’in dikiş konulamayan olgularda dikiş uygulamalarına alternatif oluşturabileceği saptandı. 

Anahtar Kelimeler

• Fibrin Adeziv, Korneal yara iyileşmesi, Köpek.

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Öz

The effects of Fibrin Adhesive (Tisseel-tissue adhesive) in corneal wounds were investigated in dogs. A 0.02-0.05 ml Tisseel was applied onto the incision area (2, 5, 7, 11 mm length) in dog model. Conjunctival flapping, suture applications, contact lens placement and tharsorraphy were performed in the control groups. To evaluate the corneal wound healing, the clinical controls were conducted during 2 months and after this period histological examinations were carried out. It was detected that the corneal wound healing with Tisseel was similar with simple suture pattern. It was determined that Tisseel could be an alternative method in cases not suitable for sutures.

Anahtar Kelimeler

• Corneal Wound Healing, Dog, Fibrin Adhesive.

Kaynakça

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