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Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats

Yıl 2007, Cilt: 2 Sayı: 3, 0 - , 07.09.2015

Ali Karadeniz Abdulkadir Yıldırım Fikret Çelebi

Öz

This study was designed to investigate the protective effects of Panax ginseng against acute brain damage induced by CCl4 in rats. A total of 30 healthy female Sprague–Dawley rats were divided in to three groups. Sedentary control group (group C) injected intraperitoneally (i.p.) with physiological saline as placebo for 7 consecutive days. CCl4 toxication group was injected by i.p. a single dose of CCl4 (group CCl4). Panax ginseng plus CCl4 group (200 mg/kg) was feeding through an orogastric tube for 7 consecutive days prior to CCl4 injection (group CCl4 + PG). The degree of protection in brain tissue was evaluated by the levels of malondialdehyde (MDA), glutathione (GSH), superoxide dismutase (SOD), glutathione peroxidase (GPx) and nitric oxide (NO). Panax ginseng showed a significant brain-protective effect by decreasing the level of lipid peroxidation (MDA) and elevated the activities of GSH and SOD (p<0.05). Consequently Panax ginseng was blocked oxidative brain damage induced by CCl4 in rats

Anahtar Kelimeler

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Yıl 2007, Cilt: 2 Sayı: 3, 0 - , 07.09.2015

Ali Karadeniz Abdulkadir Yıldırım Fikret Çelebi

Öz

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Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makaleleri
Yazarlar

Ali Karadeniz Bu kişi benim

Abdulkadir Yıldırım Bu kişi benim

Fikret Çelebi Bu kişi benim

Yayımlanma Tarihi 7 Eylül 2015
Yayımlandığı Sayı Yıl 2007 Cilt: 2 Sayı: 3

Kaynak Göster

APA Karadeniz, A., Yıldırım, A., & Çelebi, F. (2015). Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 2(3).
AMA Karadeniz A, Yıldırım A, Çelebi F. Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. Eylül 2015;2(3).
Chicago Karadeniz, Ali, Abdulkadir Yıldırım, ve Fikret Çelebi. “Protective Effect of Panax Ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 2, sy. 3 (Eylül 2015).
EndNote Karadeniz A, Yıldırım A, Çelebi F (01 Eylül 2015) Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 2 3
IEEE A. Karadeniz, A. Yıldırım, ve F. Çelebi, “Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”, Atatürk Üniversitesi Veteriner Bilimleri Dergisi, c. 2, sy. 3, 2015.
ISNAD Karadeniz, Ali vd. “Protective Effect of Panax Ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 2/3 (Eylül 2015).
JAMA Karadeniz A, Yıldırım A, Çelebi F. Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2015;2.
MLA Karadeniz, Ali vd. “Protective Effect of Panax Ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, c. 2, sy. 3, 2015.
Vancouver Karadeniz A, Yıldırım A, Çelebi F. Protective Effect of Panax ginseng Against Carbon Tetrachloride (CCl4) - Induced Oxidative Brain Injury in Rats. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2015;2(3).