BibTex RIS Kaynak Göster

Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi

Yıl 2012, Cilt: 7 Sayı: 2, 77 - 84, 01.10.2012

Barış Uslu , Dide Kılıçalp Kılıç Fetih Gülyüz Yeter Değer , Ömer Uçar

Öz

Bu çalışmada, rutin kullanımdaki mobil telefondan yayılan 900 MHz’lik elektromanyetik alana (EMA) 60 gün süreyle
maruz kalan erkek Gine domuzlarında testis ağırlığı ve epididimal sperm kalitesi araştırıldı. Oniki adet sağlıklı erkek kobay
rastgele uygulama, EMA (n=6) ve kontrol, K (n=6) grubu olarak iki gruba ayrıldı. Uygulama grubu (Grup EMA), 60 gün süre ile
her gün mobil bir telefonla yayılan (telefonu 20 dk çaldırma/konuşma modu, 23 saat 40 dk uyku/standby modu) 900 MHz’lik
EMA’a (217 Hz pulse rate, 2 W maximum peak power, SAR 0.95 w/kg) maruz bırakıldı. Kontrol grubu (Grup K) benzer şartlar
altında tutuldu, ancak radyasyona maruz bırakılmadı. Grup EMA ve K arasında, sırasıyla, testis ağırlığı (3.6 g ve 4.4 g),
epididimal sperm motilitesi (%61.7 ve %70.0) ve anormal sperm oranı (%5.8 ve %3.7) bakımından anlamlı farklılıklar
gözlenmedi (P>0.05). Bununla birlikte, Grup EMA’deki sperm sayısı (549.6 x 106 sperm/ml) Grup K’dekilerden (799.17 x 106
sperm/ml) önemli düzeyde (P

Anahtar Kelimeler

Elektromanyetik dalga Kobay Sperm Testis

Kaynakça

  • Agarwal A., 2007. Cell phones and male infertility: dissecting the relationship. Reprod. Biomed., 15, 266-270.
  • Agarwal A., Deepinder F., Sharma RK., Ranga G., Li J., 2008. Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study. Fertil. Steril., 89, 124-128.
  • Aitken R., Bennetts L., Sawyer D., Wiklendt A., King B., 2005. Impact of radiofrequency electromagnetic radiation on DNA integrity in the male germline. Int. J. Androl., 28, 171-179.
  • Atessahin A., Karahan I., Turk G., Gur S., Yilmaz S., Ceribasi AO., 2006. Protective role of lycopene on cisplatin- induced changes in sperm characteristics, testicular damage and lipid peroxidation in rats. Reprod. Toxi- col., 21, 42-47.
  • Dasdag S., Ketani MA., Akdag Z., Ersay AR., Sari I., Demirtas OC., Celik MS., 1999. Whole body micro- wave exposure emitted by cellular phones and tes- ticular function of rats. Urol. Res., 27, 219-223.
  • Dasdag S., Akdag MZ., Aksen F., Yilmaz F., Bashan M., Dasdag M., Celik MS., 2003a. Whole body exposure of rats to microwaves emitted from a cell phone does not affect the testes. Bioelectromagnetics, 24, 182-188.
  • Dasdag S., Akdag MZ., Ulukaya E., Uzunlar AK., Yegin D., 2003b. Mobile phone exposure does not induce apoptosis on spermatogenesis in rats. Arch. Med. Res., 39, 40-44.
  • Davoudi M., Brossner C., Kuber W., 2002. The influence of electromagnetic waves on sperm motility. J. Urol., 19, 18-22.
  • Ergün G., Aktaş S., 2009. ANOVA modellerinde kareler toplamı yöntemlerinin karşılaştırılması. Kafkas Üniv. Vet. Fak. Derg., 15, 481-484.
  • Erogul O., Oztas E., Yildirim I., Kir T., Aydur E., Komesli G., Irkilata HC., Irmak MK., Peker AF., 2006. Effects of electromagnetic radiation from a cellular phone on human sperm motility: An in vitro study. Arch. Med. Res., 37, 840-843.
  • Fejes I., Zaivaczki Z., Szallosi J., Koloszair S., Daru J., Kovaics L., Pail A., 2005. Is there a relationship be- tween cell phone use and semen quality? Arch. An- drol., 51, 385-393.
  • Fitzsimmons RJ., Strong DD., Mohan S., Baylink DJ., 1992. Low-amplitude, low-frequency electricity field- stimulated bone cell proliferation may in part be mediated by increased IGF-II release. J. Cell. Physiol., 150, 84-89.
  • Goodman R., Henderson AS., 1988. Exposure of salivary gland cells to low-frequency electromagnetic fields alters polypeptide synthesis. Proc. Natl. Acad. Sci. USA., 85, 3928-3932.
  • Jones R., Mann T., Sherins R., 1979. Peroxidative breakdown of phospholipids in human spermato- zoa: spermicidal effects of fatty acid peroxides and protective action of seminal plasma. Fertil. Steril., 31, 531-537.
  • Kilgallon SJ., Simmons LW., 2005. Image content influences men’s semen quality. Biol. Lett., 1, 253- 255.
  • Koppers AJ., De Iuliis GN., Finnie JM., McLaughlin EA., Aitken RJ., 2008. Significance of mitochondrial reac- tive oxygen species in the generation of oxidative stress in spermatozoa. J. Clin. Endocrinol. Metab., 93, 3199-3207.
  • Kundi M., Mild K., Hardell L., Mattsson MO., 2004. Mobile telephones and cancer- a review of epidemiological evidence. J. Toxicol. Environ. Health. B. Crit. Rev., 7, 351-384.
  • Lahkola A., Salminen T., Raitanen J., Heinavaara S., Schoemaker MJ., Christensen HC., Feychting M., Johansen C., Klaeboe L., Lonn S., Swerdlow AJ., Tynes T., Auvinen A., 2008. Meningioma and mobile phone use- a collaborative case-control study in five North European countries. Int. J. Epidemiol., 37, 1304-1313.
  • Mashevich M., Folkman D., Kesar A., Barbul A., Korenstein R., Jerby E., Avivi L., 2003. Exposure of human pe- ripheral blood lymphocytes to electromagnetic fields associated with cellular phones leads to chro- mosomal instability. Bioelectromagnetics, 24, 82-90.
  • Minitab, 1996. Version 11.2. MINITAB Inc., Pennsylvania, USA.
  • Odeigah PGC., 1997. Sperm-head abnormalities and dominant lethal effects of formaldehyde in albino rats. Mutat. Res., 389, 141-148.
  • Otitoloju AA., Obe IA., Adewale OA., Otubanjo OA., Osunkalu VO., 2010. Preliminary study on the induc- tion of sperm head abnormalities in mice, mus mus- culus, exposed to radiofrequency radiations from global system for mobile communication base sta- tions. Bull. Environ. Contam. Toxicol., 84, 51-54.
  • Otubanjo OA., Mosuro AA., 2001. An in vivo evaluation of induction of abnormal sperm morphology by some anthelminthic drugs in mice. Mutat. Res., 497, 131- 138.
  • Ozguner M., Koyu A., Cesur G., Ural M., Ozguner F., Gokcimen A., Delibas N., 2005. Biological and mor- phological effects on the reproductive organ of rats after exposure to electromagnetic field. Saudi. Med. J., 26, 405-410.
  • Ozguner F., Bardak Y., Comlekci S., 2006. Protective effects of melatonin and caffeic acid phenethyl ester against retinal oxidative stress in long-term use of mobile phone: a comparative study. Mol. Cell. Bio- chem., 282, 83-88.
  • Pacini S., Ruggiero M., Sardi I., Aterini S., Gulisano F., Gulisano M., 2002. Exposure to global system for mobile communication (GSM) cellular phone radiof- requency alters gene expression, proliferation, and morphology of human skin fibroblasts. Oncol. Res., 13, 19-24.
  • Ribeiro EP., Rhoden EL., Horn MM., Rhoden C., Lima LP., Toniolo L., 2007. Effects of subchronic exposure to radio frequency from a conventional cellular tele- phone on testicular function in adult rats. J. Urol., 177, 395-399.
  • Saunders RD., Kowalczuk CI., 1981. Effects of 2.45 GHz microwave radiation and heat on mouse spermato- genic epithelium. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med., 40, 623-632.
  • Sharlip ID., Jarow JP., Belker AM., Lipshultz LI., Sigman M., Thomas AJ., Schlegel PN., Howards SS., Nehra A., Damewood MD., Overstreet JW., Sadovsky R., 2002. Best practice policies for male infertility. Fertil. Steril., 77, 873-882.
  • Shen H., Ong C., 2000. Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility. Free. Radic. Biol. Med., 15, 529-536.
  • Sonmez M., Turk G., Yuce A., 2005. The effect of ascorbic acid supplementation on sperm quality, lipid per- oxidation and testosterone levels of male Wistar rats. Theriogenology, 63, 2063-2072.
  • Sykes PJ., McCallum BD., Bangay MJ., Hooker AM., Morley AA., 2001. Effect of exposure to 900 MHz radiofre- quency radiation on intrachromosomal recombina- tion in pKZ1 mice. Radiat. Res., 156, 495-502.
  • Thonneau P., Bujan L., Multigner L., Mieusset R., 1998. Occupational heat exposure and male fertility: a review. Human. Reprod., 13, 2122-2125.
  • Tice RR., Hook GG., Donner M., McRee DI., Guy AW., 2002. Genotoxicity of radiofrequency signals. I. In- vestigation of DNA damage and micronuclei induc- tion in cultured human blood cells. Bioelectromag- netics, 23, 113-126.
  • Yan JG., Agresti M., Bruce T., Yan YH., Granlund A., Matloub HS., 2007. Effects of cellular phone emis- sions on sperm motility in rats. Fertil. Steril., 88, 957-964.
  • Yokoi K., Uthus EO., Nielsen FH., 2003. Nickel deficiency diminishes sperm quantity and movement in rats. Biol. Trace. Elem. Res., 93, 141-153.

Yıl 2012, Cilt: 7 Sayı: 2, 77 - 84, 01.10.2012

Barış Uslu , Dide Kılıçalp Kılıç Fetih Gülyüz Yeter Değer , Ömer Uçar

Öz

Kaynakça

  • Agarwal A., 2007. Cell phones and male infertility: dissecting the relationship. Reprod. Biomed., 15, 266-270.
  • Agarwal A., Deepinder F., Sharma RK., Ranga G., Li J., 2008. Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study. Fertil. Steril., 89, 124-128.
  • Aitken R., Bennetts L., Sawyer D., Wiklendt A., King B., 2005. Impact of radiofrequency electromagnetic radiation on DNA integrity in the male germline. Int. J. Androl., 28, 171-179.
  • Atessahin A., Karahan I., Turk G., Gur S., Yilmaz S., Ceribasi AO., 2006. Protective role of lycopene on cisplatin- induced changes in sperm characteristics, testicular damage and lipid peroxidation in rats. Reprod. Toxi- col., 21, 42-47.
  • Dasdag S., Ketani MA., Akdag Z., Ersay AR., Sari I., Demirtas OC., Celik MS., 1999. Whole body micro- wave exposure emitted by cellular phones and tes- ticular function of rats. Urol. Res., 27, 219-223.
  • Dasdag S., Akdag MZ., Aksen F., Yilmaz F., Bashan M., Dasdag M., Celik MS., 2003a. Whole body exposure of rats to microwaves emitted from a cell phone does not affect the testes. Bioelectromagnetics, 24, 182-188.
  • Dasdag S., Akdag MZ., Ulukaya E., Uzunlar AK., Yegin D., 2003b. Mobile phone exposure does not induce apoptosis on spermatogenesis in rats. Arch. Med. Res., 39, 40-44.
  • Davoudi M., Brossner C., Kuber W., 2002. The influence of electromagnetic waves on sperm motility. J. Urol., 19, 18-22.
  • Ergün G., Aktaş S., 2009. ANOVA modellerinde kareler toplamı yöntemlerinin karşılaştırılması. Kafkas Üniv. Vet. Fak. Derg., 15, 481-484.
  • Erogul O., Oztas E., Yildirim I., Kir T., Aydur E., Komesli G., Irkilata HC., Irmak MK., Peker AF., 2006. Effects of electromagnetic radiation from a cellular phone on human sperm motility: An in vitro study. Arch. Med. Res., 37, 840-843.
  • Fejes I., Zaivaczki Z., Szallosi J., Koloszair S., Daru J., Kovaics L., Pail A., 2005. Is there a relationship be- tween cell phone use and semen quality? Arch. An- drol., 51, 385-393.
  • Fitzsimmons RJ., Strong DD., Mohan S., Baylink DJ., 1992. Low-amplitude, low-frequency electricity field- stimulated bone cell proliferation may in part be mediated by increased IGF-II release. J. Cell. Physiol., 150, 84-89.
  • Goodman R., Henderson AS., 1988. Exposure of salivary gland cells to low-frequency electromagnetic fields alters polypeptide synthesis. Proc. Natl. Acad. Sci. USA., 85, 3928-3932.
  • Jones R., Mann T., Sherins R., 1979. Peroxidative breakdown of phospholipids in human spermato- zoa: spermicidal effects of fatty acid peroxides and protective action of seminal plasma. Fertil. Steril., 31, 531-537.
  • Kilgallon SJ., Simmons LW., 2005. Image content influences men’s semen quality. Biol. Lett., 1, 253- 255.
  • Koppers AJ., De Iuliis GN., Finnie JM., McLaughlin EA., Aitken RJ., 2008. Significance of mitochondrial reac- tive oxygen species in the generation of oxidative stress in spermatozoa. J. Clin. Endocrinol. Metab., 93, 3199-3207.
  • Kundi M., Mild K., Hardell L., Mattsson MO., 2004. Mobile telephones and cancer- a review of epidemiological evidence. J. Toxicol. Environ. Health. B. Crit. Rev., 7, 351-384.
  • Lahkola A., Salminen T., Raitanen J., Heinavaara S., Schoemaker MJ., Christensen HC., Feychting M., Johansen C., Klaeboe L., Lonn S., Swerdlow AJ., Tynes T., Auvinen A., 2008. Meningioma and mobile phone use- a collaborative case-control study in five North European countries. Int. J. Epidemiol., 37, 1304-1313.
  • Mashevich M., Folkman D., Kesar A., Barbul A., Korenstein R., Jerby E., Avivi L., 2003. Exposure of human pe- ripheral blood lymphocytes to electromagnetic fields associated with cellular phones leads to chro- mosomal instability. Bioelectromagnetics, 24, 82-90.
  • Minitab, 1996. Version 11.2. MINITAB Inc., Pennsylvania, USA.
  • Odeigah PGC., 1997. Sperm-head abnormalities and dominant lethal effects of formaldehyde in albino rats. Mutat. Res., 389, 141-148.
  • Otitoloju AA., Obe IA., Adewale OA., Otubanjo OA., Osunkalu VO., 2010. Preliminary study on the induc- tion of sperm head abnormalities in mice, mus mus- culus, exposed to radiofrequency radiations from global system for mobile communication base sta- tions. Bull. Environ. Contam. Toxicol., 84, 51-54.
  • Otubanjo OA., Mosuro AA., 2001. An in vivo evaluation of induction of abnormal sperm morphology by some anthelminthic drugs in mice. Mutat. Res., 497, 131- 138.
  • Ozguner M., Koyu A., Cesur G., Ural M., Ozguner F., Gokcimen A., Delibas N., 2005. Biological and mor- phological effects on the reproductive organ of rats after exposure to electromagnetic field. Saudi. Med. J., 26, 405-410.
  • Ozguner F., Bardak Y., Comlekci S., 2006. Protective effects of melatonin and caffeic acid phenethyl ester against retinal oxidative stress in long-term use of mobile phone: a comparative study. Mol. Cell. Bio- chem., 282, 83-88.
  • Pacini S., Ruggiero M., Sardi I., Aterini S., Gulisano F., Gulisano M., 2002. Exposure to global system for mobile communication (GSM) cellular phone radiof- requency alters gene expression, proliferation, and morphology of human skin fibroblasts. Oncol. Res., 13, 19-24.
  • Ribeiro EP., Rhoden EL., Horn MM., Rhoden C., Lima LP., Toniolo L., 2007. Effects of subchronic exposure to radio frequency from a conventional cellular tele- phone on testicular function in adult rats. J. Urol., 177, 395-399.
  • Saunders RD., Kowalczuk CI., 1981. Effects of 2.45 GHz microwave radiation and heat on mouse spermato- genic epithelium. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med., 40, 623-632.
  • Sharlip ID., Jarow JP., Belker AM., Lipshultz LI., Sigman M., Thomas AJ., Schlegel PN., Howards SS., Nehra A., Damewood MD., Overstreet JW., Sadovsky R., 2002. Best practice policies for male infertility. Fertil. Steril., 77, 873-882.
  • Shen H., Ong C., 2000. Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility. Free. Radic. Biol. Med., 15, 529-536.
  • Sonmez M., Turk G., Yuce A., 2005. The effect of ascorbic acid supplementation on sperm quality, lipid per- oxidation and testosterone levels of male Wistar rats. Theriogenology, 63, 2063-2072.
  • Sykes PJ., McCallum BD., Bangay MJ., Hooker AM., Morley AA., 2001. Effect of exposure to 900 MHz radiofre- quency radiation on intrachromosomal recombina- tion in pKZ1 mice. Radiat. Res., 156, 495-502.
  • Thonneau P., Bujan L., Multigner L., Mieusset R., 1998. Occupational heat exposure and male fertility: a review. Human. Reprod., 13, 2122-2125.
  • Tice RR., Hook GG., Donner M., McRee DI., Guy AW., 2002. Genotoxicity of radiofrequency signals. I. In- vestigation of DNA damage and micronuclei induc- tion in cultured human blood cells. Bioelectromag- netics, 23, 113-126.
  • Yan JG., Agresti M., Bruce T., Yan YH., Granlund A., Matloub HS., 2007. Effects of cellular phone emis- sions on sperm motility in rats. Fertil. Steril., 88, 957-964.
  • Yokoi K., Uthus EO., Nielsen FH., 2003. Nickel deficiency diminishes sperm quantity and movement in rats. Biol. Trace. Elem. Res., 93, 141-153.
Toplam 36 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makaleleri
Yazarlar

Barış Uslu

Dide Kılıçalp Kılıç Bu kişi benim

Fetih Gülyüz Bu kişi benim

Yeter Değer

Ömer Uçar Bu kişi benim

Yayımlanma Tarihi 1 Ekim 2012
Yayımlandığı Sayı Yıl 2012 Cilt: 7 Sayı: 2

Kaynak Göster

APA Uslu, B., Kılıçalp Kılıç, D., Gülyüz, F., Değer, Y., vd. (2012). Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 7(2), 77-84.
AMA Uslu B, Kılıçalp Kılıç D, Gülyüz F, Değer Y, Uçar Ö. Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. Ekim 2012;7(2):77-84.
Chicago Uslu, Barış, Dide Kılıçalp Kılıç, Fetih Gülyüz, Yeter Değer, ve Ömer Uçar. “Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 7, sy. 2 (Ekim 2012): 77-84.
EndNote Uslu B, Kılıçalp Kılıç D, Gülyüz F, Değer Y, Uçar Ö (01 Ekim 2012) Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 7 2 77–84.
IEEE B. Uslu, D. Kılıçalp Kılıç, F. Gülyüz, Y. Değer, ve Ö. Uçar, “Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi”, Atatürk Üniversitesi Veteriner Bilimleri Dergisi, c. 7, sy. 2, ss. 77–84, 2012.
ISNAD Uslu, Barış vd. “Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi 7/2 (Ekim 2012), 77-84.
JAMA Uslu B, Kılıçalp Kılıç D, Gülyüz F, Değer Y, Uçar Ö. Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2012;7:77–84.
MLA Uslu, Barış vd. “Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi”. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, c. 7, sy. 2, 2012, ss. 77-84.
Vancouver Uslu B, Kılıçalp Kılıç D, Gülyüz F, Değer Y, Uçar Ö. Cep Telefonundan Yayılan Elektromanyetik Dalganın Erişkin Erkek Kobaylarda Bazı Üreme Parametreleri Üzerine Etkisi. Atatürk Üniversitesi Veteriner Bilimleri Dergisi. 2012;7(2):77-84.
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