Kök Hücre

Yıl 2019, Cilt: 14 Sayı: 2, 221 - 228, 25.10.2019

Ece Çerci , Hatice Erdost

Öz

Doku ve organlarda bulunan, kendini yenileyebilen ve canlının ihtiyacına göre farklılaşarak diğer doku hücrelerine

dönüşebilen ve çoğalabilen hücreler ‘‘Kök Hücre’’ olarak tanımlanır. Kök hücreler; embriyonik kök hücrelerden ve embriyonik

olmayan kök hücrelerden elde edilebilir. Embriyonik olmayan kök hücreler fötal kök hücrelerden, kadavradan, göbek

kordonundan, plasentadan, kemik iliğinden, yağ dokudan, pekçok organda bulunan kök hücrelerden (somatik kök hücreler)

veya son yıllarda farklılaştırma ile herhangi bir hücrenin kök hücre haline dönüştürülmesiyle oluşan hücrelerden elde

edilebilmektedir. Totipotent, pluripotent ve yetişkin mezenkimal kök hücreler rejeneratif tıp, doku mühendisliği, veteriner

hekimliği ile biyomühendislik alanları tarafından büyük ilgi görmektedir. Mezenkimal kök hücrelerin sağlıklı, ekonomik olarak

çoğaltılabilmesi, ihtiyaç duyulan hücre tiplerine dönüştürülebilmesi, kök hücrelerin insan ve hayvanlarda tedavi amaçlı

kullanımını mümkün kılacaktır. Bu derlemede; kök hücre, kök hücrelerin potansiyel kullanım alanları ve özellikle veteriner

hekimlikteki uygulamaları yer almaktadır.

Anahtar Kelimeler

Erişkin Hücre, Pluripotent, Totipotent, Veteriner

Stem Cell

Öz

'' Stem Cell'' is defined as the cell which are found in a tissue or organ which can renew and replicate themselves according to the needs of the body and differentiate into other tissue cells. Stem cells can be obtained from embryonic stem cells and non‐embryonic stem cells. Non‐embryonic stem cells can be obtained from fetal stem cells, cadavers, umbilical cord, placenta, bone marrow, adipose tissue and in many organs (somatic stem cells) or in recent years, differentiation can be obtained from cells formed by transdifferentiating any cell into stem cells. Totipotent, pluripotent and adult mesenchymal stem cells are of great interest by regenerative medicine, tissue engineering, veterinary and bioengineering fields. The ability to reproduce mesenchymal stem cells in healthy, economically, and differentiate them into needed cell types will enable the use of stem cells in order to support the regeneration in humans and animals. This review covers the informations about stem cell, potential use of stem cells and their applications especially in veterinary medicine.

Anahtar Kelimeler

Adult Cell, Pluripotent, Totipotent, Veterinary

Kaynakça

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