Veteriner Hekimlikte Papillomaviruslar ve Önemi

Yıl 2020, Cilt: 15 Sayı: 1, 91 - 99, 30.04.2020

Selvi Deniz Dörttaş Seval Bilge Dağalp

https://doi.org/10.17094/ataunivbd.651002

Cited By: 2

Öz

Papillomaviridae, insanlar dahil tüm omurgalıları enfekte edebilen, enfeksiyöz ajanlara bağlı olan kanser vakalarının % 27-30'undan sorumlu olduğu bilinen en geniş virus ailesidir. Son yıllarda, evcil ve vahşi hayvanlarda çok çeşitli lezyonlara neden olan papillomaviruslar, günümüzde giderek artan sayılarda tespit edilmektedir. Köpeklerde, kedilerde ve sığırlarda oluşan papillomlar veterinerlik alanında önemli bir problemi temsil etmektedir. Papillomaviruslar son yıllarda, büyük çoğunluğu insanlarda ve özellikle sığır, kedi, köpek ve at gibi diğer memeli hayvanlar olmak üzere kuşlar, kaplumbağalar, balıklar gibi memeli olmayan hayvanlarda ve vahşi hayvanlarda artan sayılarda tespit edilmektedir. Özellikle sığır, köpek, at, kemirgen ve insan papillomavirusları hastalıkların tanı, tedavi ve aşı değerlendirmesi için moleküler biyoloji ve hücre biyolojisi üzerine bir model olarak kullanılmakta ve araştırılmaktadır. Yapılan bu araştırmalarla papillomavirus evrimini, biyolojisini, türler arası etkileşimlerini anlama bakımından önemli gelişmeler kaydedilmiştir. Ayrıca çok çeşitli lezyonlara neden olan papillomaviruslar hayvan sağlığı üzerinde büyük etkiler yapabilmekte ve özellikle çiftlik hayvanlarında görülen papillomavirus kaynaklı hastalıklar önemli ölçüde ekonomik kayıplara neden olmaktadır. Bu derlemede, hayvan papillomavirusları hakkındaki son gelişmeleri genel kapsamlarıyla bir araya getirmek ve hızla gelişen bu alanla ilgili bir güncelleme yapmak hedeflenmiştir.

Anahtar Kelimeler

papillomaviruslar, at, sığır, kedi, köpek

Papillomaviruses and Their Importance in Veterinary Medicine

Öz

Papillomaviridae is the largest family of viruses known to be responsible for 27-30% of cancer cases due to infectious agents that can infect all vertebrates, including humans. In recent years, papillomaviruses, which cause a wide variety of lesions in domestic and wild animals, are now increasingly identified and papillomas in dogs, cats and cattle represent an important problem in veterinary medicine. In recent years, papillomaviruses have been detected in increasing numbers in humans and in non-mammals such as birds, turtles, fish, and other wild animals, particularly other mammals such as cattle, cats, dogs and horses. In particular, cattle, dogs, horses, rodents and human papillomaviruses are used as a model on molecular biology and cell biology for the diagnosis, treatment and vaccine evaluation of diseases. With these studies, important developments have been made in terms of understanding the evolution, biology and inter-species interactions of papillomavirus. In addition, papillomaviruses, which cause a wide variety of lesions, can have great effects on animal health, and especially papillomavirus-related diseases in farm animals cause significant economic losses. This study aims to bring together the latest developments in animal papillomaviruses with their general scope and make an update on this rapidly developing field.

Anahtar Kelimeler

Bovine, Cat, Dog, Horse, Papillomaviruses

Kaynakça

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