Peptit terapötikleri ile kanser tedavisi

Öz

Özet Peptit terapötikleri, geleneksel küçük moleküllü ilaçlara göre pek çok avantajı bulunmasından dolayı sağlık alanında giderek artan bir ilgi görmektedir. Peptitler, vücutta doğal olarak bulunmaları, geleneksel ilaçların ulaşamayacağı bir düzeyde özgüllükleri, vücuttaki yarı ömürlerinin arttırılabilmesi gibi avantajlara sahiptir. Bu avantajlar, peptit terapötiklerini yeni tedaviler geliştirmek için umut verici bir araştırma alanı haline getirmektedir. Küresel Peptit Terapötikleri pazarına ilişkin bir rapora göre, %6,6’lık büyüme oranıyla sektörün 2030 yılına kadar 69,3 milyar dolara ulaşması bekleniyor [1] . Bu alandaki araştırmalar ilerlemeye devam ettikçe, peptit terapötikleri sağlık hizmetlerinde ve hasta sonuçlarında büyük iyileştirme potansiyeline sahip olacaktır. Terapötik peptitlerin çok yönlülüğü, kanser tedavisinde birden fazla yaklaşıma olanak tanır ve araştırmalar, yenilikçi peptit bazlı tedavilerin geliştirilmesine odaklanmaktadır. Bu derlemede, peptit terapötiklerinin kanserde uygulamaları tartışılmaktadır. İnceleme ayrıca bu alanda kullanılan peptitleri, tasarımı ve geliştirilmesinde ortaya çıkan yeni fırsatları ve kanserde peptit terapötiklerinin geleceğini ortaya koyuyor.

Anahtar Kelimeler

• pepetit terapötikleri
• kanser
• muc 4

Cancer treatment with peptide therapeutics

Öz

Peptide therapeutics are gaining increasing attention in healthcare because of their many advantages over traditional small-molecule drugs. Peptides have advantages such as being naturally present in the body, being specific at a level that traditional drugs cannot reach, and increasing their half-life in the body. These advantages make peptide therapeutics a promising area of research for developing new treatments. According to a report on the global Peptide Therapeutics market, with a growth rate of 6.6%, the industry is expected to reach $69.3 billion by 2030 [1] . As research in this area continues to advance, peptide therapeutics will have the potential to greatly improve healthcare and patient outcomes. The versatility of therapeutic peptides enables multiple approaches to cancer treatment, and research is focused on the development of innovative peptide-based therapies. In this review, the applications of peptide therapeutics in cancer are discussed. The review also highlights the peptides used in this field, emerging opportunities in their design and development, and the future of peptide therapeutics in cancer.

Anahtar Kelimeler

• peptide therapeutics
• cancer
• Muc 4

Kaynakça

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