Cancer treatment with peptide therapeutics

Yıl 2023, Cilt: 6 Sayı: 3, 193 - 203, 28.11.2023

Emel Savul , Berrin Erdağ

Öz

Peptide therapeutics are gaining increasing attention in healthcare because of their many
advantages over traditional small-molecule drugs. Peptides have advantages such as being
naturally present in the body, being specific at a level that traditional drugs cannot reach, and
increasing their half-life in the body. These advantages make peptide therapeutics a promising
area of research for developing new treatments. According to a report on the global Peptide
Therapeutics market, with a growth rate of 6.6%, the industry is expected to reach $69.3
billion by 2030 [1] . As research in this area continues to advance, peptide therapeutics will
have the potential to greatly improve healthcare and patient outcomes. The versatility of
therapeutic peptides enables multiple approaches to cancer treatment, and research is focused
on the development of innovative peptide-based therapies. In this review, the applications of
peptide therapeutics in cancer are discussed. The review also highlights the peptides used in
this field, emerging opportunities in their design and development, and the future of peptide
therapeutics in cancer.

Anahtar Kelimeler

peptide therapeutics, cancer, Muc 4

Peptit terapötikleri ile kanser tedavisi

Öz

Özet
Peptit terapötikleri, geleneksel küçük moleküllü ilaçlara göre pek çok avantajı bulunmasından
dolayı sağlık alanında giderek artan bir ilgi görmektedir. Peptitler, vücutta doğal olarak
bulunmaları, geleneksel ilaçların ulaşamayacağı bir düzeyde özgüllükleri, vücuttaki yarı
ömürlerinin arttırılabilmesi gibi avantajlara sahiptir. Bu avantajlar, peptit terapötiklerini yeni
tedaviler geliştirmek için umut verici bir araştırma alanı haline getirmektedir. Küresel Peptit
Terapötikleri pazarına ilişkin bir rapora göre, %6,6’lık büyüme oranıyla sektörün 2030 yılına
kadar 69,3 milyar dolara ulaşması bekleniyor [1] . Bu alandaki araştırmalar ilerlemeye devam
ettikçe, peptit terapötikleri sağlık hizmetlerinde ve hasta sonuçlarında büyük iyileştirme
potansiyeline sahip olacaktır. Terapötik peptitlerin çok yönlülüğü, kanser tedavisinde birden
fazla yaklaşıma olanak tanır ve araştırmalar, yenilikçi peptit bazlı tedavilerin geliştirilmesine
odaklanmaktadır. Bu derlemede, peptit terapötiklerinin kanserde uygulamaları
tartışılmaktadır. İnceleme ayrıca bu alanda kullanılan peptitleri, tasarımı ve geliştirilmesinde
ortaya çıkan yeni fırsatları ve kanserde peptit terapötiklerinin geleceğini ortaya koyuyor.

Anahtar Kelimeler

pepetit terapötikleri, kanser, muc 4

Kaynakça

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