Curcuma longa Ticari Ekstresinin In-Vitro Antibakteriyel Aktivitesinin Araştırılması

Yıl 2018, Cilt: 1 Sayı: 1, 1 - 6, 29.06.2018

Şinasi Aşkar Şeyma Nur Deveboynu

Öz

New plant-derived antibacterial agent researches have
increased in recent years, because of increased resistance to antimicrobial
agents that used against to pathogen microorganisms, and unwanted side effects
of food additives.

The aim of this research was to investigate the,
in-vitro antibacterial activities and minimal inhibitory concentration of Curcuma longa which obtained from India,
commercial plant extracts against some nosocomial pathogens (Extended Spectrum
Beta Lactamase Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, Methicillin
Resistant Staphylococcus aureus), by
disk diffusion and broth microdilution methods.

The diameter of the inhibition zone in the
disc-diffusion method shows that Curcuma
longa extract (6.12 mg/disc) has antibacterial activity only on MRSA
(Inhibition zone diameter 8 mm). However, with broth micro dilution method, Curcuma longa extract had minimal
inhibitor concentration (4.87-78 mg/ml) on all bacteria in different levels. Curcuma longa extract showed the minimum
MIC value on S.aureus, maximum MIC
value on E.coli, K.pneumoniae and E. faecalis. The results were consistent
in both methods at equal concentrations applied from the Curcuma longa extract.

In conclusion, particularly Curcuma longa leaf extract is thought to be effective against to MRSA,
E. coli, K. pneumoniae, P. aeruginosa,
E. faecalis in many areas like medical and food industries. However,
there are need new in vivo studies in
future.

Anahtar Kelimeler

Broth microdilution, Disk diffusion, Inhibition, Nosocomial

Investigation of In-Vitro Antibacterial Activity of Curcuma longa Commercial Extract

Öz

Kaynakça

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