MANTAR BİLEŞENLERİNİN TERÖPATİK ETKİLERİ

Yıl 2009, Cilt: 38 Sayı: 1, 19 - 24, 01.03.2009

Aysun Öztürk Ö. Utku Çopur

Öz

Mantarlar, yüzyıllar boyunca yiyecek olarak tüketildiği gibi birçok hastalığın
tedavisi amacıyla ilaç olarak da kullanılmıştır. Son yıllardaki bilimsel çalışmalar
mantarlar tarafından üretilen bileşenlerin teröpatik (tedavi edici) özelliklere sahip
olduğunu göstermiştir. Bu makalede; insan sağlığı üzerindeki olumlu etkilerinden
dolayı tıbbi mantar olarak nitelendirilen mantar türleri ve bileşenleri ele alınarak,
bilimsel araştırmaların ışığında incelenmiştir.

Anahtar Kelimeler

Tıbbi Mantarlar, Maitake, Reishi, Shitake, Teröpatik Etki

Kaynakça

• 1. Anonymous, 2006. The Use of Mushroom Preparations in Malignancies. Thomas Jefferson University Hospital , July 2006.
• 2. Anonymous, 2009. Food and Agriculture Organization of the United Nations (FAO), (http://faostat.fao.org).
• 3. Benedict, R.G. and L.R. Brady, 1972. Antimicrobial Activity of Mushroom Metabolites. Jour. of Pharmaceutical Sciences 61 (11), 1820- 182.
• 4. Carlile, M.J. and S. C. Watkinson, 1994. The Fungi. Academic Press London, pp.373-409.
• 5. Chang, S. T. and J. A. Buswell, 1996. Mushroom Nutriceuticals. World J. Microbiol Biotechnol 12, 473-476.
• 6. Chang, S. T., 1999. World Production of Cultivated Edible and Medicinal Mushrooms in 1997 With Emphasis on Lentinus edodes (Berk.) Sing. in China. International J. Med. Mush. 1: 291–300.
• 7. Conchran, K.W., 1978. Medicinal Effects, in: The Biology and Cultivition of Edible Musrooms (Ed. Chung, S.T. and Hayes, W.A.), Academic Press, New York.
• 8. Denis, R. B., 1995. Mushrooms : Poisons and Panaceas, W.H. Freeman and Co, New York.
• 9. Fujimiya, Y., Y. Suzuki, K. Oshiman, H. Kobori, K. Moriguchi, H. Nakashima, Y. Matumoto, S. Takahara, T. Ebina and R. Katakura, 1998. Selective Tumoricidal Effect of Soluble Proteoglucan Extracted From the Basidiomycete, Agaricus blazei Murill, Mediated Via Natural Killer Cell Activation and Apoptosis. Cancer Immunol Immunother, 46:147-159.
• 10. Hajjaj, H., C. Macé, M. Roberts, P. Niederberger and LB. Fay, 2005. Effect of 26-Oxygenosterols from Ganoderma lucidum and Their Activity as Cholesterol Synthesis Inhibitors. Appl. Environ. Microbiol.;71(7):3653-8.
• 11. Karmali, A., 2008. SOD Activity, Cytochrome P-450, Cytochrome P-450 Reductase and Secondary Metabolites - Chemical and Biological Properties in Mushroom Nutrition. International Mycotherapy Institute. Page 9-11
• 12. Lakhanbal, T.N. and M. Rana 2005. Medicinal and Nutraceutical Genetic Resources of Mushrooms. Cambridge University Pres, Plant Genetic Resources, 3, pp 288-303.
• 13. Liu, Y. K. and W. Shen, 2003. Inhibitive Effect of Cordyceps sinensis on Experimental Hepatic Fibrosis and its Possible Mechanism. World J. Gastroenterol 9 (3):529-533.
• 14. Mayell, M., 2001. Maitake Extracts and Their Therapeutic Potential – A Review. Alternative Medicine Review - Volume 6, Number 1:48-60.
• 15. Mizuno, T., 1999. The Extraction and Development of Antitumor – Active Polysaccharides from Medical Mushrooms in Japan (Review). International Journal of Medical Mushrooms, (1) 1: 9-29.
• 16. Nanba, H. and K. Kubo, 1997. Effect of Maitake D-Fraction on Cancer Prevention. Ann N Y Acad Sci., 1997; 833: 204- 207.
• 17. Okuda, K. L., 2007. Nature’s Powerful Immune Support from the Brazilian Rainforests. Nutrition Professional’s Journal Volume 7:14-17.
• 18. Sarıkürkçü, C., S.D Karslı, M.H. Solak ve M. Harmandar, 2004. MuğlaYöresi Yenilebilir Mantar Ekstraktlarının Antioksidant Aktivitelerinin Belirlenmesi. Türkiye 8. Gıda Kongresi. 26- 28 Mayıs 2004. Bursa. s. 57.
• 19. Wasser, S.P. and A.L. Weis, 1999. Medical Properties of Substances Occurring in Higher Basidiomycetes Mushrooms: Current Perspectives (Review). International Journal of Medical Mushrooms, (1)1: 31- 62.
• 20. Yamaguchi, Y., S. Kagota, K. Nakamura, K. Shinozuka and M. Kunitomo, 2000. Antioxidant Activity of the Extracts from Fruiting Bodies of Cultured Cordyceps sinensis. Phytotherapy Research. Volume: 14;8: 647-649.
• 21. Yamamura, Y. and K.W., Cochran, 1974a. Chronic hypocholesterolemic Effect of Lentinus edodes in Mice and Absence of Effect on Scrapie. Mushroom Sci., 9: 489- 493.
• 22. Yamamura, Y., Cochran, K.W., 1974b. A selective inhibitor of myxoviruses from shiitake (L. edodes). Mushroom Sci., 9: 495- 507.
• 23. Zhang, H., F. Gong, Y. Feng and C. Zhang, 1999. Flammulin Purified from the Fruit Bodies of Flammulina velutipes (Curt .:Fr.) P. Karst. International Journal of Medical Mushrooms, (1)1: 89- 92. .