Diabetic wound healing with medicinal plants: Past and present approaches

Yıl 2025, Cilt: 6 Sayı: 3, 209 - 222, 30.12.2025

Pranjal Sachan , Anjali Pandey

https://doi.org/10.53445/batd.1701433

Öz

Diabetic wounds are characterized by their tendency to heal slowly, exhibit persistent inflammation, and become readily infected, which significantly complicates the overall wound-healing process. While conventional treatments often fall short in delivering lasting solutions, medicinal plants have emerged as a promising alternative for wound care. Rooted in ancient healing traditions, these herbal remedies are now gaining scientific recognition for their effectiveness in managing diabetic wounds. Compounds such as flavonoids, alkaloids, tannins, and terpenoids contribute to wound healing by exhibiting antimicrobial, anti-inflammatory, antioxidant, and angiogenic properties. These bioactive constituents accelerate tissue regeneration while minimizing complications, making them valuable in diabetic wound management. This review aims to connect traditional herbal wisdom with modern scientific insights by exploring key medicinal plants, their phytochemical mechanisms, and their therapeutic benefits in wound healing. With further clinical research and advancements in biotechnology, these natural remedies could become integral to mainstream diabetic wound care, providing safer, more affordable, and sustainable treatment options.

Anahtar Kelimeler

Diabetic wounds , herbal medicine , phytotherapy , tissue regeneration , angiogenesis , inflammation

Diyabetik yaraların bitkisel tedavisi: Geçmişten günümüze yaklaşımlar

Öz

Diyabetik yaralar, yavaş iyileşme, sürekli iltihaplanma ve kolayca enfekte olmaları ile karakterizedir; bu durum, yara iyileşme sürecini önemli ölçüde zorlaştırır. Konvansiyonel tedaviler çoğu zaman kalıcı çözümler sunmakta yetersiz kalırken, tıbbi bitkiler yara bakımında umut verici bir alternatif olarak öne çıkmaktadır. Kadim şifa geleneklerine dayanan bu bitkisel çözümler, günümüzde diyabetik yaraların yönetiminde etkinlikleri açısından bilimsel olarak da tanınmaktadır. Flavonoidler, alkaloidler, tanenler ve terpenoidler gibi bileşikler; antimikrobiyal, anti-inflamatuar, antioksidan ve anjiyojenik özellikleri sayesinde yara iyileşmesini desteklemektedir. Bu biyoaktif bileşenler, komplikasyonları minimize ederken doku rejenerasyonunu hızlandırmakta ve diyabetik yara yönetiminde değerli bir rol oynamaktadır. Bu derleme, geleneksel bitki bilgeliğini modern bilimsel bulgularla birleştirmeyi amaçlayarak, başlıca tıbbi bitkileri, fitokimyasal mekanizmalarını ve yara iyileşmesindeki terapötik faydalarını incelemektedir. Daha fazla klinik araştırma ve biyoteknolojik gelişmeler ile bu doğal çözümler, diyabetik yara bakımında daha güvenli, uygun maliyetli ve sürdürülebilir tedavi seçenekleri sunarak ana akım tedavinin ayrılmaz bir parçası hâline gelebilir.

Anahtar Kelimeler

Diyabetik yaralar , bitkisel ilaç , fitoterapi , doku rejenerasyonu , anjiyogenez , inflamasyon

Kaynakça

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