Recent Developments in Natural Compounds Obtained from Marine Molluscs

Yıl 2019, Cilt: 1 Sayı: 1, 42 - 54, 31.12.2019

Tuğba Buse Avcı , Zafer Ömer Özdemir

Öz

Mollusca is the
philum which has the richest number of species after Arthrpoda. Diversity in
species number, diverse morphology and ecological niches, lack of acquired immunological
memories and the development of various defense mechanisms and a large number
of unexplored active compounds make this group a good candidate for natural
product chemistry research and new drug discovery. Marine organisms, especially mollusca, have great
potential as they contain many secondary metabolites that have not yet been
discovered.

The aim of this study is
to examine the current literature on mollusca secondary metabolites to
complement the main gaps in our knowledge of mollusca chemistry. In this way,
by contributing to future research in the field of natural product chemistry,
it will be possible to help improve the targets.

Anahtar Kelimeler

Mollusca, Secondary metabolites, Antimicrobial peptides, Natural product chemistry

Deniz Yumuşakçalarından Elde Edilen Doğal Bileşiklere Dair Güncel Gelişmeler

Öz

Mollusca
(Yumuşakça) Arthrpoda’dan sonra en zengin tür sayısına sahip filumdur. Tür
sayısındaki çeşitlilik, çok çeşitli morfolojileri ve ekolojik nişleri,
kazanılmış immünolojik hafızaları bulunmadığı için çeşitli savunma
mekanizmaları geliştirmeleri ve aydınlatılmamış çok sayıda aktif bileşiği bu
grubu doğal ürün kimyası araştırmaları ve yeni ilaç keşfi için iyi bir aday
haline getirmektedir. Deniz canlıları, özellikle yumuşakçalar, henüz
keşfedilmemiş pek çok sekonder metabolit barındırdıkları için, büyük bir
potansiyel barındırmaktadır.

Bu çalışmanın amacı,
yumuşakça kimyası bilgimizdeki ana boşlukları tamamlamak için yumuşakça sekonder
metabolitleri hakkındaki güncel literatürü incelemektir. Bu sayede, doğal ürün
kimyası alanında gelecekte yapılacak araştırmalara katkı sağlanarak, hedeflerin
iyileştirilmesine yardımcı olma imkânı doğacaktır.

Anahtar Kelimeler

Mollusca, Antimikrobiyal peptitler, Doğal Ürün Kimyası, Sekonder metabolit

Kaynakça

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