Neonatal Dönem Buzağı İshallerinde Clostridium difficile

Yıl 2018, Cilt: 7 Sayı: 1, 33 - 41, 20.07.2018

Ediz Kağan Özgen Murat Yıldırım

Öz

Clostridium difficile, insanlarda antibiyotik
ilişkili diyare vakalarının etiyolojik ajanı olmasının yanında çiftlik
hayvanlarında özellikle neonatal dönemde ishallere sebep olmaktadır. Bakterinin
birçok antimikrobiyal etken maddesine dirençli olması sebebiyle hastalık
vakalarının tedavisi sınırlı kalabilmektedir. Etken toksin A, toksin B ve
binary toksin olmak üzere üç toksin üretebilmekte ve klinik semptomlar bu
toksinlerin bağırsaklarda meydana getirdiği hasar sonucunda ortaya çıkmaktadır.
Bu derleme ile C. difficile’nin
epidemiyolojisi, patogenezi, teşhisi, tedavisi ve buzağı ishallerinde rolü
hakkında bilgi verilmektedir.

Anahtar Kelimeler

Clostridium difficile, neonatal buzağı, ishal

Clostridium difficile in Neonatal Calf Diarrhea

Öz

Clostridium difficile is an etiological agent of
antibiotic-associated diarrhea in humans, as well as diarrhea in farm animals,
especially in the neonatal period. Because bacteria is resistant to many antimicrobial
agents, the treatment of disease cases can be limited. The active toxin can
produce three toxins, toxin A, toxin B and binary toxin, and clinical symptoms
arise as a result of damage caused by these toxins in the intestines. This
review provides information on the role of C.
difficile in epidemiology, pathogenesis, diagnosis, treatment and calf
diarrhea.

Anahtar Kelimeler

Clostridium difficile, neonatal calf, diarrhea

Kaynakça

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