Kronik Hepatit B Enfeksiyonu, Siroz ve Antiviral Tedavi İlişkili Sarı Ürtiker Olgusu

Öz

Ürtiker; mast hücre degranülasyonuna bağlı olarak kaşıntılı eritemli plaklar ile seyreden yaygın görülen inflamatuar deri hastalığıdır. Klinikte eritemli ve ödemli papül ve plaklar ile seyreder. Serumda hiperbilirubinemi tespit edilen ürtikerli hastalarda ise deride sarımsı plaklar görülebilir. Literatürde kronik karaciğer hastalığı, akut karaciğer yetmezliği, biliyer hastalıklar, transfüzyon ve antiviral tedaviler ile ilişkili sarı ürtiker vakalarının ortaya çıktığı bildirilmiştir. Biz de bu olguda hepatit B enfeksiyonuna bağlı karaciğer sirozu tanısıyla takipli ve antiviral tedavi alan, sarı ürtikeryal plak ve papülleri ortaya çıkan bir hasta sunmayı ve ürtikerli hastalarda hiperbilirubinemiye bağlı olarak sarı ürtikeryal makül, papül ve plakların görülebileceğinin farkındalığını oluşturmayı amaçladık.

Anahtar Kelimeler

• Ürtiker
• sarı ürtiker
• hiperbilirubinemi
• hepatit B enfeksiyonu

A Case of Yellow Urticaria Associated with Chronic Hepatitis B Infection, Cirrhosis, and Antiviral Treatment

Öz

Urticaria is a common inflammatory skin disease characterized with itchy erythematous plaques due to mast cell degranulation. Clinically, it is characterized by erythematous and edematous papules and plaques. In patients with urticaria, in whom hyperbilirubinemia is detected in the serum, yellowish plaques can be seen on the skin. In the literature, cases of yellow urticaria associated with chronic liver disease, acute liver failure, biliary diseases, transfusion and antiviral treatments have been reported. In this case, we aimed to present a patient with hepatic cirrhosis due to hepatitis B infection, who was followed up and received antiviral therapy, who developed yellow urticarial papules, and plaque, and to raise awareness that yellow urticarial macules, papules and plaques can be seen due to hyperbilirubinemia in patients with urticaria.

Anahtar Kelimeler

• Hepatitis B
• urticaria
• Hyperbilirubinemia

Kaynakça

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