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Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children

Cilt: 9 Sayı: 2 30 Ağustos 2025
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Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children

Öz

Serum alkaline phosphatase concentration rises in some disease states. On the other hand, benign transient hyperphosphatasemia is most commonly recognized in infants and children younger than 2 years of age. It has also been described in adults. Benign transient hyperphosphatasemia is a self-limiting condition that is usually accompanied by some infectious and allergic disorders. Therefore it is important to keep this entity in mind to avoid unnecessary investigations. Here, we report two children who were diagnosed with benign transient hyperphosphatasemia following gastroenteritis.

Anahtar Kelimeler

Kaynakça

  1. Corathers S.D. (2006) The alkaline phosphatase level: nuances of a familiar test. Pediatr Rev., 27:382–384.
  2. Crofton P.M. (1988) What is the cause of benign transient hyperphosphatasemia? A study of 35 cases. Clin Chem., 34:335-340.
  3. Gualco G., Lava S.A., Garzoni L, et al. (2013) Transient benign hyperphophatasemia. J Pediatr Gastroenterol Nutr., 57:167-171.
  4. Huh S.Y., Feldman H.A., Cox JE, Gordon CM. (2009) Prevalence of transient hyperphosphatasemia among healthy infants and toddlers. Pediatrics. 124:703–709.
  5. Kraut JR, Metrick M., Maxwell NR, Kaplan MM., (1985) Isoenzyme studies in transient hyperphosphatasemia of infancy. Ten new cases and a review of the literature. Am J Dis Child., 139:736–740.
  6. Otero JL, González-Peralta RP, Andres JM, Jolley CD, Novak DA, Haafiz A. (2011) Elevated Alkaline Phosphatase in Children: An Algorithm to Determine When a "Wait and See" Approach is Optimal. Clin Med Insights Pediatr., 5:15-18.
  7. Schonhaut B L, Rocha R A. (2017) Hiperfosfatasemia transitoria benigna de la infancia: Serie clínica [Benign transient hyperphosphatasaemia in infants: Clinical series]. Rev Chil Pediatr., 88:169-175. Spanish. Shkalim Zemer V, Hoshen M, Levinsky Y, et al. (2023) Benign transient hyperphosphatasemia in infants and children: a retrospective database study. Eur J Pediatr. 2:1–6.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri (Diğer)

Bölüm

Olgu Sunumu

Erken Görünüm Tarihi

28 Ağustos 2025

Yayımlanma Tarihi

30 Ağustos 2025

Gönderilme Tarihi

11 Ocak 2025

Kabul Tarihi

20 Ağustos 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 9 Sayı: 2

Kaynak Göster

APA
Yıldız, G., Yıldırım, E., Torun Bayram, M., Kavukçu, S., & Soylu, A. (2025). Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children. Balıkesir Medical Journal, 9(2), 109-113. https://doi.org/10.33716/bmedj.1617632
AMA
1.Yıldız G, Yıldırım E, Torun Bayram M, Kavukçu S, Soylu A. Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children. BMedJ. 2025;9(2):109-113. doi:10.33716/bmedj.1617632
Chicago
Yıldız, Gizem, Erkam Yıldırım, Meral Torun Bayram, Salih Kavukçu, ve Alper Soylu. 2025. “Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children”. Balıkesir Medical Journal 9 (2): 109-13. https://doi.org/10.33716/bmedj.1617632.
EndNote
Yıldız G, Yıldırım E, Torun Bayram M, Kavukçu S, Soylu A (01 Ağustos 2025) Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children. Balıkesir Medical Journal 9 2 109–113.
IEEE
[1]G. Yıldız, E. Yıldırım, M. Torun Bayram, S. Kavukçu, ve A. Soylu, “Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children”, BMedJ, c. 9, sy 2, ss. 109–113, Ağu. 2025, doi: 10.33716/bmedj.1617632.
ISNAD
Yıldız, Gizem - Yıldırım, Erkam - Torun Bayram, Meral - Kavukçu, Salih - Soylu, Alper. “Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children”. Balıkesir Medical Journal 9/2 (01 Ağustos 2025): 109-113. https://doi.org/10.33716/bmedj.1617632.
JAMA
1.Yıldız G, Yıldırım E, Torun Bayram M, Kavukçu S, Soylu A. Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children. BMedJ. 2025;9:109–113.
MLA
Yıldız, Gizem, vd. “Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children”. Balıkesir Medical Journal, c. 9, sy 2, Ağustos 2025, ss. 109-13, doi:10.33716/bmedj.1617632.
Vancouver
1.Gizem Yıldız, Erkam Yıldırım, Meral Torun Bayram, Salih Kavukçu, Alper Soylu. Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children. BMedJ. 01 Ağustos 2025;9(2):109-13. doi:10.33716/bmedj.1617632