The effects of copper- and levonorgestrel-intrauterine devices on cervical cytology

Öz

Objective: To investigate whether there is any change in cervical cytology before and after Copper- and Levonorgestrel-Intrauterine device (IUD) insertion.

Material and Methods: Pap smear results before and after Copper- and Levonorgestrel-IUD were evaluated retrospectively. All of the study specimens consisted of conventional Pap smear samples.

Results: Among the women included in the study, 52 of them were inserted copper- and 24  levonorgestrel-IUD. All women had normal cytological examination results prior to IUD. There were no cases of atypia or cancer in the two groups after IUD. Non-specific inflammatory changes in 20 women (38.5%) and ASC-US in 6 women (11.5%) were found in the copper-IUD group, whereas 10 (41.7%) and 3 (12.5%) women were present in the levonorgestrel -UD group, respectively. There was no statistically significant difference between the two groups in terms of Pap smear results after IUD insertion.

Conclusion: Copper- and levonorgestrel-IUD do not cause neoplasia. But they may lead to similar inflammatory changes on endometrial and cervical cells.

Anahtar Kelimeler

• copper,levonorgestrel,intrauterine device,smear

Bakırlı ve levonorgestrelli rahim içi araçların servikal sitolojiye etkileri

Öz

Amaç: Bakırlı ve levonorgestrelli Rahim içi araç (RİA) uygulanan kadınlarda, RİA uygulaması öncesi ve sonrası servikal sitolojide herhangi bir değişiklik olup olmadığını araştırmak

Gereç ve Yöntemler: Bakırlı ve levonorgestrelli RİA uygulanan kadınların, RİA öncesi ve sonrası Pap smear sonuçları retrospektif olarak incelenmiştir. Çalışma preparatlarının tamamı konvansiyonel Pap smear örneklerinden oluşmuştur.

Bulgular: Çalışmaya dahil edilen kadınların 52 tanesine bakırlı, 24 tanesine levonorgestrelli RİA uygulanmıştır. Tüm kadınlar RİA öncesi normal sitolojik inceleme sonucuna sahipti. RİA sonrası örneklerde, İki grupta da atipi ya da kanser olgusuna rastlanmadı. Bakırlı RİA grubunda 20 kadında (38.5%) non-spesifik inflamatuar değişiklik ve 6 kadında (11.5%) ASC-US mevcutken,  levonorgestrelli RİA grubunda bu sayılar sırasıyla 10 (41.7%) ve 3 (12.5%) idi. İki grup arasında RİA uygulaması sonrası Pap smear sonuçları açısından istatistiksel olarak anlamlı bir fark yoktu.

Sonuç: Bakırlı ve levonorgestrelli RİA kullanımı neoplazi gelişimine neden olmaz. Fakat endometrial ve servikal hücreler üzerinde bir takım benzer inflamatuar değişiklikler yapabilirler.

Anahtar Kelimeler

• bakır,levonorgestrel,rahim içi araç,smear

Kaynakça

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