Kronik Migren Hastalarında Lipit Profilleri Arasındaki İlişki

Yıl 2020, , 5 - 12, 09.03.2020

Mehmet Özdin

https://doi.org/10.33716/bmedj.669168

Öz

Amaç: Bu çalışmada amacımız, Sakarya Üniversitesi Eğitim ve Araştırma Hastanesi (SÜEAH) Nöroloji ve Beyin Cerrahisi polikliniğine müracaat eden Migren hastalarında lipit düzeylerini tespit etmek ve Migren ile lipit düzeyleri arasındaki bu ilişkiyi araştırmaktır.
Gereç ve Yöntemler: Çalışmamıza dahil ettiğimiz veriler 01.01.2018-30.09.2019 tarihleri arasındaki müracaat eden ve 20 yaş üzerindeki Migren hastalarından hastane bilgi yönetimi sistemi (HBYS) üzerinden retrospektif olarak elde edildi. Hasta ve kontrol grubu aralarındaki ilişki ve farklar araştırıldı. Hasta ve kontrol grubuna diyabet ve hipertansiyon lipit düzeylerini olumsuz etkileyecek durumlar ile malignite ve kronik nörolojik hastalığı olanlar alınmadı.
Bulgular: Çalışma kriterlerine uyan 48 migren hastasının 36 kadın, 12 erkek olup, yaş ortalaması 42.17±11.24 olarak tespit edildi. Kontrol grubunda 48 olgunun 15’i erkek, 33’ü kadın olmak üzere yaş ortalaması 47.15±17.04 yıl olarak belirlendi. Çalışmada; total kolesterol (TK), trigliserid (TG), düşük dansiteli lipoprotein (LDL) ve yüksek dansiteli lipoprotein (HDL) düzeyleri tespit edildi. Migren hastalarının ortalama lipit değerleri (mg/dl olarak), TK 213.38±38.50, TG 238.31±66.49, LDL 164.38±24.06 düzeyleri yüksek değerlerde iken, HDL 52±9 düzeyleri düşük değerlerde saptandı. Kontrol grubunun ortalama lipit değerleri (mg/dl olarak), TK 169.52±51.55, TG 103.29±38.15, LDL 126.98±35.58 ve HDL 54.52±7.31 olarak saptandı. Migren hastaları ile kontrol grubu istatistiksel olarak TK, TG, LDL ve HDL için karşılaştırıldığında istatistiksel olarak anlamlı (p<0.05) olduğu saptandı.
Sonuç: Migren hastalarında lipit profilleri olumsuz etkilenmektedir. Lipit profillerinin düzeltilmesi ve önleyici tedbirlerin alınması, klinik bulguların daha hafif seyretmesine ve hasta şikâyetlerini en aza inmesine katkı sağlayacaktır.

Anahtar Kelimeler

migren, lipit profiller, hastane bilgi yönetimi sistemi

Destekleyen Kurum

Herhangi bir kurum tarafından desteklenmemiştir

Proje Numarası

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The Relationship Between Migraine and Lipid Profile in Chronic Migraine Patients

Öz

Aim: The aim of this study was to determine the lipid levels of migraine patients who applied to the Neurology and Neurosurgery outpatient clinic of Sakarya University Training and Research Hospital (SÜEAH) and to investigate this relationship between migraine and lipid levels.
Materials and Methods: The data included in our study were obtained retrospectively from the hospital information management system (HIS) of migraine patients over 20 years of age who applied between 01.01.2018-30.09.2019. The relationship and differences between the patient and control groups were investigated. Patients and controls were not included in conditions that would adversely affect the lipid levels of diabetes and hypertension, and those with malignancy and chronic neurological disease.
Results: Of the 48 migraine patients who met the study criteria, 36 were female and 12 were male. The mean age was 42.17±11.24 years. The mean age was 47.15±17.04 years in the control group, of which 15 were male and 33 were female. Study; Total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) levels were determined. The mean lipid values (mg / dl), TC 213.38±38.50, TG 238.31±66.49, LDL 164.38±24.06, and HDL 52 ± 9 levels of migraine patients were found to be low. The mean lipid values (mg / dl) of the control group were TC 169.52±51.55, TG 103.29±38.15, LDL 126.98 ± 35.58 and HDL 54.52±7.31. Migraine patients and control groups were statistically significant (p <0.05) when compared to TC, TG, LDL and HDL.
Conclusion: Lipid profiles are negatively affected in migraine patients. Correcting lipid profiles and taking preventive measures will contribute to the milder clinical findings and to minimize patient complaints.

Anahtar Kelimeler

migraine, lipit profiles, hospital information management system

Proje Numarası

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Kaynakça

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