A New Approach in Differential Diagnosis of Colon Polyps; Stereology

Öz

Aim: The aim of this study is; to investigate the value of the stereology method that can be used in the diagnosis of colon polyps, which may also have neoplastic potential and have diagnostic difficulties based on histopathological classification.
Materials and Methods: In this study, 236 cases of colorectal polyps were included and according to the histomorphological features determined in the World Health Organization classification of 2010. The cases were grouped as hyperplastic polyps, serrated adenomas, tubular adenomas, tübülövillöz adenoma and villous adenoma. They were measured with the stereological methods and the data obtained were compared.
Results: When the cases were evaluated according to their gender, male gender was predominant. When the data obtained as a result of stereological measurements were compared between the groups, there were differences in many parameters.
Conclusion: In addition to histopathological features, stereological studies are also valuable in classifying polyps.

Anahtar Kelimeler

• Stereology
• colon
• polyp
• diagnosis
• clinicopathological features

Kolon Poliplerinin Ayırıcı Tanısında Yeni Bir Yaklaşım; Stereoloji

Öz

Amaç: Bu çalışmanın amacı; neoplastik potansiyeli de olabilen kolon poliplerinin histopatolojik özelliklerine göre sınıflandığında tanı güçlüğü oluşturabilen olgular için tanıda kullanılabilecek stereoloji yönteminin değerini araştırmaktır.
Gereç ve Yöntemler: Bu çalışmaya 236 adet kolorektal polip olgusu dahil edilmiş ve olgular Dünya Sağlık Örgütü’nün 2010 yılı sınıflamasına göre histomorfolojik özellikleri göz önüne alınarak hiperplastik polip, serrated adenom, tübüler adenom, tübülövillöz adenom, villöz adenom şeklinde gruplara ayrılmıştır. Olguların stereolojik yöntemler ile ölçümleri yapılarak elde edilen veriler karşılaştırılmıştır.
Bulgular: Olgular cinsiyetlerine göre değerlendirildiğinde erkek cinsiyet ağırlıktaydı. Stereolojik ölçümler sonucu elde edilen veriler gruplar arasında karşılaştırıldığında birçok parametrede farklılıklar mevcuttu.
Sonuç: Poliplerin sınıflandırılmasında histopatolojik özellikler yanısıra stereolojik çalışmalar da kıymetlidir.

Anahtar Kelimeler

• stereoloji,
• kolon
• polip
• tanı
• klinikopatolojik özellikler

Destekleyen Kurum

Herhangi bir destekleyen kurum yoktur

Teşekkür

Çalışmanın istatistiksel analizini yapmış olan Dr. Aysun Aras' a teşekkür ederiz

Kaynakça

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