Antibody Identity in Suspected Covid-19 Patients and Other Parameters

Yıl 2021, Cilt: 5 Sayı: 1, 9 - 17, 28.02.2021

Özgür Çelebi , Çiğdem Eda Balkan Bozlak , Sibel İba Yılmaz , Demet Çelebi

https://doi.org/10.33716/bmedj.861895

Öz

Aim: This study aimed to report laboratory findings of PCR and antibody research in suspect Covid-19 patients.
Materials and Methods: A total of 4206 patients with suspected Covid-19 and respiratory tract infection and 232 patients with mild clinical presentations such as cold who were admitted in hospitals were included in the study. After clinical examinations and radiological screenings, PCR tests of 4206 patients and antibody surveys of the 232 patients who were not hospitalized due to having only mild symptoms were carried out. For antibody detection, the plasmas of the EDTA-containing blood samples that were collected from the patients who were treated for Covid-19 and patients who were not treated due to having no symptoms or mild symptoms were separated and analyzed. The ‘Coronavirus disease IgM/IgG Rapid Test were used for the detection of antibodies. Antibody screenings were repeated three times 10, 17 and 24 days after the patients were diagnosed with Covid-19.
Results: The suspected Covid-19 were aged between 27 and 87 years and 2004 of the individuals were female (48%) and 2202 of the individuals were male (52%). Of 4206 plasma samples, 276 samples (6.56%) were RT-PCR-positive. Of the patients who had a positive PCR and were treated for Covid-19, 104 patients (37.68%) were female and 172 patients (62.32%) were male.
Conclusion: It is observed that death rates due to Covid-19 are more moderate in patients living in a cold climate and showing flu symptoms several times a year. Our study is in the form of some of the data of our region in order to shed light on future studies on this subject.

Anahtar Kelimeler

Covid-19, Pandemia, Patients Findings

Destekleyen Kurum

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Proje Numarası

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Teşekkür

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Covid-19 Şüphesi ile Başvuran Hastalarda Antikor Kimliği ve Diğer Parametreler

Öz

Amaç: Bu çalışma, şüpheli Covid-19 hastalarında PCR ve antikor araştırmalarının bulgularını değerlendirmeyi amaçlamaktadır.
Gereç ve Yöntemler: Çalışmaya Covid-19 ve solunum yolu enfeksiyonu şüphesiyle hastanemize başvuran toplam 4206 hasta ve soğuk algınlığı gibi hafif klinik semptomları olan 232 hasta dahil edildi. Klinik tetkikler ve radyolojik taramalar sonrasında 4206 hastanın PCR testleri ve sadece hafif semptomları nedeniyle hastaneye kaldırılmayan 232 hastanın ise antikor tetkikleri yapıldı. Antikor tespiti için Covid-19 tedavisi gören hastalardan ve hiçbir semptomu veya hafif semptomu olmadığı için tedavi edilmeyen hastalardan alınan EDTA içeren kan örneklerinin plazmaları ayrılarak analiz edildi. Antikorların tespiti için Covid-19 IgM / IgG Hızlı Test kiti kullanıldı. Antikor taramaları hastalara Covid-19 tanısı konulduktan 10, 17 ve 24 gün sonra üç kez tekrarlandı.
Bulgular: Şüpheli Covid-19 hastaları 27-87 yaşları arasındaydı. Bireylerin 2004'ü kadın (%48) ve 2202'si erkekti (%52). 4206 plazma örneğinden 276 örnek (%6,56) RT- PCR pozitifti. PCR pozitif olan ve Covid-19 tedavisi gören hastaların 104'ü (%37,68) kadın, 172'si (%62,32) erkek olarak saptandı.
Sonuç: Soğuk iklimde yaşayan ve gribal semptomları yıl içinde birkaç kez gösteren hastalarda Covid-19’ a bağlı ölüm oranlarının daha ılımlı seyrettiği görülmektedir. Çalışmamız bu konu hakkında gelecekte yapılacak çalışmalara ışık tutması amacıyla bölgemiz verilerinin bir kısmını yansıtmaktadır.

Anahtar Kelimeler

Covid-19, Pandemi, Hasta Bulguları

Proje Numarası

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Kaynakça

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