Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri

Nuran Usta; Nilgün Seremet Kürklü

doi:10.46413/boneyusbad.1657067

EN TR

Effects of Choline Supplementation During Pregnancy on Cognitive Development

Öz

Pregnancy is a period that has long-term effects on the cognitive development of the baby. During pregnancy, it is very important for the cognitive development of the fetus that pregnant women meet the guideline recommended amounts of certain macro- and micronutrients (protein, fatty acids, iron, iodine, folic acid, choline). Choline is a micronutrient that has been recognized as an essential nutrient for the human body for more than 30 years and plays a particularly important role in brain development. Choline is essential for the synthesis of phosphatidylcholine in the structure of cell membranes, sphingomyelin in the myelin sheath and acetylcholine, a critical neurotransmitter for the nervous system. Choline contributes to cognitive development by forming the structural integrity of these nervous system components. Studies show that choline supplementation during pregnancy supports fetal brain development and leads to improvements in cognitive functions such as memory, learning and attention. Inadequate daily intake of choline may adversely affect cognitive development by causing developmental disorders and neurodevelopmental damage, especially in the hippocampus and cortical regions during pregnancy and early childhood. In this context, ensuring adequate choline intake during pregnancy is critical for healthy fetal brain development.

Anahtar Kelimeler

Pregnancy, Nutrition, Choline, Cognitive Development, Supplement

Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri

Öz

Gebelik dönemi, bebeğin bilişsel gelişimi üzerinde uzun vadeli etkilere sahip bir dönemdir. Bu süreçte, gebe kadınların beslenmesinde özellikle bazı makro ve mikro besin ögelerinin (protein, yağ asitleri, demir, iyot, folik asit, kolin) rehberlerde önerilen düzeylerde alınması, bebeğin bilişsel gelişiminin desteklenmesi açısından son derece önemlidir. Kolin, 30 yılı aşkın süredir insan vücudu için temel besin ögesi olarak kabul gören ve özellikle beyin gelişimi üzerinde önemli rol oynayan bir mikro besin ögesidir. Kolin hücre zarlarının yapısında bulunan fosfotidilkolinin, miyelin kılıfta bulunan sfingomiyelinin ve sinir sistemi için kritik bir nörotransmitter olan asetilkolinin üretimi için gereklidir. Kolin, bu sinir sistemi bileşenlerinin yapısal bütünlüğünü oluşturarak bilişsel gelişime katkı sunmaktadır. Yapılan çalışmalar, gebelikte kolin takviyesinin fetal beyin gelişimini desteklediğini, hafıza, öğrenme ve dikkat gibi bilişsel işlevlerde iyileşmelere katkı sağladığını göstermektedir. Kolinin günlük yeterli düzeyde alınmaması, gebelik dönemi ve erken çocukluk döneminde özellikle hipokampus ve kortikal bölgelerde gelişimsel bozukluklara ve nörogelişimsel hasarlara neden olarak bilişsel gelişimi olumsuz etkileyebilmektedir. Bu bağlamda, gebelik döneminde yeterli kolin alımının sağlanması fetüsün sağlıklı beyin gelişimi için kritik bir öneme sahiptir.

Anahtar Kelimeler

Gebelik, Beslenme, Kolin, Bilişsel gelişim, Takviye

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Beslenme Bilimi, Gıda ve Beslenme Dengesi, Beslenme ve Diyetetik (Diğer)

Bölüm

Derleme

Yazarlar

Nuran Usta
0009-0008-4922-5864
Türkiye

Nilgün Seremet Kürklü ^*
0000-0003-1394-0037
Türkiye

Yayımlanma Tarihi

11 Ağustos 2026

Gönderilme Tarihi

13 Mart 2025

Kabul Tarihi

4 Haziran 2025

Yayımlandığı Sayı

Yıl 2026 Cilt: 8 Sayı: 2

DOI

https://doi.org/10.46413/boneyusbad.1657067

IZ

https://izlik.org/JA57NS94YC

APA

Usta, N., & Seremet Kürklü, N. (2026). Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi, 8(2), 699-709. https://doi.org/10.46413/boneyusbad.1657067

AMA

1.Usta N, Seremet Kürklü N. Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi. 2026;8(2):699-709. doi:10.46413/boneyusbad.1657067

Chicago

Usta, Nuran, ve Nilgün Seremet Kürklü. 2026. “Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri”. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi 8 (2): 699-709. https://doi.org/10.46413/boneyusbad.1657067.

EndNote

Usta N, Seremet Kürklü N (01 Ağustos 2026) Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi 8 2 699–709.

IEEE

[1]N. Usta ve N. Seremet Kürklü, “Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri”, Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi, c. 8, sy 2, ss. 699–709, Ağu. 2026, doi: 10.46413/boneyusbad.1657067.

ISNAD

Usta, Nuran - Seremet Kürklü, Nilgün. “Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri”. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi 8/2 (01 Ağustos 2026): 699-709. https://doi.org/10.46413/boneyusbad.1657067.

JAMA

1.Usta N, Seremet Kürklü N. Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi. 2026;8:699–709.

MLA

Usta, Nuran, ve Nilgün Seremet Kürklü. “Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri”. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi, c. 8, sy 2, Ağustos 2026, ss. 699-0, doi:10.46413/boneyusbad.1657067.

Vancouver

1.Nuran Usta, Nilgün Seremet Kürklü. Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri. Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi. 01 Ağustos 2026;8(2):699-70. doi:10.46413/boneyusbad.1657067

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Effects of Choline Supplementation During Pregnancy on Cognitive Development

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Gebelikte Kolin Takviyesinin Bilişsel Gelişim Üzerine Etkileri

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