ENDOMETRİAL POLİP VE TAM KAN SAYIMI PARAMETRELERİ ARASINDAKİ İLİŞKİNİN DEĞERLENDİRİLMESİ Evaluation of the Relationship Between Endometrial Polyp and Complete Blood Count Parameters

Yıl 2016, Cilt: 6 Sayı: 2, 22 - 26, 19.12.2016

Ali Seven Suna Kabil Kucur Cengiz Koçak İlay Gözükara Beril Yüksel Murat Polat Hüseyin Metineren Nadi Keskin

Öz

Amaç: Endometrial polip ile tam kan sayımı parametreleri, nötrofil/lenfosit oranı (NLR) ve trombosit/lenfosit

oranı (PLR) arasındaki ilişkiyi değerlendirmek.

Gereç ve Yöntemler: Dumlupınar Üniversitesi Kütahya Evliya Çelebi Eğitim ve Araştırma Hastanesi’nde 2014

Ocak ile 2015 Haziran ayları arasında histeroskopi (H/S) yapılan hastaların dosyaları ve patoloji sonuçları tarandı.

Çalışmaya toplam 96 hasta dahil edildi ve olgular yapılan H/S sonucunda herhangi bir endometrial patolojisi

olmayanlar (kontrol grubu, n=45) ve endometrial polipi (polip grubu, n=51) olanlar şeklinde iki gruba ayrıldı.

Gruplar arasında hemogram parametreleri, NLR ve PLR açısından karşılaştırma yapıldı. Ek olarak; polip grubu

kendi arasında polip sayısına göre iki gruba ayrılarak alt grup analizi yapıldı.

Bulgular: Kontrol grubunu ve polip grubunun ortalama trombosit hacmi (MPV) değerleri sırasıyla 8,6±0,98 ve

8,31±0,89’idi ve gruplar arasında istatistiksel anlamlı fark saptanmadı (p=0,13). Kontrol grubunun PLR değeri

138,98±60,51 iken polip grubunun 146,89±61,33 idi (p=0,52). NLR ise; kontrol grubunun 2,45±1,45, polip grubunun

2,79±2,25 (p=0,81) şeklinde idi. Gruplar arasında tam kan sayımı parametreleri, PLR ve NLR değerleri

açısından istatistiksel olarak anlamlı fark bulunmadı. Ancak; yapılan alt grup analizi sonuçlarında, 1 polipi olan

gruba göre 2 ve üzeri polipi olan grupta MPV değerleri istatistiksel olarak anlamlı yüksek bulundu (p=0,035).

Sonuç: Endometrial polip ile tam kan sayımı parametreleri, NLR ve PLR arasında anlamlı bir ilişki olmadığı

tespit edilmiştir.

ABSTRACT

Aim: To evaluate the relationship between endometrial polyp and parameters of complete blood count,

neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR).

Materials and Methods: We reviewed medical files and pathological reports of patients who underwent

hysteroscopy (H/S) procedure between January 2014 and June 2015 in Dumlupınar University Kütahya Evliya

Celebi Training and Research Hospital. Totally 96 patients were included in the study, and based on H/S

examination, the cases were classified into two groups as those who did not have any endometrial pathology

(control group, n=45) and those who had endometrial polyp (polyp group, n=51). The groups were compared

in terms of complete blood count parameters, NLR and PLR. Additionally, the polyp group was further divided

into two subgroups according to number of polyps, and the subgroups were compared with each other.

Results: Mean platelet volume (MPV) was 8.6±0.98 fL and 8.31±0.89 fL in the control and polyp groups,

respectively, and there was no statistically significant difference between the groups (p=0.13). Mean PLR value

was 138.98±60.51 in control group, and 146.89±61.33 in polyp group (p=0.52). Mean NLR value was 2.45±1.45

in control group, and 2.79±2.25 in polyp group (p=0.81). There was no statistically significant difference

between the groups regarding complete blood count parameters, PLR and NLR values. However, according the

results of subgroup analysis, MPV was significantly higher in the group with two or more polyps compared to

the group with one polyp (p=0,035).

Conclusion: In conclusion, it was determined that there was no significant relationship of endometrial polyp

with complete blood count parameters, including NLR and PLR.

Anahtar Kelimeler

Endometrial hastalıklar; Polipler; İnflamasyon; Ortalama trombosit hacmi

Kaynakça

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