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THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT'nin Rolü

Yıl 2023, Cilt: 13 Sayı: 2, 8 - 13, 15.06.2023

Öz

ABSTRACT
Objective: This study aimed to investigate the diagnostic value of positron emission tomography/computed
tomography (PET/CT) in detecting the primary focus and in suspicious foci in patients who underwent PET/
CT with a pre-diagnosis of carcinoma of unknown primary.
Material and Methods: In this retrospective study, a total of 49 patients who underwent PET/CT scan with
a prediagnosis of carcinoma of the unknown primary between 2015 and 2019, and whose clinical follow-up
and histopathological data were available, were included. PET/CT study was performed in 20 (40%) patients
after the metastatic lesion was detected as a result of pathology, and in 29 (60%) patients due to clinical
findings and imaging methods and suspicion of malignancy. The histopathological and clinical evaluation of
the patients before PET/CT and the primary surgery, histopathological examinations and clinical follow-ups
after PET/CT were examined. The success of PET/CT in detecting primary lesions and evaluating suspicious
lesions in metastatic cases was analyzed.
Results: Seventeen (34.7%) of the patients were female and 32 (65.3%) were male. A primary malignant
tumor was detected in 34 (85%) of 40 patients with PET/CT. Regional distribution in patients with primary
cancer focus; 9 pancreases, 9 lungs, 4 livers, 3 urothelial, 2 thyroids, 1 vertebra, 1 breast, 1 ovary, 1 esophagus,
1 prostate, 1 iliac bone, 1 skin, 1 stomach and 1 colon. In the follow-up of 6 cases whose primary could
not be determined; Cervical cancer was detected in 1, ovarian cancer in 1, and the primary focus could not
be detected in the clinical follow-up of 4 metastatic patients.
Conclusion: PET/CT is highly successful in detecting cancers whose primary is unknown. Therefore, PET/CT is
a diagnostic imaging method for the detection of the primary in cancer patients whose primary is unknown.

Kaynakça

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  • 2. Dermawan JK, Rubin BP. The role of molecular profiling in the diagnosis and management of metastatic undifferentiated cancer of unknown primary: Molecular profiling of metastatic cancer of unknown primary. Semin Diagn Pathol. 2021;38(6):193-8.
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  • 5. Soni N, Ora M, Aher PY, Mishra P, Maheshwarappa RP, Priya S, et al. Role of FDG PET/CT for detection of primary tumor in patients with extracervical metastases from carcinoma of unknown primary. Clin Imaging. 2021;78:262-70.
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  • 7. Stares M, Purshouse K, Knowles G, Haigh R, Irvine J, Gatenby A, et al. Characterisation and outcomes of patients referred to a regional cancer of unknown primary team: a 10-year analysis. Br J Cancer. 2021;125(11):1503-10
  • 8. Fizazi K, Greco FA, Pavlidis N, Daugaard G, Oien K, Pentheroudakis G, et al. Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol.2015;26 Suppl 5:v133–8.
  • 9. Pavlidis N, Fizazi K. Carcinoma of unknown primary (CUP). Crit Rev Oncol Hematol. 2009;69(3):271-8.
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Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Nükleer Tıp
Bölüm Orjinal Çalışma
Yazarlar

Ozan Kandemır Bu kişi benim

Fadime Kandemir Bu kişi benim

Yayımlanma Tarihi 15 Haziran 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 13 Sayı: 2

Kaynak Göster

APA Kandemır, O., & Kandemir, F. (2023). THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü. Bozok Tıp Dergisi, 13(2), 8-13.
AMA Kandemır O, Kandemir F. THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü. Bozok Tıp Dergisi. Haziran 2023;13(2):8-13.
Chicago Kandemır, Ozan, ve Fadime Kandemir. “THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü”. Bozok Tıp Dergisi 13, sy. 2 (Haziran 2023): 8-13.
EndNote Kandemır O, Kandemir F (01 Haziran 2023) THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü. Bozok Tıp Dergisi 13 2 8–13.
IEEE O. Kandemır ve F. Kandemir, “THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü”, Bozok Tıp Dergisi, c. 13, sy. 2, ss. 8–13, 2023.
ISNAD Kandemır, Ozan - Kandemir, Fadime. “THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü”. Bozok Tıp Dergisi 13/2 (Haziran 2023), 8-13.
JAMA Kandemır O, Kandemir F. THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü. Bozok Tıp Dergisi. 2023;13:8–13.
MLA Kandemır, Ozan ve Fadime Kandemir. “THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü”. Bozok Tıp Dergisi, c. 13, sy. 2, 2023, ss. 8-13.
Vancouver Kandemır O, Kandemir F. THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT’nin Rolü. Bozok Tıp Dergisi. 2023;13(2):8-13.
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