Mind and Body: Neuropsychological Foundations and Interactions Between Organs

Öz

This article focuses on understanding the neuropsychological foundations of the mind by exploring topics such as the mind-body problem, neuroscience, neuronal structures, brain-mind relationship, heart-mind connection, and gut-mind interactions.The historical evolution of the concept of the mind has been examined from philosophical perspectives to advances in neuroscience.The functions of the mind, including decision-making, learning, and problem-solving, are analyzed in detail, with an emphasis on their neurological basis.While the brain is considered the central organ for mental functions, the influence of other organs, such as the heart and gut, on mental processes has also been highlighted.The heart is presented as a guiding center for emotional and cognitive processes, whereas the gut-brain axis plays a significant role in mental health and cognitive function.This article provides a multidisciplinary approach to understanding the concept of the mind and establishes a foundation for future studies.

Anahtar Kelimeler

• Mind
• Neuroscience
• Neuropsychology
• Brain
• Heart
• Gut

Akıl ve Beden: Nöropsikolojik Temeller ve Organlar Arası Etkileşimler

Öz

Bu inceleme, aklın nöropsikolojik temellerini anlamak amacıyla akıl-beden problemi, nörobilim, nöronal yapılar, beyin-akıl ilişkisi, kalp-akıl ilişkisi ve bağırsak-akıl ilişkisi gibi konulara odaklanmaktadır. Akıl kavramının tarihsel evrimi, felsefi düşünce akımlarından nörobilimdeki ilerlemelere kadar geniş bir perspektifte ele alınmıştır. Aklın işlevleri, bireyin seçim yapma, karar verme, öğrenme ve problem çözme yeteneklerini kapsamakta olup, bu süreçlerin nörolojik temelleri detaylı bir şekilde incelenmiştir. Beyin, akıl işlevlerinin merkezi olarak ele alınırken, kalp ve bağırsak gibi diğer organların da zihinsel süreçler üzerindeki etkileri vurgulanmıştır. Kalbin, duygusal ve düşünsel süreçlerde rehberlik eden bir merkez olduğu, bağırsak-beyin ekseninin ise zihinsel sağlık ve bilişsel işlevler üzerinde önemli bir rol oynadığı ortaya konulmuştur. Bu inceleme, akıl kavramını anlamak için multidisipliner bir yaklaşım sunmakta ve gelecekteki araştırmalar için bir temel oluşturmaktadır.

Anahtar Kelimeler

• Akıl
• Nörobilim
• Nöropsikoloji
• Beyin
• Kalp
• Bağırsak

Kaynakça

1. Adams, J. B., Johansen, L. J., Powell, L. D., Quig, D. ve Rubin, R. A. (2011). Gastrointestinal flora and gastrointestinal status in children with autism: comparisons to typical children and correlation with autism severity. BMC gastroenterology, 11(1), 1-13. doi: 10.1186/1471-230X-11-22.
2. Alshami, A. M. (2019). Pain: Is it all in the brain or the heart. Current Pain and Headache Reports, 23, 1-4.doi: 10.1007/s11916-019-0827-4.
3. Amerikan Psikiyatri Birliği (2013) Ruhsal bozuklukların tanısal ve sayımsal elkitabı, beşinci baskı (DSM-5), Tanı Ölçütleri Başvuru El kitabı (E Köroğlu, çev.). Ankara: Hekimler Yayın Birliği.
4. Anderberg, R. H., Hansson, C., Fenander, M., Richard, J. E., Dickson, S. L., Nissbrandt, H., … Skibicka, K. P. (2016). The stomach-derived hormone, ghrelin, increases impulsive behavior. Neuropsychopharmacology, 41(5), 1199-1209. doi: 10.1038/npp.2015.297.
5. Antonini, M., Lo Conte, M., Sorini, C., & Falcone, M. (2019). How the interplay between the commensal microbiota, gut barrier integrity, and mucosal immunity regulates brain autoimmunity. Frontiers in immunology, 10, 1937.doi: 10.3389/fimmu.2019.01937.
6. Armour, J. A. ve Ardell, J. L. (Ed.). (2004). Basic and Clinical Neurocardiology. New York: Oxford University Press. Atkinson, R. L., Atkinson, R. C., Smith, E. E., Bem, D. J. ve Nolen-Hoeksema, S. (2010). Psikolojiye giriş (Y. Alogan, çev.) (2. Baskı). Ankara: Arkadaş Yayınevi.
7. Baig, M. N., Chishty, F., Immesoete, P., & Karas, C. S. (2007). The Eastern heart and Galen's ventricle: a historical review of the purpose of the brain. Neurosurgical Focus, 23(1), 1-6. https://doi.org/10.3171/FOC-07/07/E3.
8. Banikowski, A. K., & Mehring, T. A. (1999).Strategies to enhance memory based on brain research. Focus on Exceptional Children, 32(2), 1-16. https: //doi.org/10. 17161/ foec. v32i2.6772.

9. Beaumont, J. G. (2008). Introduction to Neuropsychology.New YORK: Guilford Press.
10. Bechara, A., Damasio, H., & Damasio, A. R. (2000). Emotion, decision-making, and the orbitofrontal cortex.Cerebral Cortex, 10(3), 295-307. https:// doi: 10. 1093 /cercor/ 10.3.295. Berhouma, M. (2013). Beyond the pineal gland assumption: A neuroanatomical appraisal of dualism in Descartes’ philosophy. Clinical neurology and neurosurgery, 115(9), 1661-1670. https://doi.org/10.1016/j.clineuro.2013.02.023.
11. Bergson, H. (2020). Ruh teorileri, ı̇nsan ruhu ve kişiliği (E.B. Altıntas, çev.). İstanbul: Pinhan Yayıncılık.
12. Björklund, A., & Dunnett, S. B. (2007). Dopamine neuron systems in the brain: an update. Trends in Neurosciences, 30(5), 194- 202. DOI: https://doi: 10.1016/j.tins.2007.03.006.
13. Bloom, F. E. (2006). Neurotransmission in the central nervous system. Goodman and Gilman: The pharmacological basis of therapeutics. McGraw Hill, New York, NY, 317-339.
14. Bolay, S.H. (1989). Türkiye Diyanet Vakfı İslam Ansiklopedisi.2. İstanbul: TDV Yayınları.
15. Churchland, P. M. (2012). Madde ve bilinç. (B. Ersöz, çev.). İstanbul: Alfa Yayınları.
16. Cools, R., Nakamura, K., & Daw, N. D. (2011). Serotonin and dopamine: Unifying affective, activational, and decision functions. Neuropsychopharmacology, 36(1), 98-113. https://doi: 10.1038/npp.2010.121. Cope, E. C., & Gould, E. (2019). Adult neurogenesis, glia, and the extracellular matrix. Cell Stem Cell, 24(5), 690-705.https://doi.org/10.1016/j.stem.2019.03.023.
17. Cowan, W. M. (1979). The development of the brain. Scientific American, 241(3), 112-133. doi:10.1038/scientificamerican0979-112.
18. Crockett, M. J. & Fehr, E. (2014).Pharmacology of economic and social decision-making. In P.W. Glimcher, E. Fehr (Eds.), Neuroeconomics (pp. 259-279). London: Academic Press. https://doi.org/10.1016/B978-0-12-416008-8.00014-0.
19. Cryan, J. F. ve Dinan, T. G. (2012). Mind-altering microorganisms: the impact of the gut microbiota on the brain and behavior. Nature reviews neuroscience, 13(10), 701-712. https://doi.org/10.1038/nrn3346.
20. Curcio, M. & Bradke, F. (2018). Axon regeneration in the central nervous system: facing the challenges from the inside. Annual review of cell and developmental biology, 34, 495-521. https://doi.org/10.1146/annurev-cellbio-100617-062508.
21. Çiftçi, H. (2023). Yahudilik, hıristiyanlık, sabiilik ve çeşitli mitolojilerde akılla ilgili kavramlar ve figürler. T. Akyüz (Ed.) Akıl Kitabı 9 içinde (s. 47-72). istanbul: Ravza.
22. D'Arcangelo, M. (2000). How does the brain develop? A conversation with Steven Petersen.Educational leadership, 58(3), 68-71.
23. Dahlin, M., Elfving, Å., Ungerstedt, U., & Åmark, P. (2005). The ketogenic diet influences the levels of excitatory and inhibitory amino acids in the CSF in children with refractory epilepsy. Epilepsy research, 64(3), 115-125.https: //doi.org/10.1016/j.eplepsyres. 2005. 03. 008.
24. Dalrymple, J. B. (2004). Teaching and learning law with graphic organizers. Diakses dari www. loyno. edu/~ dciolino/classes htm.
25. Demir H (2009) Aklı geliştirmenin yolları. İstanbul: Beyin Gücü.
26. Devanand, D. P. (2001). The memory program: How to prevent memory loss and enhance memory power. New York: John Wiley&Sons Inc.
27. Dinan, T. G. ve Cryan, J. F. (2015). The impact of gut microbiota on the brain and behavior: Implications for psychiatry. Current Opinion in Clinical Nutrition & Metabolic Care, 18(6), 552-558.doi: 10.1097/MCO.0000000000000221.
28. Dinan, T. G., Stanton, C. ve Cryan, J. F. (2013). Psychobiotics: a novel class of psychotropic. Biological psychiatry, 74(10), 720-726. https://doi.org/10.1016/j. biopsych.2013.05.001.
29. El Maturidi, E. M. (1979). Kitabü't tevhid. (F. Huleyf, çev.). İstanbul: El Mektebetü'l-İslamiyye.
30. El-Muhâsibî, H. (2004). El-Akl ve fehmü'l kur'an akıl ve Kur'an'ın anlaşılması, (V. Akdoğan, çev.). İstanbul: İşaret Yayınları.
31. Felice, V. D., Quigley, E. M., Sullivan, A. M., O'Keeffe, G. W. ve O'Mahony, S. M. (2016). Microbiota-gut-brain signalling in Parkinson's disease: Implications for non-motor symptoms. Parkinsonism & related disorders, 27, 1-8. doi: 10.1016/ j.parkreldis. 2016.03.012.
32. Fiş, N. P. Ve Berkem, M. (2009). Nörotransmitter Sistemlerinin Gelişimi ve Psikopatolojiye Yansımaları. Klinik Psikofarmakoloji Bulteni, 19(3).
33. Frith, C., & Frith, U. (2005). Theory of mind. Current biology, 15(17), R644-R645. https://doi.org/10.1016/j.cub.2005.08.041.
34. Foster-Deffenbaugh, L. A. (1996). Brain research and its implications for educational practice. Unpublished Doctoral Dissertation. Brigham Young University.
35. Francini, A. (2008). Consciousness, mind, and intelligence: Some research and notes. The Rose Croix Journal, 5, 1-14.
36. Freemon, F. R. (1994). Galen's ideas on neurological function. Journal of the History of the Neurosciences, 3(4), 263-271.doi: 10.1080/09647049409525619.
37. Foreman, R. D., Garrett, K. M., & Blair, R. W. (2011). Mechanisms of cardiac pain. Comprehensive Physiology, 5(2), 929-960.https://doi.org/10.1002/cphy.c140032.
38. Furness, J. B. (2008). The enteric nervous system. Massachusetts: Blackwell Publishing. Furness, J. B., Kunze, W. A. A., Bertrand, P. P., Clerc, N. ve Bornstein, J. C. (1998). Intrinsic primary afferent neurons of the intestine. Progress in neurobiology, 54(1), 1-18. https://doi.org/10.1016/s0301-0082(97)00051-8.
39. Georgy B. A., Hesselink J. R. ve Jernigan, T. L. (1993). MR imaging of the corpus callosum. AJR. American journal of roentgenology, 160(5), 949-955. https://doi.org /10.2214/ajr.160.5.8470609.
40. Gershon, M. D. (1999). The enteric nervous system: A second brain.Hospital practice, 34(7), 31-52. https://doi.org/10.3810/hp.1999.07.153.
41. Girard, D. (1965). Cassell’s New French-English Dictionary. London: Cassell & Co. Ltd.
42. Goldberg, E. (2001). The executive brain: Frontal lobes and the civilized mind. New York: Oxford University Press.
43. Goldstein, D. S. (2010). Neuroscience and heart-brain medicine: A year in review.Clevel and Clinic journal of medicine, 77(0 3), S34. doi:10.3949/ccjm.77.s3.06.
44. Gündoğar, D. &Demirci, S. (2007). Konfabulasyon (Masallama): İlgi çeken ancak yeterince bilinmeyen bir belirti. Türk Psikiyatri Dergisi, 18(2), 172-178. https://www.turkpsikiyatri.com/Data/UnpublishedArticles/konfabulasyonIlgi.pdf.
45. Heijtz, R. D.,Wang, S., Anuar, F., Qian, Y., Björkholm, B., Samuelsson, A. ve Pettersson, S. (2011). Normal gut microbiota modulates brain development and behavior. Proceedings of the National Academy of Sciences, 108(7), 3047-3052. https://doi.org/10.1073/pnas.1010529108.
46. Hormuzdi, S. G., Filippov, M. A., Mitropoulou, G., Monyer, H. ve Bruzzone, R. (2004). Electrical synapses: A dynamic signaling system that shapes the activity of neuronal networks. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1662(1-2), 113-137. https://doi.org/10.1016/j.bbamem.2003.10.023.
47. Hu, H., & Spencer, N. J. (2018). Enteric Nervous System Structure and Neurochemistry Related to Function and Neuropathology. In H. M. Said (Eds.), Physiology of the Gastrointestinal Tract: Sixth Edition (6th ed., Vol. 1-2, pp. 337-360). Elsevier/Academic Press. https://doi.org/10.1016/B978-0-12-809954-4.00014-1.
48. Hume, D. (2017). İnsanın anlama yetisi üzerine bir soruşturma (F.B. Aydar, çev.). İstanbul: Türkiye İş Bankası Yayınları.
49. Ingram, R. E., & Siegle, G. J (2010). Cognitive science and the conceptual foundations of cognitive-behavioral therapy. In K. S. Dobson (Eds.) Handbook of Cognitive-Behavioral Therapies (3rd ed.) (pp. 74-93). New York:Guilford Press
50. Isaacson, R. (2013). The limbic system. New York: Springer Science and Business Media.
51. John, S. E., Ritter, A., Wong, C. ve Parks, C. M. (2022). The roles of executive functioning, simple attention, and medial temporal lobes in early learning, late learning, and delayed recall. Aging, Neuropsychology, and Cognition, 29(3), 400-417. https: //doi.org /10.1080/13825585.2021.2016583.
52. Kandel, E. R.,Schwartz, J. H., Jessell, T. M., Siegelbaum, S., Hudspeth, A. J. ve Mack, S. (Eds.) (2000). Principles of Neuroscience (Vol. 4, pp. 1227-1246). New York: McGraw-hill.
53. Kauffman, S. A. ve Roli, A. (2023). What is consciousness? Artificial intelligence, real intelligence, quantum mind, and qualia. Biological Journal of the Linnean Society, 139(4), 530-538.https://doi.org/10.1093/biolinnean/blac092.
54. Keleş, E. ve Çepni, S. (2006). Beyin ve öğrenme. Journal of Turkish Science Education, 3(2), 66-82. https://www.tused.org/index.php/tused/article/view/494.
55. Kelly, D. R. (2017). The descent of ıdeas: the history of ıntellectual history. New York: Routledge.
56. Kennerley, S. W., Walton, M. E., Behrens, T. E., Buckley, M. J. ve Rushworth, M. F. (2006). Optimal decision-making and the anterior cingulate cortex.Nature neuroscience, 9(7), 940-947. https://doi.org/10.1038/nn1724.
57. Kenwood M. M., Kalin N. H. ve Barbas, H. (2022). The prefrontal cortex, pathological anxiety, and anxiety disorders:Neuropsychopharmacology, 47(1), 260-275. https://doi: 10.1038/s41386-021-01109-z.
58. Kitamura, T. & Inokuchi, K. (2014). Role of adult neurogenesis in hippocampal-cortical memory consolidation. Molecular brain, 7(1), 1-8.https://doi.org/10.1186/1756-6606-7-13.
59. Koca O. &Dönmez, N. (2020). İkinci beyin: Bağırsak. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 15(2), 187-195. https://doi.org/10.17094/ataunivbd.701620.
60. Kolb, B. Whishaw, I. Q.(1990). Fundamentals of human neuropsychology (3.Baskı).New York: W.H. Freeman and Company.
61. Krawczyk, D. C. (2002). Contributions of the prefrontal cortex to the neural basis of human decision-making.Neuroscience & Biobehavioral Reviews, 26(6), 631-664. https://doi: 10.1016/s0149-7634(02)00021-0.
62. Kullmann, D. M. (2011). Interneuron networks in the hippocampus.Currentopinion in neurobiology, 21(5), 709-716. https://doi.org/10.1016/j.conb.2011.05.006.
63. Lallemend, F. Ve Ernfors, P. (2012). Molecular interactions underlying the specification of sensory neurons.Trends in neurosciences, 35(6), 373-381. https://doi.org/10.1016/ j.tins.2012.03.006.
64. Lamar, M. (2006, June). Neuroscience and decision-making.In Presentation at the " improving the decision-taking process in Institutions" workshop, London School of Economics.https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=297ad4064ce41f39bb55d044419524da7f9a2ca7.
65. Legg, S. & Hutter, M. (2007). A collection of definitions of intelligence. Frontiers in Artificial Intelligence and applications, 157, 17-24.
66. Lektorsky, V. (1998). Özne, nesne, biliş (Ş. Alpagut, çev.). İstanbul: Toplumsal Dönüşüm Yayınları.
67. Lewis, G. R. (1993). Descartes ve rasyonalizm (H. Karyol, çev.) İstanbul: İletişim.
68. Lezak, M. D. (2004). Neuropsychological assessment. New York: Oxford University Press.
69. Locke, J. (1992). İnsan anlığı üzerine bir deneme (V. Hacıkadiroğlu, çev.). İstanbul: Kabalcı Yayınevi.
70. Long, A. B., Kuhn, C. M. Ve Platt, M. L. (2009). Serotonin shapes risky decision-making in monkeys.Social Cognitive and Affective Neuroscience, 4(4), 346-356. https://doi: 10.1093/scan/nsp02.
71. Luciana, M., Burgund, E. D., Berman, M., & Hanson, K. L. (2001).Effects of tryptophan loading on verbal, spatial, and affective working memory functions in healthy adults. Journal of Psychopharmacology, 15(4), 219-230. https://doi.org/10.1177/ 026988110101500410.
72. McCraty, R., & Atkinson, M. (2014).Electrophysiology of intuition: Pre-stimulus responses in group and individual participants using a roulette paradigm. Global advances in health and medicine, 3(2), 16-27. https://doi.org/10.7453/gahmj.2014.01.
73. McCraty, R., Atkinson, M., Tomasino, D., &Bradley, R. T. (2009). The coherent heart: Heart–brain interactions, psychophysiological coherence, and the emergence of system-wide order. Integral Review, 5(2), 10–115. https://doi.org/10.1016/j.cub.2005.08.041.
74. McCraty, R. ve Shaffer, F. (2015). Heart rate variability: new perspectives on physiological mechanisms, assessment of self-regulatory capacity and health risk. Global advances in health and medicine, 4(1), 46-61. https://doi.org/10.7453/gahmj.2014.073.
75. McFadden, K. S. (2001). An investigation of attitudes, anxiety, and achievement of college algebra students using brain-compatible teaching techniques. Unpublished Doctoral Dissertation. Tennessee State University, Tennessee, USA.
76. McKay, R. (1997). Stem cells in the central nervous system. Science, 276(5309),6671.doi:10.1126/science.276.5309.66.
77. Meneses, A. & Liy-Salmeron, G. (2012).Serotonin, emotion, learning, and memory. Reviews in the Neurosciences, 23(5-6), 543-553. https://doi.org/ 10.1515/revneuro-2012-0060.
78. Minter, M. R., Zhang, C., Leone, V., Ringus, D. L., Zhang, X., Oyler-Castrillo, P., ...Sisodia, S. S. (2016). Antibiotic-induced perturbations in gut microbial diversity influence neuroinflammation and amyloidosis in a murine model of Alzheimer’s disease. Scientific reports, 6(1), 30028. https://doi.org/10.1038/srep30028.
79. Mirsky, A. F. ve Duncan, C. C. (2001). A nosology of disorders of attention. Annals of the New York Academy of Sciences, 931(1), 17-32.https://doi.org/10.1111/j.1749-6632.2001.tb05771.x.
80. Öktem, Ö. (1994) Nöropsikolojik testler ve nöropsikolojik değerlendirme. Türk Psikoloji Dergisi, 9(33), 33-44.
81. Özen, Y. ve Gülaçtı, F. (2023). Aklın Etiyolojisinden Epistemolojisine1 (Batı-Doğu Arasında Aklın Halleri). Ö. Baltacı (Eds.), Eğitim Bilimleri Araştırmaları-II içinde (s.1-30). Gaziantep: Özgür Yayınları.
82. Parvizi, J. ve Damasio, A. (2001). Consciousness and the brainstem. Cognition, 79(1-2), 135-160.https://doi.org/10.1016/S0010-0277(00)00127-X.
83. Paulson S. (2013).The emerging science of consciousness: Mind, brain, and the human experience. Annals of the New York Academy of Sciences, 1303(1), 1-3.https://doi.org/10.1111/nyas.12301.
84. Peters, F. E. (2004). Antik yunan terimleri sözlüğü (H. Hünler, çev.). İstanbul: Paradigma Yayınları.
85. Piazza, M. (2020). Maine de Biran and Gall’s phrenology: the origins of a debate about the localization of mental faculties. British Journal for the History of Philosophy, 28(5), 866884.https://doi.org/10.1080/09608788.2020.1760785.
86. Pinker, S. (2016). Boş sayfa (M. Doğan, çev.) (3.Baskı). İstanbul: Boğaziçi Üniversitesi Yayınları.
87. Pinkerton, K. D. (1994). Using brain-based learning techniques in high school science: Teaching and Change, 2(1), 44-60.
88. Rajmohan, V., & Mohandas, E. (2007). The limbic system. Indian journal of psychiatry, 49(2), 132. doi: 10.4103/0019-5545.33264.
89. Ratcliff, R. ve Rouder, J. N. (1998). Modeling response times for two-choice decisions. Psychological Science, 9(5), 347-356. https://doi.org/10.1111/1467-9280.00067.
90. Robinson, R. (1942). Plato's consciousness of fallacy. Mind, 51(202), 97-114.
91. Roffman, J. L., Tanner, A. S., Eryilmaz, H., Rodriguez-Thompson, A., Silverstein, N. J., Ho, N. F., … Catana, C. (2016) Dopamine D1 signaling organizes network dynamics underlying working memory. Science advances, 2(6), e1501672. https://doi: 10.1126/sciadv.15016.
92. Rogers, R. D. (2011). The roles of dopamine and serotonin in decision-making: Evidence from pharmacological experiments in humans.Neuropsychopharmacology, 36(1), 114-132. https://doi: 10.1038/npp.2010.165.
93. Rolls, E. T. (2015). Limbic systems for emotion and for memory, but no single limbic system. Cortex, 62, 119-157.https://doi.org/10.1016/j.cortex.2013.12.005.
94. Roshchina, V.V. (2010). Evolutionary considerations of neurotransmitters in microbial, plant, and animal cells. In Lyte, M. & Freestone, P. (Eds.) Microbial Endocrinology (pp.17-55). New York: Springer. https://doi.org/10.1007/978-1-4419-5576-0.
95. Rudorf, S. & Hare, T. A. (2014). Interactions between dorsolateral and ventromedial prefrontal cortex underlie contextdependent stimulus valuation in goal-directed choice. Journal of Neuroscience, 34(48), 15988-15996. https://doi: 10.1523/JNEUROSCI.3192-14.2014.
96. Sakai, J. (2020). How synaptic pruning shapes neural wiring during development and possibly in disease.Proceedings of the National Academy of Sciences, 117(28), 16096-16099.https://doi.org/10.1073/pnas.2010281117.
97. Saraiva, A. C., & Marshall, L. (2015). Dorsolateral–ventromedial prefrontal cortex interactions during value-guided choice: A function of context or difficulty? Journal of Neuroscience, 35(13), 5087-5088. https://doi: 10.1523/JNEUROSCI.0271- 15.2015.
98. Schandry, R. ve Montoya, P. (1996). Event-related brain potentials and the processing of cardiac activity. Biological psychology, 42(1-2), 75-85.https://doi.org/10.1016/0301-0511(95)05147-3.
99. Schnaitter, R. (1985). The haunted clockwork: Reflections on Gilbert Ryle's The concept of mind. Journal of the Experimental Analysis of Behavior, 43(1), 145. doi: 10.1901/jeab.1985.43-145.
100. Schultz, W. (2007). Behavioral dopamine signals. Trends in Neurosciences, 30(5), 203-210. https://doi: 10.1016/j.tins.2007.03.007.
101. Shaffer, F.,McCraty, R. ve Zerr, C. L. (2014). A healthy heart is not a metronome: an integrative review of the heart’s anatomy and heart rate variability.Frontiers in psychology, 5, 1040. https://doi.org/10.3389/fpsyg.2014.01040.
102. Shaffere A. J. (1991). Bilinç, ruh ve ötesi (T. Koç, çev.). İstanbul: İz yayıncılık.
103. Shapiro, L. (2011). Descartes's Pineal Gland Reconsidered. Midwest Studies In Philosophy, 1(35), 259-286. https://doi.org/10.1111/j.1475-4975.2011.00219.x.
104. Shipp, S. (2007). Structure and function of the cerebral cortex. Current Biology, 17(12), R443-R449.
105. Siju, K. P., Štih, V., Aimon, S., Gjorgjieva, J., Portugues, R. ve Kadow, I. C. G. (2020). Valence- and state-dependent population coding in dopaminergic neurons in the fly mushroom body.Current Biology, 30(11), 2104-2115. https://doi:10.1016/j.cub.2020. 04.03.
106. Song, I., & Dityatev, A. (2018).Crosstalk between glia, extracellular matrix, and neurons. Brain research bulletin, 136, 101-108. https://doi.org/10.1016/ j.brainresbull. 2017.03.003.
107. Soysal A., Kılıç, K. ve Karakaş, S. (2005). Temporal lobun sesi: müzik. Yeni Symposıum: Psikiyatri. Nöroloji Ve Davranış Bilimleri Dergisi, 43(3), 107-113.
108. Strick, P. L., Dum, R. P. ve Fiez, J. A. (2009). Cerebellum and non-motor function. Annual review of neuroscience, 32, 413-434. https://doi.org/10.1146/annurev.neuro.31. 060407. 125606.
109. Tanaka, K. Z., Pevzner, A., Hamidi, A. B., Nakazawa, Y., Graham, J., … Wiltgen, B. J. (2014). Cortical representations are reinstated by the hippocampus during memory retrieval. Neuron, 84(2), 347-354.http://dx.doi.org/10.1016%2Fj.neuron.2014.09.037.
110. Tarazi, F. I., & Baldessarini, R. J. (2000). Comparative postnatal development of dopamine D1, D2, and D4 receptors in rat forebrain. International Journal of Developmental Neuroscience, 18(1), 29-37. https://doi.org/10.1016/S0736-5748(99)00108-2.
111. Tarlaci, S. (2019). Bilinc: beyin, zihin ve benligin kesfi. İstanbul: Destek Yayınları.
112. Taylor, K. ve Lamoreaux, A. (2008). Teaching with the brain in mind. New directions for adult and continuing education, 119(fall), 49-59.
113. Toga, A. W. &Thompson, P. M. (2005). Genetics of brain structure and intelligence. Annu. Rev. Neurosci, 28, 1-23. https://doi.org/10.1146/annurev.neuro.28.061604.135655.
114. Tuna, D. G. E., & Cabıoğlu, D. M. T. (2022). Bütünsel bakış açısıyla kalp-beyin-bağırsak aksı: ateş elementi. Ankara Akupunktur ve Tamamlayıcı Tıp Dergisi,10 (1) : 8-12.
115. Ulaş, S. E. (2002). Felsefe sözlüğü. Ankara: Bilim ve Sanat Yayınları.
116. Uluorta, N. & Atabek, E. (2003). Beyin eğitimi ve fen bilgisi lavoratuvar öğretimindeki yeri. Sakarya Üniversitesi Eğitim Fakültesi Dergisi, (6). https://dergipark.org.tr/en/pub/ sakaefd/issue/11225/134010.
117. Ungerleider, L. G., & Haxby, J. V. (1994). ‘What’and ‘where’in the human brain. Current opinion in neurobiology, 4(2), 157-165. https://doi.org/10.1016/0959-4388(94)90066-3.
118. Uriarte C., Cañeque, S. T. ve Sunal, C. B (2010) Diccionario turco español. Navalcarnero : Ediciones Akal, S.A.
119. Uzbay, İ. T. (2015). Beyni anlamak sadece nörobilim ile mümkün mü? Beyin yüzyılında nörolojik bilimlerden sosyal bilimlere yeni açılımlar, yeni yaklaşımlar. Üsküdar Üniversitesi Sosyal Bilimler Dergisi, (1), 119-155.https://doi.org/10.32739/ uskudarsbd. 1.1.12.
120. Ülkü, V. (2005) Büyük Almanca- Türkçe Sözlük. İstanbul: İnkılap Yayınevi.
121. Venkatraman, A., Edlow, B. L., & Immordino-Yang, M. H. (2017). The brainstem in emotion: a review. Frontiers in neuroanatomy, 11, 15. https://doi.org/10.3389/ fnana.2017.00015.
122. Vertes, R. P., Linley, S. B. ve Hoover, W. B. (2015). Limbic circuitry of the midline thalamus. Neuroscience & Biobehavioral Reviews, 54, 89-107. https://doi.org/10.1016/ j.neubiorev.2015.01.014.
123. Vygotsky, L. S. (1998). Düşünce ve dil (S. Koray, çev.) (2.Baskı). İstanbul: Toplumsal Dönüşüm Yayınları.
124. Walsh, K. (1987). Neuropsychology: A clinical approach (2nd ed.). Melborne: Churchill Livingstone.
125. Wang, X. J. (2008). Decision-making in recurrent neuronal circuits.Neuron, 60(2), 215-234. https://doi: 10.1016/j.neuron.2008.09.034.
126. Webster, M. (1986). Webster’s third new international dictionary. New York: Merriam-Webster.
127. Weintraub, S. & Mesulam, M-M. (1985) Mental state assessment of young and elderly adults in behavioral neurology. In M-M. Mesulam (Eds.) Principles of Behavioral Neurology (pp. 71-168). Philadelphia: F. A. Davis Company.
128. Weiss, R. P. (2000). Brain Based Learning. Training & Development, 54(7), 21.
129. White, N. P. (1976). Plato on knowledge and reality. Cambridge: Hackett Publishing.
130. Whitney, A. (2017). Map of the heart: An east-west understanding of heart intelligence and its application in counseling psychology. Unpublished Doctoral Dissertation. California Institute of Integral Studies. California.
131. Williams, E. K., Chang, R. B., Strochlic, D. E., Umans, B. D., Lowell, B. B…Liberles, S. D. (2016). Sensory neurons that detect stretch and nutrients in the digestive system. Cell, 166(1), 209-221. http://dx.doi.org/10.1016/j.cell.2016.05.011.
132. Wolfe, P. (2010). Brain matters: Translating research into classroom practice (2.Baskı). Alexandria: ASCD.
133. Wortock, J. M. M. (2002).Brain-based learning principles applied to the teaching of basic cardiac code to associate degree nursing students using a human patient simulator. Unpublished Doctoral Dissertation. University of South Florida, Florida, USA.
134. Ziylan, T. Ve Murshid, K. A. (2000). Korteksin anatomik yapısı ve fonksiyonel alanları. Genel Tıp Dergisi, 10(2), 87-91.
135. Zola-Morgan, S. (1995). Localization of brain function: The legacy of Franz Joseph Gall (1758-1828). Annual review of neuroscience, 18(1), 359-383. https://doi.org/10.1146/ annurev.ne.18.030195.002043.