INVESTIGATION OF THE EFFECT OF FLUCTUATIONS IN ESTROPEN LEVELS DUE TO MENSTRUAL CYCLE ON BONE MINERALS DENSITY

Öz

The effect of the change in estrogen hormone related to the menstrual cycle on bone mineral density was investigated. The study consisted of 23 physically active young women with a mean age of 20.65±1.87 years, 1.62±0.06 height, 55.61±8.805 kg. After the menstrual cycle phases were determined, bone mineral density (BMD) (T score of the vertebrae L1-L4 and femoral neck regions and BMD (g/cm2) values) were measured in each phase. The obtained data was used in the SPSS 21.0 package program, with repeated measures analysis of variance (ANOVA). The confidence interval was chosen as 95% and values below p<0.05 were considered statistically significant. It was determined that the mean of the interphase mean of the T score and BMD (g/cm2) values of the vertebra L1-L4 and femoral neck regions of the participants did not differ according to time. However, when the T score values of the regions were examined, it was determined that the L1-L4 region and the femur length had the lowest mean in the middle luteal phase compared to the other phases. When the BMD (g/cm2) values were compared, it was found that L1-L4 had the lowest mean in the middle luteal, while the femur length had the lowest mean in the ovulation and middle luteal phases compared to the other phases. It is suggested that some phases of the menstrual cycle in young women affect bone mineral density and that calcium supplements should be used during these periods for bone health..

Anahtar Kelimeler

• Östrojen
• Kemik mineral yoğunluğu
• Menstrual döngü.

MENSTRUEL DÖNGÜYE BAĞLI ÖSTROJEN SEVİYELERİNDEKİ DALGALANMALARIN KEMİK MİNERAL YOĞUNLUĞU ÜZERİNE ETKİSİNİN ARAŞTIRILMASI

Öz

Menstruel döngüye bağlı östrojen hormonundaki değişimin kemik mineral yoğunluğu üzerine etkisi incelenmiştir. Araştırma ortalama yaşı 20.65±1.87 yıl, 1.62±0.06 boy, 55.61±8.805 kg olan fiziksel olarak aktif 23 genç kadından oluşmaktadır. Adet döngü fazları belirlendikten sonra her fazda katılımcılardan kemik mineral yoğunluğu (KMY) (vertebra L1-L4 ve femur boyun bölgelerinin T skoru ile KMY(g/cm2) değerleri) düzeyleri ölçülmüştür. Elde edilen verilere SPSS 21.0 paket programında tekrarlı ölçümlerde varyans analizi (Repeated measures -ANOVA) kullanılmıştır. Güven aralığı %95 olarak seçilmiş ve p<0,05’in altındaki değerler istatiksel olarak anlamlı kabul edilmiştir. Katılımcıların vertebra L1-L4 ile femur boyun bölgelerinin T skoru ile KMY(g/cm2) değerlerinin fazlar arası ortalamalarının zamana göre farklılık göstermediği tespit edilmiştir. Ancak bölgelerin T skoru değerleri incelendiğinde L1-L4 bölgesi ile femur boyunun orta luteal fazda diğer fazlara oranla en düşük ortalamaya sahip olduğu tespit edilmiştir. KMY(g/cm2) değerlerinin karşılaştırılmasına bakıldığında ise L1-L4’ün orta lutealde, femur boyunun ise ovülasyon ve orta luteal fazın diğer fazlara oranla en düşük ortalamaya sahip olduğu bulunmuştur. Genç kadınlarda menstruel döngüdeki bazı fazların kemik mineral yoğunluğunu etkilediği ve kemik sağlığı için bu dönemlerde kalsiyum takviyesinin kullanılması gerektiği önerilmektedir.

Anahtar Kelimeler

• Östrojen
• Kemik mineral yoğunluğu
• Menstrual döngü.

Kaynakça

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