Defne Uçucu Yağının Fitokimyasal İçeriği ve Farmakolojik Etkilerinin Değerlendirilmesi

Yıl 2024, , 451 - 468, 29.11.2024

Şeyda Güneş , Melek Karaaslan , Burçin Ergene

https://doi.org/10.35193/bseufbd.1285705

Öz

Yaygın olarak defne adıyla bilinen Laurus nobilis L., Lauraceae familyasına ait bir tür olup, Akdeniz ikliminin karakteristik bir bitkisidir. Bitki, ülkemizde kıyı kesimlerinde yayılış göstermektedir ve yapraklarından elde edilen uçucu yağı, halk arasında gıdalarda aroma verici ve baharat olarak kullanılmaktadır. Yapılan çalışmalar sonucunda, terpenik bileşiklerce zengin uçucu yağının, antimikrobiyal, antioksidan, insektisit, akarisidal, antikonvülsan, sitotoksik vb. birçok biyolojik aktiviteye sahip olduğu gösterilmiştir. Uçucu yağın ana bileşiminde yaklaşık 322 bileşik tespit edilmiş olup, ana bileşenlerin 1,8-sineol, α-terpinil asetat olduğu belirlenmiştir. Bu derlemede, L. nobilis yapraklarından elde edilen uçucu yağın geleneksel kullanımı, fitokimyasal içeriği ve biyolojik aktiviteleri vurgulanarak, uçucu yağ hakkında yapılan çalışmaların bilimsel bir sentezinin sunulması amaçlanmaktadır.

Anahtar Kelimeler

Biyolojik Aktivite, Fitokimyasal Çalışma, Defne, Geleneksel Kullanım, Laurus Nobilis

Evaluation of Phytochemical Content and Pharmacological Effects of Laurel Essential Oil

Öz

Laurus nobilis L., commonly known as laurel, is a species belonging to Lauraceae family and a characteristic plant of the Mediterranean climate. The plant is distributed in the coastal areas of our country, and the essential oil obtained from its leaves is used as a flavoring agent and spice in public. The studies conducted on the essential oil, which is rich in terpenic compounds, revealed various biological activities such as antimicrobial, antioxidant, insecticide, acaricidal, anticonvulsant, and cytotoxic activity. Approximately 322 components have been determined in the content of the essential oil and the major components were identified as 1,8-cineole, α-terpinyl acetate. In this review, it is aimed to present a scientific synthesis of the studies on the essential oil by emphasizing the traditional use, phytochemical content and biological activities of the essential oil obtained from the leaves of L. nobilis.

Anahtar Kelimeler

Biological Activity, Laurel, Laurus Nobilis, Phytochemical Study, Traditional Use

Kaynakça

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