Determination of Bacteria by Impedance Measurement Approach Using Proteinoids from Biological Recognition Elements

Yıl 2021, Cilt: 8 Sayı: 2, 668 - 679, 31.12.2021

Asiye Yurttaş

https://doi.org/10.35193/bseufbd.949812

Öz

In today's world, with the developing technology and the increase in water, food and environmental pollution, the health control of these basic needs is quite challenging. There has been a study on the elimination of such deficiencies. For this purpose, a two-stage business plan was created. First; Proteininoids, which are biomolecules that react selectively to target bacteria, were synthesized and characterized. Unlike the biological recognition elements used up to now, proteinoids were used in this study for the first time. In the second stage, proteinoid selectively detects spreading bacteria and cause a change in electrical impedance and physical parameters, thereby providing bioelectric transformation. Diagnostic performance in bacterial stimulation was achieved with electrical characterization methods in the transducer.

Anahtar Kelimeler

Proteinoid, Antibacterial, Biodegradable, Bioelectronic, Impedance

Biyolojik Tanıma Elemanlarından Proteinoidler Kullanılarak Empedans Ölçüm Yaklaşımıyla Bakterilerin Tespiti

Öz

Günümüz dünyasında gelişen teknoloji ile su, gıda ve çevresel kirliliğin artmasıyla bu temel ihtiyaçların sağlık kontrolü oldukça zorlayıcıdır. Bu tür eksiklerin giderilmesi üzerine bir çalışma olmuştur. Bu amaçla iki temel aşamalı bir iş planı oluşturulmuştur. Birincisi; hedef bakteriye seçici tepki veren biyomoleküllerden olan proteinoidler sentezlenip karakterize edilmiştir. Şuana kadar kullanılan biyolojik tanıma elemanlarından ilk defa farklı olarak proteinoidler bu çalışma ile kullanılmıştır. İkinci aşamada ise proteinoidler, yayılım gösteren bakterileri seçici olarak algılayarak elektriksel empedans ile fiziksel parametrelerde değişime neden olarak bioelektrik dönüşümü sağlanmasıdır. Dönüştürücü (transducer) içerisinde elektriksel karakterizasyon yöntemleri ile bakteri uyarımlarında teşhis başarımı elde edilmiştir.

Anahtar Kelimeler

Proteinoid, Antibakteriyel, Biyobozunur, Biyoelektronik, Empedans

Kaynakça

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