Safety of Clinical Biochemistry Laboratories Under Pandemic Conditions: Protective Approaches and Standards
Yıl 2025,
Cilt: 9 Sayı: 3, 164 - 168, 20.12.2025
Gökçe Güven Açık
,
Burcu Gürer Giray
Öz
The COVID-19 pandemic has posed significant occupational risks for healthcare professionals, with clinical laboratory personnel being among the most vulnerable groups. Preventive strategies and treatment algorithms issued by health authorities have undergone continuous revisions as new evidence has emerged. The objective of this review is to systematically summarize the recommended safety measures for biochemistry laboratories during the pandemic, as outlined in international and national guidelines, and to provide a comprehensive framework for optimizing laboratory working conditions under pandemic circumstances.
Kaynakça
-
1. Km H N, Yoon SY, Lm CS, Yoon J. Comparson of three molecular dagnostc assays for SARS CoV2 detecton: Evaluaton of analytcal senstvty and clncal performance. Journal of Clncal Laboratory Analyss. 2022; 36(2): e24242.
-
2. World Health Organzaton (WHO). Dagnostc testng for SARS-CoV-2: nterm gu-dance. 11 September 2020. Avalable at: https://www.who.nt/publcatons//tem/dagnostc-testng-for-sarscov2
-
3. Guan WJ, N ZY, Hu Y, Lang WH, Ou CQ, He JX, et al. Clncal characterstcs of coronavrus dsease 2019 n Chna. N Engl J Med. 2020;382(18):1708–1720.
-
4. Huang C, Wang Y, L X, Ren L, Zhao J, Hu Y, et al. Clncal features of patents nfected wth 2019 novel coronavrus n Wuhan, Chna. Lancet. 2020;395(10223):497–506.
-
5. Zhou F, Yu T, Du R, Fan G, Lu Y, Lu Z, et al. Clncal course and rsk factors for mortal
ty of adult npatents wth COVID-19 n Wuhan, Chna: a retrospectve cohort study.
Lancet. 2020;395(10229):1054–1062.
-
6. CDC. People wth Certan Medcal Condtons. Centers for Dsease Control and Prevent
on. https://www.cdc.gov/coronavrus/2019-ncov/need-extra-precautons/people-wth-
medcal-condtons.html.
-
7. Health and Safety Executve (HSE), UK. Advsory Commttee on Dangerous Pathogens
(ACDP) classfcaton of bologcal agents. Updated classfcaton for SARS-CoV-2, 2020.
-
8. World Health Organzaton (WHO). WHO Drector-General’s openng remarks at the
meda brefng on COVID-19 – 11 March 2020.
-
9. T.C. Saglık Bakanlıgı. COVID-19 Bilglendrme Platformu. https://covd19.saglk.gov.tr
-
10. CDC. Bosafety n Mcrobologcal and Bomedcal Laboratores (BMBL), 6th Edton.
Centers for Dsease Control and Preventon, 2020, Belgan Bosafety Server. SARS-CoV-2
classfcaton and bosafety measures n Belgum. Belgan Bosafety Network, 2020.
-
11. T.C. Saglık Bakanlıgı Saglık Hzmetler Genel Müdürlügü Tetkk ve Teshs Hzmetler Da-
re Baskanlıgı COVID-19 (SARS-CoV-2 enfeksyonu) laboratuvar byogüvenlk rehber.
Avalable at: https://dosyamerkez.saglk.gov.tr/Eklent/37137,covd-19-sars-cov-2-enfeks
yonu-laboratuvarbyoguvenlk-rehberpdf.pdf.
-
12. World Health Organzaton (WHO). Laboratory bosafety gudance related to SARSCoV-
2 (COVID-19): Interm gudance, 11 March 2024. Avalable at: https://www.who.
nt/publcatons//tem/who-whe-epp-2024.3
-
13. Wyor HD, Coburn JC, Segel KL. Impact of clncan personal protectve equpment on
medcal devce use durng publc health emergency: A revew. Dsaster Medcne and
Publc Health Preparedness.2020: 14(2); 273-283.
-
14. Parush A, Wacht O, Gomes R, Frenkel A. Human factor consderatons n usng personal
protectve equpment n the COVID-19 pandemc context: bnatonal survey study.
Journal of medcal Internet research. 2020: 22(6);e19947.
-
15. Song M, L ZL, Zhou YJ, Tan G, Ye T, Zeng ZR, Lu JB. Gastrontestnal nvolvement of
COVID-19 and potental faecal transmsson of SARS-CoV-2. Journal of Zhejang Un-
versty-SCIENCE B. 2020; 21(9): 749-751.
-
16. Godoy LRG, Jones AE, Anderson TN, Fsher CL, Seeley KM, Beeson E A, Sullvan PD.
Facal protecton for healthcare workers durng pandemcs: a scopng revew. BMJ global
health. 2020; 5(5): e002553.
-
17. T.C. Saglık Bakanlıgı, saglık kurumlarında enfeksyon kontrol önlemler, kssel koruyucu
ekpman kullanımı. Avalable at: https://covd19blg.saglk.gov.tr/tr/.
Pandemi Koşullarında Tıbbi Biyokimya Laboratuvarlarının Güvenliği: Koruyucu Yaklaşımlar ve Standartlar
Yıl 2025,
Cilt: 9 Sayı: 3, 164 - 168, 20.12.2025
Gökçe Güven Açık
,
Burcu Gürer Giray
Öz
COVID-19 hastalığı, sağlık çalışanları ve özellikle klinik laboratuvar çalışanları için oldukça riskli ve kaotik bir süreç oluşturdu. Yetkililer tarafından açıklanan önleme tedbirleri ve tedavi algoritmaları her geçen gün değişmektedir. Bu derlemenin amacı, rehberler doğrultusunda pandemi sırasında biyokimya laboratuvarında gerçekleştirilmesi gereken önlemleri bütün halinde sıralayarak laboratuvar çalışma koşullarının düzenlenmesine katkı sağlamaktır.
Kaynakça
-
1. Km H N, Yoon SY, Lm CS, Yoon J. Comparson of three molecular dagnostc assays for SARS CoV2 detecton: Evaluaton of analytcal senstvty and clncal performance. Journal of Clncal Laboratory Analyss. 2022; 36(2): e24242.
-
2. World Health Organzaton (WHO). Dagnostc testng for SARS-CoV-2: nterm gu-dance. 11 September 2020. Avalable at: https://www.who.nt/publcatons//tem/dagnostc-testng-for-sarscov2
-
3. Guan WJ, N ZY, Hu Y, Lang WH, Ou CQ, He JX, et al. Clncal characterstcs of coronavrus dsease 2019 n Chna. N Engl J Med. 2020;382(18):1708–1720.
-
4. Huang C, Wang Y, L X, Ren L, Zhao J, Hu Y, et al. Clncal features of patents nfected wth 2019 novel coronavrus n Wuhan, Chna. Lancet. 2020;395(10223):497–506.
-
5. Zhou F, Yu T, Du R, Fan G, Lu Y, Lu Z, et al. Clncal course and rsk factors for mortal
ty of adult npatents wth COVID-19 n Wuhan, Chna: a retrospectve cohort study.
Lancet. 2020;395(10229):1054–1062.
-
6. CDC. People wth Certan Medcal Condtons. Centers for Dsease Control and Prevent
on. https://www.cdc.gov/coronavrus/2019-ncov/need-extra-precautons/people-wth-
medcal-condtons.html.
-
7. Health and Safety Executve (HSE), UK. Advsory Commttee on Dangerous Pathogens
(ACDP) classfcaton of bologcal agents. Updated classfcaton for SARS-CoV-2, 2020.
-
8. World Health Organzaton (WHO). WHO Drector-General’s openng remarks at the
meda brefng on COVID-19 – 11 March 2020.
-
9. T.C. Saglık Bakanlıgı. COVID-19 Bilglendrme Platformu. https://covd19.saglk.gov.tr
-
10. CDC. Bosafety n Mcrobologcal and Bomedcal Laboratores (BMBL), 6th Edton.
Centers for Dsease Control and Preventon, 2020, Belgan Bosafety Server. SARS-CoV-2
classfcaton and bosafety measures n Belgum. Belgan Bosafety Network, 2020.
-
11. T.C. Saglık Bakanlıgı Saglık Hzmetler Genel Müdürlügü Tetkk ve Teshs Hzmetler Da-
re Baskanlıgı COVID-19 (SARS-CoV-2 enfeksyonu) laboratuvar byogüvenlk rehber.
Avalable at: https://dosyamerkez.saglk.gov.tr/Eklent/37137,covd-19-sars-cov-2-enfeks
yonu-laboratuvarbyoguvenlk-rehberpdf.pdf.
-
12. World Health Organzaton (WHO). Laboratory bosafety gudance related to SARSCoV-
2 (COVID-19): Interm gudance, 11 March 2024. Avalable at: https://www.who.
nt/publcatons//tem/who-whe-epp-2024.3
-
13. Wyor HD, Coburn JC, Segel KL. Impact of clncan personal protectve equpment on
medcal devce use durng publc health emergency: A revew. Dsaster Medcne and
Publc Health Preparedness.2020: 14(2); 273-283.
-
14. Parush A, Wacht O, Gomes R, Frenkel A. Human factor consderatons n usng personal
protectve equpment n the COVID-19 pandemc context: bnatonal survey study.
Journal of medcal Internet research. 2020: 22(6);e19947.
-
15. Song M, L ZL, Zhou YJ, Tan G, Ye T, Zeng ZR, Lu JB. Gastrontestnal nvolvement of
COVID-19 and potental faecal transmsson of SARS-CoV-2. Journal of Zhejang Un-
versty-SCIENCE B. 2020; 21(9): 749-751.
-
16. Godoy LRG, Jones AE, Anderson TN, Fsher CL, Seeley KM, Beeson E A, Sullvan PD.
Facal protecton for healthcare workers durng pandemcs: a scopng revew. BMJ global
health. 2020; 5(5): e002553.
-
17. T.C. Saglık Bakanlıgı, saglık kurumlarında enfeksyon kontrol önlemler, kssel koruyucu
ekpman kullanımı. Avalable at: https://covd19blg.saglk.gov.tr/tr/.