Thorax Computed Tomography Findings in COVID-19 Infection

Öz

The 2019 new coronavirus disease (COVID-19) is an important public health issue that spreads worldwide. Though the gold standard real-time reverse transcription polymerase chain reaction (RT-PCR) test is used in diagnosis, thorax computed tomography (CT) is an important guide especially in patients with clinical symptoms and the test is negative. The purpose of this review is to summarize the findings found in thorax CT, which is increasingly used in the diagnosis of COVID-19.

Anahtar Kelimeler

• : COVID-19,computed tomography,radiology

COVID-19 Enfeksiyonunda Toraks Bilgisayarlı Tomografi Bulguları

Öz

2019 yeni koronavirüs hastalığı (COVID-19), tüm dünyaya yayılan önemli bir halk sağlığı sorunudur. Tanıda altın standart real-time reverse transcription polymerase chain reaction (RT-PCR) testi olsa da, özellikle klinik semptomu olup testin negatif geldiği hastalarda toraks bilgisayarlı tomografi (BT) önemli bir yol göstericidir. Bu derlemenin amacı, COVID-19’un tanısında giderek daha fazla kullanılan toraks BT’de saptanan bulguları özetlemektir.

Anahtar Kelimeler

• COVID-19,bilgisayarlı tomografi,radyoloji

Kaynakça

1. 1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020; 382: 727-733.
2. 2. COVID C, Team R. Severe outcomes among patients with coronavirus disease 2019 (COVID-19)—United States, February 12–March 16, 2020. MMWR Morb Mortal Wkly Rep. 2020; 69: 343-346.
3. 3. Akcay MS. Radiological Approaches to Covid-19 Pneumonia. Turk J Med Sci. 2020.
4. 4. Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing. Radiology. 2020: 200343.
5. 5. Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P, Ji W. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology. 2020: 200432.
6. 6. Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, Tao Q, Sun Z, Xia L. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020: 200642.
7. 7. Erturk SM. CT of Coronavirus Disease (COVID-19) Pneumonia: A Reference Standard Is Needed. AJR Am J Roentgenol. 2020: W1.
8. 8. Xu X, Chen P, Wang J, Feng J, Zhou H, Li X, Zhong W, Hao P. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. Sci China Life Sci. 2020; 63: 457-460.

9. 9. Kanne JP, Little BP, Chung JH, Elicker BM, Ketai LH. Essentials for Radiologists on COVID-19: An Update-Radiology Scientific Expert Panel. Radiology. 2020: 200527.
10. 10. Nair A, Rodrigues JCL, Hare S, Edey A, Devaraj A, Jacob J, Johnstone A, McStay R, Denton E, Robinson G. A British Society of Thoracic Imaging statement: considerations in designing local imaging diagnostic algorithms for the COVID-19 pandemic. Clin Radiol. 2020; 75: 329-334.
11. 11. Yang R, Li X, Liu H, Zhen Y, Zhang X, Xiong Q, Luo Y, Gao C, Zeng W. Chest CT Severity Score: An Imaging Tool for Assessing Severe COVID-19. Radiology: Cardiothoracic Imaging. 2020; 2: e200047.
12. 12. Özkan R. Yaygın Akciğer Hastalıklarında Radyografi. Trd Sem. 2017; 5: 82-97.
13. 13. Ye Z, Zhang Y, Wang Y, Huang Z, Song B. Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review. Eur Radiol. 2020.
14. 14. Salehi S, Abedi A, Balakrishnan S, Gholamrezanezhad A. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients. AJR Am J Roentgenol. 2020: 1-7.
15. 15. Caruso D, Zerunian M, Polici M, Pucciarelli F, Polidori T, Rucci C, Guido G, Bracci B, de Dominicis C, Laghi A. Chest CT Features of COVID-19 in Rome, Italy. Radiology. 2020: 201237.
16. 16. Chung M, Bernheim A, Mei X, Zhang N, Huang M, Zeng X, Cui J, Xu W, Yang Y, Fayad ZA, Jacobi A, Li K, Li S, Shan H. CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV). Radiology. 2020; 295: 202-207.
17. 17. Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, Liu S, Zhao P, Liu H, Zhu L, Tai Y, Bai C, Gao T, Song J, Xia P, Dong J, Zhao J, Wang FS. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020; 8: 420-422.
18. 18. Song F, Shi N, Shan F, Zhang Z, Shen J, Lu H, Ling Y, Jiang Y, Shi Y. Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia. Radiology. 2020; 295: 210-217.
19. 19. Wu J, Wu X, Zeng W, Guo D, Fang Z, Chen L, Huang H, Li C. Chest CT Findings in Patients With Coronavirus Disease 2019 and Its Relationship With Clinical Features. Invest Radiol. 2020; 55: 257-261.
20. 20. Shi H, Han X, Jiang N, Cao Y, Alwalid O, Gu J, Fan Y, Zheng C. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis. 2020; 20: 425-434.
21. 21. Hansell DM, Bankier AA, MacMahon H, McLoud TC, Muller NL, Remy J. Fleischner Society: glossary of terms for thoracic imaging. Radiology. 2008; 246: 697-722.
22. 22. Wong KT, Antonio GE, Hui DS, Lee N, Yuen EH, Wu A, Leung CB, Rainer TH, Cameron P, Chung SS, Sung JJ, Ahuja AT. Thin-section CT of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the disease. Radiology. 2003; 228: 395-400.
23. 23. Pan F, Ye T, Sun P, Gui S, Liang B, Li L, Zheng D, Wang J, Hesketh RL, Yang L, Zheng C. Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia. Radiology. 2020: 200370.
24. 24. Li K, Wu J, Wu F, Guo D, Chen L, Fang Z, Li C. The Clinical and Chest CT Features Associated with Severe and Critical COVID-19 Pneumonia. Invest Radiol. 2020.
25. 25. Xu R, Du M, Li L, Zhen Z, Wang H, Hu X. CT imaging of one extended family cluster of corona virus disease 2019 (COVID-19) including adolescent patients and "silent infection". Quant Imaging Med Surg. 2020; 10: 800-804.
26. 26. Pinto PS. The CT Halo Sign. Radiology. 2004; 230: 109-10.
27. 27. Taydas O, Erarslan Y, Atceken Z, Ariyurek OM. Granulomatoz polianjitte (Wegener granulomatozu) toraks BT bulguları. Türk Radyoloji Derg. 2017; 36: 86-88.
28. 28. Kim SJ, Lee KS, Ryu YH, Yoon YC, Choe KO, Kim TS, Sung KJ. Reversed halo sign on high-resolution CT of cryptogenic organizing pneumonia: diagnostic implications. AJR Am J Roentgenol. 2003; 180: 1251-4.