Coffee Active Ingredient Loaded Biopolymer Nanoparticles: Synthesis and Characterization

Yıl 2024, , 72 - 81, 28.06.2024

Özge Vardar Ayça Mehmetoğlu Al Yeliz Yıldırım

https://doi.org/10.18466/cbayarfbe.1448091

Öz

Cafestol (CFS) is present in unfiltered coffee types and exhibits antidiabetic, anti-inflammatory and anticarcinogenic properties. The ionic gelation method was used to synthesise CFS-loaded chitosan (CS), and alginate (ALG) nanoparticles with high loading efficiency. The characterization, thermal properties and surface morphology of CFS-loaded biopolymer nanoparticles were carried out by FTIR, TGA and SEM, respectively. The encapsulation efficiency of the synthesised CFS-loaded biopolymer nanoparticles was found to be as 53% (CFS-loaded ALGNPs) and 92% (CFS-loaded CSNPs) by high-pressure liquid chromatography. The particle sizes determined using Malvern Zeta Sizer Ultra were 97 ± 4.04 (CFS-loaded CSNPs) and 81 ± 6.51 (CFS-loaded ALGNPs).

Anahtar Kelimeler

Alginate, Cafestol, Chitosan, Drug Delivery Systems, Nanoparticle

Destekleyen Kurum

BAP Project No. 21692

Proje Numarası

BAP Project No. 21692

Teşekkür

Acknowledgements This research is supported by grants from the Ege University Scientific Research Coordination Office (BAP Project No. 21692).

Kaynakça

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