Coffee Active Ingredient Loaded Biopolymer Nanoparticles: Synthesis and Characterization

Öz

Cafestol (CFS) is present in unfiltered coffee types and exhibits antidiabetic, anti-inflammatory and anticarcinogenic properties. The ionic gelation method was used to synthesise CFS-loaded chitosan (CS), and alginate (ALG) nanoparticles with high loading efficiency. The characterization, thermal properties and surface morphology of CFS-loaded biopolymer nanoparticles were carried out by FTIR, TGA and SEM, respectively. The encapsulation efficiency of the synthesised CFS-loaded biopolymer nanoparticles was found to be as 53% (CFS-loaded ALGNPs) and 92% (CFS-loaded CSNPs) by high-pressure liquid chromatography. The particle sizes determined using Malvern Zeta Sizer Ultra were 97 ± 4.04 (CFS-loaded CSNPs) and 81 ± 6.51 (CFS-loaded ALGNPs).

Anahtar Kelimeler

• Alginate
• Cafestol
• Chitosan
• Drug Delivery Systems
• Nanoparticle

Kaynakça

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