Yıl 2019, Cilt 15 , Sayı 3, Sayfalar 271 - 277 2019-09-30

A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis

Fariba Ghaderinezhad [1] , Savas Tasoglu [2]


The electrochemical method offers a sensitive, portable, and cost-effective method for detecting a range of analytes and has the capacity to be miniaturized. However, according to the World Health Organization, there is a need for point-of-care devices that meet the criteria for medical diagnostics in remote and resource-limited regions, as set forth by the World Health Organization. In this context, we developed a low-cost and high-throughput method for fabricating paper-based devices for electrochemical assays using a desktop pen plotter. In this study, we used a permanent marker to plot hydrophobic barriers and a liquid dispenser to pattern three electrodes (working, counter, and reference electrodes) with carbon paste on a paper substrate. To test the performance of the fabricated electrochemical devices, chronoamperometric and cyclic voltammetric analyses of potassium ferricyanide was conducted. Further, to demonstrate of the possible biomedical diagnostic applications, a quantitative glucose assay was performed. Here, we presented a low-cost electrochemical device fabrication method convenient for large-scale fabrication and widespread implementation of paper-based technologies in developing countries and resource-limited settings.

pen plotter, paper-based assays, electrochemical, glucose assay, high-throughput, biosensor
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Birincil Dil en
Konular Mühendislik
Yayımlanma Tarihi 30-09-2019
Bölüm Makaleler
Yazarlar

Yazar: Fariba Ghaderinezhad

Orcid: 0000-0003-4604-217X
Yazar: Savas Tasoglu (Sorumlu Yazar)
Kurum: University of Connecticut
Ülke: United States


Tarihler

Yayımlanma Tarihi : 30 Eylül 2019

Bibtex @araştırma makalesi { cbayarfbe542120, journal = {Celal Bayar University Journal of Science}, issn = {1305-130X}, eissn = {1305-1385}, address = {}, publisher = {Celal Bayar Üniversitesi}, year = {2019}, volume = {15}, pages = {271 - 277}, doi = {10.18466/cbayarfbe.542120}, title = {A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis}, key = {cite}, author = {Ghaderinezhad, Fariba and Tasoglu, Savas} }
APA Ghaderinezhad, F , Tasoglu, S . (2019). A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis. Celal Bayar University Journal of Science , 15 (3) , 271-277 . DOI: 10.18466/cbayarfbe.542120
MLA Ghaderinezhad, F , Tasoglu, S . "A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis". Celal Bayar University Journal of Science 15 (2019 ): 271-277 <https://dergipark.org.tr/tr/pub/cbayarfbe/issue/48815/542120>
Chicago Ghaderinezhad, F , Tasoglu, S . "A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis". Celal Bayar University Journal of Science 15 (2019 ): 271-277
RIS TY - JOUR T1 - A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis AU - Fariba Ghaderinezhad , Savas Tasoglu Y1 - 2019 PY - 2019 N1 - doi: 10.18466/cbayarfbe.542120 DO - 10.18466/cbayarfbe.542120 T2 - Celal Bayar University Journal of Science JF - Journal JO - JOR SP - 271 EP - 277 VL - 15 IS - 3 SN - 1305-130X-1305-1385 M3 - doi: 10.18466/cbayarfbe.542120 UR - https://doi.org/10.18466/cbayarfbe.542120 Y2 - 2019 ER -
EndNote %0 Celal Bayar Üniversitesi Fen Bilimleri Dergisi A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis %A Fariba Ghaderinezhad , Savas Tasoglu %T A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis %D 2019 %J Celal Bayar University Journal of Science %P 1305-130X-1305-1385 %V 15 %N 3 %R doi: 10.18466/cbayarfbe.542120 %U 10.18466/cbayarfbe.542120
ISNAD Ghaderinezhad, Fariba , Tasoglu, Savas . "A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis". Celal Bayar University Journal of Science 15 / 3 (Eylül 2019): 271-277 . https://doi.org/10.18466/cbayarfbe.542120
AMA Ghaderinezhad F , Tasoglu S . A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis. Celal Bayar Univ J Sci. 2019; 15(3): 271-277.
Vancouver Ghaderinezhad F , Tasoglu S . A Hybrid Approach for Large-scale Fabrication of Paper-based Electrochemical Assays for Biomedical Diagnosis. Celal Bayar University Journal of Science. 2019; 15(3): 277-271.