Araştırma Makalesi
BibTex RIS Kaynak Göster

Resveratrol Desteği Akut Yüzme Egzersizi Yaptırılan Sıçanların Bazı Dokularında Element Metabolizmasıyla İlişkilidir

Yıl 2023, Cilt: 18 Sayı: 2, 399 - 410, 31.12.2023
https://doi.org/10.33459/cbubesbd.1261924

Öz

Bu çalışmanın amacı, akut yüzme egzersizi yaptırılan sıçanlarda resveratrol uygulamasının bazı dokulardaki element metabolizmasını nasıl etkilediğini araştırmaktır. Wistar cinsi 28 adet erişkin erkek sıçan kullanılan araştırmada hayvanlar eşit sayıda 4 gruba ayrıldı. Grup 1, Kontrol; Grup 2, Yüzme: Standart diyetle beslenen ve 30 dakika akut yüzme egzersizi yaptırılan grup. Grup 3, Resveratrol: Dört hafta boyunca 10 mg/kg resveratrol desteği alan grup. Grup 4, Resveratrol + Yüzme: Dört hafta boyunca 10 mg/kg resveratrol desteği alan ve 30 dakika akut yüzme egzersizi yaptırılan grup. Dört haftalık diyet uygulamalarının bitiminde grup 2 ve grup 4 hayvanlarına 30 dakika akut yüzme egzersizi yaptırıldı. Yüzme uygulamalarından hemen sonra hayvanlar sakrifiye edilerek testis, böbrek, kalp ve karaciğer doku örnekleri alındı. Alınan doku örneklerinde element analizleri atomik emisyon yöntemiyle tayin edildi. Testis dokusundaki ölçümü yapılan elementler egzersiz ve resveratrol uygulamalarından etkilenmedi. Hem resveratrol uygulaması hem de akut yüzme egzersizi böbrek dokusunda çinko, demir, magnezyum, selenyum, molibden, kalp dokusunda demir, kalsiyum ve karaciğer dokusunda ise çinko, demir, molibden seviyelerinde değişikle sonuçlandı (p<0.05). Resveratrol uygulamasının hem egzersizde, hem de egzersizden bağımsız olarak sıçanların bazı dokularında element metabolizmasında değişikliklere yol açtığını ortaya koyan çalışmamızın bulguları med-line taramalardan yola çıkarak ilk ve orijinal bulgu olarak takdim edilebilir.

Proje Numarası

SUBAPK; project no. 1420132013

Kaynakça

  • Baltaci, S.B., Mogulkoc, R., & Baltaci, A.K. (2016). Resveratrol and exercise. Biomedical Reports, 5(5),525-530. https://doi.org/10.3892/br.2016.777
  • Bicer, M., Akil, M., Baltaci, A.K., Mogulkoc, R., Sivrikaya, A., & Akkus, H. (2015). Effect of melatonin on element distribution in the liver tissue of diabetic rats subjected to forced exercise. Bratislavské Lekárske Listy, 116(2), 119-123. https://doi.org/10.4149/bll_2015_023
  • Bobrowska-Korczak, B., Skrajnowska, D., & Tokarz, A. (2012). The effect of dietary zinc--and polyphenols intake on DMBA-induced mammary tumorigenesis in rats. Journal of Biomedical Science, 9(1), 43. https://doi.org/10.1186/1423-0127-19-43
  • Córdova, A., & Navas, F.J. (1998). Effect of training on zinc metabolism: Changes in serum and sweat zinc concentrations in sportsmen.Annals of Nutrition & Metabolism, 42(5), 274-282. https://doi.org/10.1159/000012744
  • Cordova, A. (1994). Zinc content in selected tissues in streptozotocin-diabetic rats after maximal exercise. Biological Trace Element Research, 42(3), 209-216. https://doi.org/10.1007/BF02911518
  • Fischer, P.W., Giroux, A., & L'Abbé, M.R. (1984) Effect of zinc supplementation on copper status in adult man. American Journal of Clinical Nutrition, 40(4),743-746. https://doi.org/10.1093/ajcn/40.4.743
  • Ghio, A.J., Soukup, J.M., Ghio, C., Gordon, C.J., Richards, J.E., Schladweiler, M.C., Snow, S.J., & Kodavanti, U.P. (2021) Iron and zinc homeostases in female rats with physically active and sedentary lifestyles. Biometals, 34(1), 97-105. https://doi.org/10.1007/s10534-020-00266-w
  • Heffernan, S.M., Horner, K., De Vito, G., & Conway, G.E. (2019) The role of mineral and trace element supplementation in exercise and athletic performance: A Systematic review. Nutrients,11(3), 696. https://doi.org/10.3390/nu11030696
  • Jo, E., Bartosh, R., Auslander, A.T., Directo, D., Osmond, A., &Wong, M.W. (2019). Post Exercise recovery following 30-day supplementation of trans-resveratrol and polyphenol-enriched extracts. Sports (Basel), 7(10), 226. https://doi.org/10.3390/sports7100226
  • Kaptanoğlu, B., Turgut, G., Genç, O., Enli, Y., Karabulut, I., Zencir, M., & Turgut, S. (2003). Effects of acute exercise on the levels of iron, magnesium, and uric acid in liver and spleen tissues. Biological Trace Element Research, 91(2), 173-178. https://doi.org/10.1385/BTER:91:2:173
  • Kaya, O., Gokdemir, K., Kilic, M., & Baltaci, A.K. (2006). Melatonin supplementation to rats subjected to acute swimming exercise: Its effect on plasma lactate levels and relation with zinc. Neuro Endocrinology Letters, 27(1-2), 263-266.
  • Kharb, S., & Singh, V. (2000). Magnesium deficiency potentiates free radical production associated with myocardial infarction. The Journal of the Association of Physicians of India, 48(5), 484-485. Retrieved from: http://www.japi.org/
  • Kuru, O., Sentürk, U.K., Gündüz, F., Aktekin, B., & Aktekin, M.R. (2003). Effect of long-term swimming exercise on zinc, magnesium, and copper distribution in aged rats. Biological Trace Element Research, 93(1-3), 105-112. https://doi.org/10.1385/BTER:93:1-3:105
  • Liu, Y.Q., Duan, X.L., Chang, Y.Z., Wang, H.T., & Qian, Z.M. (2006). Molecular analysis of increased iron status in moderately exercised rats. Molecular and Cellular Biochemistry, 282(1-2), 117-123. https://doi.org/10.1007/s11010006-1522-4
  • Lukaski, H.C. (1989). Effects of exercise training on human copper and zinc nutriture. Advances in Experimental Medicine and Biology, 258, 163-170. https://doi.org/10.1007/978-1-4613-0537-8_14
  • Maughan, R.J. (1999). Role of micronutrients in sport and physical activity. British Medical Bulletin, 55(3), 683-690. https://doi.org/10.1258/0007142991902556
  • McDonald, R., Hegenauer, J., & Saltman, P. (1986) Age-related differences in the bone mineralization pattern of rats following exercise. Journal of Gerontology,41(4), 445-452. https://doi.org/10.1093/geronj/41.4.445
  • Mercken, E.M., Carboneau, B.A., Krzysik-Walker, S.M., & de Cabo, R. (2012). Of mice and men: the benefits of caloric restriction, exercise, and mimetics. Aging Research Reviews, 11(3), 390-398. https://doi.org/10.1016/j.arr.2011.11.005
  • Navas, F.J., &Córdova, A. (2000). Iron distribution in different tissues in rats following exercise. Biological Trace Element Research, 73(3), 259-268. https://doi.org/10.1385/BTER:73:3:259
  • NIST Standard reference materials catalog. (1996). NIST Special Publication 260, Standards Reference Material Programme, U.S. Department of Commerce, Gaithersburg, MD 20899-0001, USA
  • Ozturk, A., Baltaci, A.K., Mogulkoc, R., Oztekin, E., Sivrikaya, A., Kurtoglu, E., & Kul, A. (2003). Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissues of rats performing swimming exercise. Biological Trace Element Research,94(2), 157-166. https://doi.org/10.1385/BTER:94:2:157
  • Patlar, S., Gulnar, U., Baltaci, A.K., & Mogulkoc, R. (2014) Effect of nocturnal exhaustion exercise on the metabolism of selected elements. Archives of Biological Sciences, 66(4),1595-1601. https://doi.org/10.2298/ABS1404595P
  • Pingitore, A., Lima, G.P., Mastorci, F., Quinones, A., Iervasi, G., & Vassalle, C. (2015). Exercise and oxidative stress: potential effects of antioxidant dietary strategies in sports. Nutrition, 31(7-8), 916-922. https://doi.org/10.1016/j.nut.2015.02.005
  • Schrauwen, P., & Timmers, S. (2014). Can resveratrol help to maintain metabolic health? The Proceedings of the Nutrition Society, 73(2), 271-277. https://doi.org/10.1017/S0029665113003856
  • Sharman, J.E., La Gerche, A., & Coombes, J.S. (2015). Exercise and cardiovascular risk in patients with hypertension. American Journal of Hypertension, 28(2), 147-158. https://doi.org/10.1093/ajh/hpu191
  • Sivrikaya, A., Akil, M., Bicer, M., Kilic, M., Baltaci, A.K., & Mogulkoc, R. (2013). The effect of selenium supplementation on elements distribution in liver of rats subject to strenuous swimming. Bratislavské Lekárske Listy,114(1), 12-14. https://doi.org/10.4149/bll_2013_003
  • Sivrikaya, A., Bicer, M., Akil, M., Baltaci, A.K., & Mogulkoc, R. (2012). Effects of zinc supplementation on the element distribution in kidney tissue of diabetic rats subjected to acute swimming. Biological Trace Element Research,147(1-3), 195-199. https://doi.org/10.1007/s12011-011-9284-6
  • Skrajnowska, D., Bobrowska-Korczak, B., Tokarz, A., Bialek, S., Jezierska, E., & Makowska, J. (2013). Copper and resveratrol attenuates serum catalase, glutathione peroxidase, and element values in rats with DMBA-induced mammary carcinogenesis. Biological Trace Element Research,156(1-3), 271-278. https://doi.org/10.1007/s12011013-9854-x
  • Wells, I.C. (2008). Evidence that the etiology of the syndrome containing type 2 diabetes mellitus results from abnormal magnesium metabolism. Canadian Journal of Physiology and Pharmacology, 86(1-2), 16-24. https://doi.org/10.1139/y07-122
  • Zhao, L., Wang, Y., Wang, Z., Xu, Z., Zhang Q., & Yin, M. (2015) Effects of dietary resveratrol on excess-iron-induced bone loss via antioxidative character. The Journal of Nutritional Biochemistry, 26(11), 1174-1182. https://doi.org/10.1016/j.jnutbio.2015.05.009

Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats

Yıl 2023, Cilt: 18 Sayı: 2, 399 - 410, 31.12.2023
https://doi.org/10.33459/cbubesbd.1261924

Öz

The aim of this study was to investigate how resveratrol administration affects element metabolism in some tissues in rats undergoing acute swimming exercise. In the study, 28 adult male Wistar rats were used and the animals were divided into 4 groups in equal numbers. Group 1, Control; Group 2, Swimming: The group fed a standard diet and had 30 minutes of acute swimming exercise. Group 3, Resveratrol: The group receiving 10 mg/kg resveratrol supplement for four weeks. Group 4, Resveratrol + Swimming: The group that received 10 mg/kg resveratrol supplement for four weeks and also had 30 minutes of acute swimming exercise. At the end of the four-weeks diet, group 2 and group 4 animals were given 30 minutes of acute swimming exercise. Animals were sacrificed immediately after swimming practices, and testis, kidney, heart and liver tissue samples were taken. Elemental analyzes in tissue samples were determined by atomic emission method. Elements measured in testicular tissue were not affected by exercise and resveratrol applications. Both resveratrol administration and acute swimming exercise resulted in changes in zinc, iron, magnesium, selenium, molybdenum levels in kidney tissue, iron and calcium levels in heart tissue, and zinc, iron and molybdenum levels in liver tissue (p<0.05). The results of study, which revealed that resveratrol administration caused changes in element metabolism in some tissues of rats both during and independently of exercise, can be presented as the first and original finding based on med-line scans.

Destekleyen Kurum

Scientific Research Projects Coordinatorship of Selcuk University

Proje Numarası

SUBAPK; project no. 1420132013

Kaynakça

  • Baltaci, S.B., Mogulkoc, R., & Baltaci, A.K. (2016). Resveratrol and exercise. Biomedical Reports, 5(5),525-530. https://doi.org/10.3892/br.2016.777
  • Bicer, M., Akil, M., Baltaci, A.K., Mogulkoc, R., Sivrikaya, A., & Akkus, H. (2015). Effect of melatonin on element distribution in the liver tissue of diabetic rats subjected to forced exercise. Bratislavské Lekárske Listy, 116(2), 119-123. https://doi.org/10.4149/bll_2015_023
  • Bobrowska-Korczak, B., Skrajnowska, D., & Tokarz, A. (2012). The effect of dietary zinc--and polyphenols intake on DMBA-induced mammary tumorigenesis in rats. Journal of Biomedical Science, 9(1), 43. https://doi.org/10.1186/1423-0127-19-43
  • Córdova, A., & Navas, F.J. (1998). Effect of training on zinc metabolism: Changes in serum and sweat zinc concentrations in sportsmen.Annals of Nutrition & Metabolism, 42(5), 274-282. https://doi.org/10.1159/000012744
  • Cordova, A. (1994). Zinc content in selected tissues in streptozotocin-diabetic rats after maximal exercise. Biological Trace Element Research, 42(3), 209-216. https://doi.org/10.1007/BF02911518
  • Fischer, P.W., Giroux, A., & L'Abbé, M.R. (1984) Effect of zinc supplementation on copper status in adult man. American Journal of Clinical Nutrition, 40(4),743-746. https://doi.org/10.1093/ajcn/40.4.743
  • Ghio, A.J., Soukup, J.M., Ghio, C., Gordon, C.J., Richards, J.E., Schladweiler, M.C., Snow, S.J., & Kodavanti, U.P. (2021) Iron and zinc homeostases in female rats with physically active and sedentary lifestyles. Biometals, 34(1), 97-105. https://doi.org/10.1007/s10534-020-00266-w
  • Heffernan, S.M., Horner, K., De Vito, G., & Conway, G.E. (2019) The role of mineral and trace element supplementation in exercise and athletic performance: A Systematic review. Nutrients,11(3), 696. https://doi.org/10.3390/nu11030696
  • Jo, E., Bartosh, R., Auslander, A.T., Directo, D., Osmond, A., &Wong, M.W. (2019). Post Exercise recovery following 30-day supplementation of trans-resveratrol and polyphenol-enriched extracts. Sports (Basel), 7(10), 226. https://doi.org/10.3390/sports7100226
  • Kaptanoğlu, B., Turgut, G., Genç, O., Enli, Y., Karabulut, I., Zencir, M., & Turgut, S. (2003). Effects of acute exercise on the levels of iron, magnesium, and uric acid in liver and spleen tissues. Biological Trace Element Research, 91(2), 173-178. https://doi.org/10.1385/BTER:91:2:173
  • Kaya, O., Gokdemir, K., Kilic, M., & Baltaci, A.K. (2006). Melatonin supplementation to rats subjected to acute swimming exercise: Its effect on plasma lactate levels and relation with zinc. Neuro Endocrinology Letters, 27(1-2), 263-266.
  • Kharb, S., & Singh, V. (2000). Magnesium deficiency potentiates free radical production associated with myocardial infarction. The Journal of the Association of Physicians of India, 48(5), 484-485. Retrieved from: http://www.japi.org/
  • Kuru, O., Sentürk, U.K., Gündüz, F., Aktekin, B., & Aktekin, M.R. (2003). Effect of long-term swimming exercise on zinc, magnesium, and copper distribution in aged rats. Biological Trace Element Research, 93(1-3), 105-112. https://doi.org/10.1385/BTER:93:1-3:105
  • Liu, Y.Q., Duan, X.L., Chang, Y.Z., Wang, H.T., & Qian, Z.M. (2006). Molecular analysis of increased iron status in moderately exercised rats. Molecular and Cellular Biochemistry, 282(1-2), 117-123. https://doi.org/10.1007/s11010006-1522-4
  • Lukaski, H.C. (1989). Effects of exercise training on human copper and zinc nutriture. Advances in Experimental Medicine and Biology, 258, 163-170. https://doi.org/10.1007/978-1-4613-0537-8_14
  • Maughan, R.J. (1999). Role of micronutrients in sport and physical activity. British Medical Bulletin, 55(3), 683-690. https://doi.org/10.1258/0007142991902556
  • McDonald, R., Hegenauer, J., & Saltman, P. (1986) Age-related differences in the bone mineralization pattern of rats following exercise. Journal of Gerontology,41(4), 445-452. https://doi.org/10.1093/geronj/41.4.445
  • Mercken, E.M., Carboneau, B.A., Krzysik-Walker, S.M., & de Cabo, R. (2012). Of mice and men: the benefits of caloric restriction, exercise, and mimetics. Aging Research Reviews, 11(3), 390-398. https://doi.org/10.1016/j.arr.2011.11.005
  • Navas, F.J., &Córdova, A. (2000). Iron distribution in different tissues in rats following exercise. Biological Trace Element Research, 73(3), 259-268. https://doi.org/10.1385/BTER:73:3:259
  • NIST Standard reference materials catalog. (1996). NIST Special Publication 260, Standards Reference Material Programme, U.S. Department of Commerce, Gaithersburg, MD 20899-0001, USA
  • Ozturk, A., Baltaci, A.K., Mogulkoc, R., Oztekin, E., Sivrikaya, A., Kurtoglu, E., & Kul, A. (2003). Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissues of rats performing swimming exercise. Biological Trace Element Research,94(2), 157-166. https://doi.org/10.1385/BTER:94:2:157
  • Patlar, S., Gulnar, U., Baltaci, A.K., & Mogulkoc, R. (2014) Effect of nocturnal exhaustion exercise on the metabolism of selected elements. Archives of Biological Sciences, 66(4),1595-1601. https://doi.org/10.2298/ABS1404595P
  • Pingitore, A., Lima, G.P., Mastorci, F., Quinones, A., Iervasi, G., & Vassalle, C. (2015). Exercise and oxidative stress: potential effects of antioxidant dietary strategies in sports. Nutrition, 31(7-8), 916-922. https://doi.org/10.1016/j.nut.2015.02.005
  • Schrauwen, P., & Timmers, S. (2014). Can resveratrol help to maintain metabolic health? The Proceedings of the Nutrition Society, 73(2), 271-277. https://doi.org/10.1017/S0029665113003856
  • Sharman, J.E., La Gerche, A., & Coombes, J.S. (2015). Exercise and cardiovascular risk in patients with hypertension. American Journal of Hypertension, 28(2), 147-158. https://doi.org/10.1093/ajh/hpu191
  • Sivrikaya, A., Akil, M., Bicer, M., Kilic, M., Baltaci, A.K., & Mogulkoc, R. (2013). The effect of selenium supplementation on elements distribution in liver of rats subject to strenuous swimming. Bratislavské Lekárske Listy,114(1), 12-14. https://doi.org/10.4149/bll_2013_003
  • Sivrikaya, A., Bicer, M., Akil, M., Baltaci, A.K., & Mogulkoc, R. (2012). Effects of zinc supplementation on the element distribution in kidney tissue of diabetic rats subjected to acute swimming. Biological Trace Element Research,147(1-3), 195-199. https://doi.org/10.1007/s12011-011-9284-6
  • Skrajnowska, D., Bobrowska-Korczak, B., Tokarz, A., Bialek, S., Jezierska, E., & Makowska, J. (2013). Copper and resveratrol attenuates serum catalase, glutathione peroxidase, and element values in rats with DMBA-induced mammary carcinogenesis. Biological Trace Element Research,156(1-3), 271-278. https://doi.org/10.1007/s12011013-9854-x
  • Wells, I.C. (2008). Evidence that the etiology of the syndrome containing type 2 diabetes mellitus results from abnormal magnesium metabolism. Canadian Journal of Physiology and Pharmacology, 86(1-2), 16-24. https://doi.org/10.1139/y07-122
  • Zhao, L., Wang, Y., Wang, Z., Xu, Z., Zhang Q., & Yin, M. (2015) Effects of dietary resveratrol on excess-iron-induced bone loss via antioxidative character. The Journal of Nutritional Biochemistry, 26(11), 1174-1182. https://doi.org/10.1016/j.jnutbio.2015.05.009
Toplam 30 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Spor Hekimliği
Bölüm Makaleler
Yazarlar

Abdulkerim Kasım Baltacı 0000-0003-2461-1212

Dilek Arslangil 0000-0003-4413-2833

Saltuk Buğra Baltacı 0000-0002-9752-7508

Rasim Moğulkoç 0000-0001-6155-6780

Ömer Ünal 0000-0002-4816-830X

Proje Numarası SUBAPK; project no. 1420132013
Erken Görünüm Tarihi 25 Kasım 2023
Yayımlanma Tarihi 31 Aralık 2023
Gönderilme Tarihi 8 Mart 2023
Kabul Tarihi 5 Temmuz 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 18 Sayı: 2

Kaynak Göster

APA Baltacı, A. K., Arslangil, D., Baltacı, S. B., Moğulkoç, R., vd. (2023). Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats. CBÜ Beden Eğitimi Ve Spor Bilimleri Dergisi, 18(2), 399-410. https://doi.org/10.33459/cbubesbd.1261924
AMA Baltacı AK, Arslangil D, Baltacı SB, Moğulkoç R, Ünal Ö. Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats. CBÜ BESBD. Aralık 2023;18(2):399-410. doi:10.33459/cbubesbd.1261924
Chicago Baltacı, Abdulkerim Kasım, Dilek Arslangil, Saltuk Buğra Baltacı, Rasim Moğulkoç, ve Ömer Ünal. “Resveratrol Supplementation Is Associated With Elemental Metabolism in Some Tissues of Acute Swimming Rats”. CBÜ Beden Eğitimi Ve Spor Bilimleri Dergisi 18, sy. 2 (Aralık 2023): 399-410. https://doi.org/10.33459/cbubesbd.1261924.
EndNote Baltacı AK, Arslangil D, Baltacı SB, Moğulkoç R, Ünal Ö (01 Aralık 2023) Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats. CBÜ Beden Eğitimi ve Spor Bilimleri Dergisi 18 2 399–410.
IEEE A. K. Baltacı, D. Arslangil, S. B. Baltacı, R. Moğulkoç, ve Ö. Ünal, “Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats”, CBÜ BESBD, c. 18, sy. 2, ss. 399–410, 2023, doi: 10.33459/cbubesbd.1261924.
ISNAD Baltacı, Abdulkerim Kasım vd. “Resveratrol Supplementation Is Associated With Elemental Metabolism in Some Tissues of Acute Swimming Rats”. CBÜ Beden Eğitimi ve Spor Bilimleri Dergisi 18/2 (Aralık 2023), 399-410. https://doi.org/10.33459/cbubesbd.1261924.
JAMA Baltacı AK, Arslangil D, Baltacı SB, Moğulkoç R, Ünal Ö. Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats. CBÜ BESBD. 2023;18:399–410.
MLA Baltacı, Abdulkerim Kasım vd. “Resveratrol Supplementation Is Associated With Elemental Metabolism in Some Tissues of Acute Swimming Rats”. CBÜ Beden Eğitimi Ve Spor Bilimleri Dergisi, c. 18, sy. 2, 2023, ss. 399-10, doi:10.33459/cbubesbd.1261924.
Vancouver Baltacı AK, Arslangil D, Baltacı SB, Moğulkoç R, Ünal Ö. Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats. CBÜ BESBD. 2023;18(2):399-410.