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A Cause of Bicytopenia in Infancy: CMV

Yıl 2025, Cilt: 2 Sayı: 2, 138 - 140, 30.06.2025
https://doi.org/10.70058/cjm.1595997

Öz

Bicytopenia is frequently observed in the pediatric population as a result of transient bone marrow suppression, which may occur following vaccination or as a consequence of viral infections, including influenza, Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Symptoms of CMV infection, one of these agents, vary according to age and host immune competence. Although it is usually asymptomatic in healthy children, it can cause various infectious clinical presentations. In immunocompromised patients, it may cause pneumonia, retinitis, hepatitis, fever, thrombocytopenia and leukopenia. Here, we present a 4-month-old girl who was investigated for bicytopenia and subsequently diagnosed with CMV infection.

Proje Numarası

1595997

Kaynakça

  • Plosa EJ, Esbenshade JC, Fuller MP, Weitkamp JH. Cytomegalovirus infection. Pediatr Rev. 2012;33(4):156-163. doi:10.1542/pir.33-4-156
  • Kimberlin D.W.(Editor) Red Book Atlas of Pediatric Infectious Diseases. American Academy of Pediatrics; 2018-2021.
  • Vijayakrishnan, G., Thambi, R., & Sankar, S. A. (2020). year study of clinico hematological profile of bicytopenia and pancytopenia in paediatric patients attending a tertiary hospital in South India. IJPO, 7, 207-11.
  • Singh S, Roach V, Katoch P. Clinico Haematological Profile in Paediatric Patients with Bicytopenia and Pancytopenia in a Tertiary Care Referral Centre of North India. Journal of Advances in Medicine and Medical Research, 2021; 33(18): 57-63.
  • Kumar G, Verma S, Chavan S, Gupta A, Avuthu OPR, Mane S, Pathak N. Study of Clinicoetiological Spectrum of Bicytopenia and Pancytopenia in Hospitalized Children. Cureus. 2024; 16(8); e66255.
  • Yalaki Z, İçöz S, Arikan FI, Alioglu B, Dallar YB. Our Experience with Bicytopenia in Patients Treated at the Ankara Hospital Pediatric Clinic. J Pediatr Inf. 2014; 8(1): 23.
  • Celkan T, Koç BŞ. Approach to the patient with neutropenia in childhood. Turk Pediatri Ars. 2015;50(3):136-144. Published 2015 Sep 1. doi:10.5152/TurkPediatriArs.2015.2295
  • Tokgöz H,Çalışkan Ü. Hematologic manifestations of infectious diseases in children. Selçuk Tıp Dergisi. 2017; 33(3): 63-66.

Süt Çocukluğu Döneminde Bir Bisitopeni Nedeni: CMV

Yıl 2025, Cilt: 2 Sayı: 2, 138 - 140, 30.06.2025
https://doi.org/10.70058/cjm.1595997

Öz

Bisitopeni pediatrik popülasyonda sıklıkla İnfluenza, Ebstein-Barr virüs (EBV), sitomegalovirüs (CMV) gibi viral enfeksiyonların ardından ya da aşı uygulamaları sonrasında kemik iliğinin geçici baskılanması ile karşımıza çıkar. Bu etkenlerden olan CMV enfeksiyonunun belirtileri ise yaşa ve konak immün yeterliliğine göre değişir. Sağlıklı çocuklarda genellikle asemptomatik görülmekle birlikte çeşitli enfeksiyöz klinik tablolara sebep olabilir. İmmun sistemi baskılanmış kişilerde pnömoni, retinit, hepatit, ateş, trombositopeni ve lökopeni gibi tablolara yol açabilir. Burada bisitopeni sebebiyle araştırılan ve CMV enfeksiyonu saptanan 4 aylık bir kız hastayı sunduk.

Proje Numarası

1595997

Kaynakça

  • Plosa EJ, Esbenshade JC, Fuller MP, Weitkamp JH. Cytomegalovirus infection. Pediatr Rev. 2012;33(4):156-163. doi:10.1542/pir.33-4-156
  • Kimberlin D.W.(Editor) Red Book Atlas of Pediatric Infectious Diseases. American Academy of Pediatrics; 2018-2021.
  • Vijayakrishnan, G., Thambi, R., & Sankar, S. A. (2020). year study of clinico hematological profile of bicytopenia and pancytopenia in paediatric patients attending a tertiary hospital in South India. IJPO, 7, 207-11.
  • Singh S, Roach V, Katoch P. Clinico Haematological Profile in Paediatric Patients with Bicytopenia and Pancytopenia in a Tertiary Care Referral Centre of North India. Journal of Advances in Medicine and Medical Research, 2021; 33(18): 57-63.
  • Kumar G, Verma S, Chavan S, Gupta A, Avuthu OPR, Mane S, Pathak N. Study of Clinicoetiological Spectrum of Bicytopenia and Pancytopenia in Hospitalized Children. Cureus. 2024; 16(8); e66255.
  • Yalaki Z, İçöz S, Arikan FI, Alioglu B, Dallar YB. Our Experience with Bicytopenia in Patients Treated at the Ankara Hospital Pediatric Clinic. J Pediatr Inf. 2014; 8(1): 23.
  • Celkan T, Koç BŞ. Approach to the patient with neutropenia in childhood. Turk Pediatri Ars. 2015;50(3):136-144. Published 2015 Sep 1. doi:10.5152/TurkPediatriArs.2015.2295
  • Tokgöz H,Çalışkan Ü. Hematologic manifestations of infectious diseases in children. Selçuk Tıp Dergisi. 2017; 33(3): 63-66.
Toplam 8 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri (Diğer)
Bölüm Case Reports
Yazarlar

Havva Özüm Kolsuz 0000-0001-9100-9411

Handan Ayhan Akoğlu 0000-0001-9074-8466

Proje Numarası 1595997
Yayımlanma Tarihi 30 Haziran 2025
Gönderilme Tarihi 6 Aralık 2024
Kabul Tarihi 16 Ocak 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 2 Sayı: 2

Kaynak Göster

Vancouver Kolsuz HÖ, Akoğlu HA. A Cause of Bicytopenia in Infancy: CMV. Cerasus J Med. 2025;2(2):138-40.