Araştırma Makalesi
BibTex RIS Kaynak Göster

FARE KARACİĞER DOKUSUNDA YEŞİL ÇAY (Camellia sinensis L.) ve MAYDANOZ’UN (Petroselinum crispum) MDA ve GSH DÜZEYLERİ ÜZERİNE ETKİLERİNİN ARAŞTIRILMASI

Yıl 2015, Cilt: 2 Sayı: 1, 65 - 72, 31.12.2015

Öz

In this study, it has been tried to be searched the effects of green tea
(Camellia sinensis L.) and parsley (Petroselinum crispum) that is known
their antioxidant features on levels of MDA and GSH on mice liver tissue.

In the study, total 24 Swiss albino mice has been used that 8 of them are
control and 16 of them are practise. By dividing 16 mice into 2 different
groups in practise group, for 1.group 3 g/L green tea and for 2.group 0,464
g/kg parsley have been given orally during 8 weeks.





As a results, by increasing GSH levels on groups given green tea and
parsley to control group (p<0,05), but in MDA levels has not been seen a
significant decreasing as statistical. When compared the group given green tea
to parsley, it has been observed that green tea has increased more GSH level in
comparison with parsley as statistical (p<0,05). 

Kaynakça

  • 1 . Forouzan M , Hossein N, Aliakbar , Javad A M, Mahdi S: Effects of Herbal Medicine on Male Infertility, Anatomical Sciences, 10;4, 1-16. 2013.
  • 2. Haidari F, Omidian K, Rafiei H, Mehdi Z and Shahi M M: Green Tea (Camellia sinensis) Supplementation to Diabetic Rats Improves Serum and Hepatic Oxidative Stress Markers, Iran J Pharm Res. Winter; 12(1): 109–114, 2013.
  • 3 . Vinson JA, Dabbagh YA, Serry MM, Jang J: Plant flavonoids, especially tea flavonoids, are powerfull antioxidants using an in vitro oxidation model for heart disease. J Agric Food Chem, 43, 2800-2802, 1995.
  • 4 . Craig WJ: Health-promoting properties of common herbs. Am J Clin Nutr 70, 491-499, 1999.
  • 5 . Yang YC, Lu FH, Wu JS, Wu CH, Chang CJ: The protective effect of habitual tea consumption on hypertension. Arch Intern Med, 164, 1534-1540, 2004.
  • 6 . Moline J, Bukharovich IF, Wolff MS, Philips R: Dietary flavonoids and hypertension: Is there a link? Med Hypotheses, 55, 306-309, 2000.
  • 7 . Yang CS, Landau JM: Effects of Tea Consumption on Nutrion and Health. American Society for Nutritional Sciences, 130, 2409-2412, 2000.
  • 8 . Li C, Xie B: Evaluation of the Antioxidant and Pro-oxidant Effects of Tea oxypolimers. J Agric Food Chem, 48, 6362-6366, 2000.
  • 9 . Koo MW, Cho CH: Pharmacological effects of green tea on the gastrointestinal system. Eur J Pharmacol, 500, 177-85, 2004.
  • 10 . Sabu MC, Smitha K, Ramadasan K: Anti-diabetic activity of green tea polyphenols and their role in reducing oxidative stres in experimental diabetes. Journal of Ethnopharmacology, 83, 109-116, 2002.
  • 11. Allessio HM, Hagerman AE, Romanello M, Carando S, Threlkeld MS, Rogers J, Dimitrova Y, Muhammed S, Wiley RL: Consumption of green tea protects rats from exercise induced oxidative stres in kidney and liver. Nutrition Research, 22, 1177-1188, 2000.
  • 12. Klein EA: Chemoprevention of prostate cancer. Crit Rev Oncol/Hematol, 54, 1-10, 2005.
  • 13. Jian L, Xie LP, Lee AH, Binns CW: Protective effect of green tea againts prostate cancer: A case-control study in southeast China. Int J Cancer, 108, 130-135, 2004.
  • 14. Skrzydlewska E, Ostrowska J, Farbiszewski R, Michalak K: Protective effect of green tea against lipid peroxidation in the rat liver, blood serum and the brain, Phytomedicine, 9, 232-238, 2002.
  • 15. Öztürk N, Tunalıer Z, Koşar M, Başer KHC: Petroselinum crispum, Anethum graveolens ve Eruca Sativa’nın Antioksidan Etki ve Fenolik Bileşikler Yönünden İncelenmesi. 14.Bitkisel İlaç Hammaddeleri Toplantısı, Bildiriler, 29-31 Mayıs 2002.
  • 16. Ali-Shtayeh MS, Yaniv Z, Mahajna J: Ethnobotanical survey in the Palestinian area: a classification of the healing. J Ethnopharm, 73, 221-232, 2000.
  • 17. De M, De AK, Banerjee AB: Antimicrobial screening of some indian spices. Phytotherapy Research, 13(7), 616-618, 1999.
  • 18. Sacan OO, Yanardağ R, Orak H, Özgey Y, Yerat A, Tunali T: Effect of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin induced, diabetic rats, Journal of Ethnopharmacology, 104, 175-181, 2006.
  • 19. Placer ZA, Cushman LL, Johnson BC: Estimation of Product of Lipid Peroxidation (Malonyldialdehyde) in Biochemical Systems. Anal Biochem, 16, 359-364, 1966.
  • 20. Sedlak J, Lindsay RH: Estimation of Total Protein-bound and Non-protein Sülfhdryl Groups in Tissue with Ellman’s Reagent. Anal Biochem, 25, 192-205, 1968.
  • 21. Augustyniak A, Waszkiewicz E, Skrzydlewska E: Preventive action of green tea from changes in the liver antioxidant abilities of different aged rats intoxicated with ethanol. Nutrition, 21, 925-932, 2005.
  • 22. Ostrowska J, Lucjaz W, Kasacka I, Rozanski A, Skrzydlewska E: Green tea protects againts ethanol-induced lipid peroxidation in rat organs. Alcohol, 32, 25-32, 2004.
  • 23. Wong Peter YY, Kitts DD: Studies on the dual antioxidant and antibacterial properties of parsley (Petroselinum crispum) and cilantro (Coriandrum sativum) extracts. Food Chemistry, 97, 505-515, 2006.
Yıl 2015, Cilt: 2 Sayı: 1, 65 - 72, 31.12.2015

Öz

Kaynakça

  • 1 . Forouzan M , Hossein N, Aliakbar , Javad A M, Mahdi S: Effects of Herbal Medicine on Male Infertility, Anatomical Sciences, 10;4, 1-16. 2013.
  • 2. Haidari F, Omidian K, Rafiei H, Mehdi Z and Shahi M M: Green Tea (Camellia sinensis) Supplementation to Diabetic Rats Improves Serum and Hepatic Oxidative Stress Markers, Iran J Pharm Res. Winter; 12(1): 109–114, 2013.
  • 3 . Vinson JA, Dabbagh YA, Serry MM, Jang J: Plant flavonoids, especially tea flavonoids, are powerfull antioxidants using an in vitro oxidation model for heart disease. J Agric Food Chem, 43, 2800-2802, 1995.
  • 4 . Craig WJ: Health-promoting properties of common herbs. Am J Clin Nutr 70, 491-499, 1999.
  • 5 . Yang YC, Lu FH, Wu JS, Wu CH, Chang CJ: The protective effect of habitual tea consumption on hypertension. Arch Intern Med, 164, 1534-1540, 2004.
  • 6 . Moline J, Bukharovich IF, Wolff MS, Philips R: Dietary flavonoids and hypertension: Is there a link? Med Hypotheses, 55, 306-309, 2000.
  • 7 . Yang CS, Landau JM: Effects of Tea Consumption on Nutrion and Health. American Society for Nutritional Sciences, 130, 2409-2412, 2000.
  • 8 . Li C, Xie B: Evaluation of the Antioxidant and Pro-oxidant Effects of Tea oxypolimers. J Agric Food Chem, 48, 6362-6366, 2000.
  • 9 . Koo MW, Cho CH: Pharmacological effects of green tea on the gastrointestinal system. Eur J Pharmacol, 500, 177-85, 2004.
  • 10 . Sabu MC, Smitha K, Ramadasan K: Anti-diabetic activity of green tea polyphenols and their role in reducing oxidative stres in experimental diabetes. Journal of Ethnopharmacology, 83, 109-116, 2002.
  • 11. Allessio HM, Hagerman AE, Romanello M, Carando S, Threlkeld MS, Rogers J, Dimitrova Y, Muhammed S, Wiley RL: Consumption of green tea protects rats from exercise induced oxidative stres in kidney and liver. Nutrition Research, 22, 1177-1188, 2000.
  • 12. Klein EA: Chemoprevention of prostate cancer. Crit Rev Oncol/Hematol, 54, 1-10, 2005.
  • 13. Jian L, Xie LP, Lee AH, Binns CW: Protective effect of green tea againts prostate cancer: A case-control study in southeast China. Int J Cancer, 108, 130-135, 2004.
  • 14. Skrzydlewska E, Ostrowska J, Farbiszewski R, Michalak K: Protective effect of green tea against lipid peroxidation in the rat liver, blood serum and the brain, Phytomedicine, 9, 232-238, 2002.
  • 15. Öztürk N, Tunalıer Z, Koşar M, Başer KHC: Petroselinum crispum, Anethum graveolens ve Eruca Sativa’nın Antioksidan Etki ve Fenolik Bileşikler Yönünden İncelenmesi. 14.Bitkisel İlaç Hammaddeleri Toplantısı, Bildiriler, 29-31 Mayıs 2002.
  • 16. Ali-Shtayeh MS, Yaniv Z, Mahajna J: Ethnobotanical survey in the Palestinian area: a classification of the healing. J Ethnopharm, 73, 221-232, 2000.
  • 17. De M, De AK, Banerjee AB: Antimicrobial screening of some indian spices. Phytotherapy Research, 13(7), 616-618, 1999.
  • 18. Sacan OO, Yanardağ R, Orak H, Özgey Y, Yerat A, Tunali T: Effect of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin induced, diabetic rats, Journal of Ethnopharmacology, 104, 175-181, 2006.
  • 19. Placer ZA, Cushman LL, Johnson BC: Estimation of Product of Lipid Peroxidation (Malonyldialdehyde) in Biochemical Systems. Anal Biochem, 16, 359-364, 1966.
  • 20. Sedlak J, Lindsay RH: Estimation of Total Protein-bound and Non-protein Sülfhdryl Groups in Tissue with Ellman’s Reagent. Anal Biochem, 25, 192-205, 1968.
  • 21. Augustyniak A, Waszkiewicz E, Skrzydlewska E: Preventive action of green tea from changes in the liver antioxidant abilities of different aged rats intoxicated with ethanol. Nutrition, 21, 925-932, 2005.
  • 22. Ostrowska J, Lucjaz W, Kasacka I, Rozanski A, Skrzydlewska E: Green tea protects againts ethanol-induced lipid peroxidation in rat organs. Alcohol, 32, 25-32, 2004.
  • 23. Wong Peter YY, Kitts DD: Studies on the dual antioxidant and antibacterial properties of parsley (Petroselinum crispum) and cilantro (Coriandrum sativum) extracts. Food Chemistry, 97, 505-515, 2006.
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Bölüm Makaleler
Yazarlar

Aysel Güven Bu kişi benim

Engin Erkan Bu kişi benim

Yayımlanma Tarihi 31 Aralık 2015
Gönderilme Tarihi 9 Mart 2015
Kabul Tarihi 16 Haziran 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 2 Sayı: 1

Kaynak Göster

APA Güven, A., & Erkan, E. (2015). FARE KARACİĞER DOKUSUNDA YEŞİL ÇAY (Camellia sinensis L.) ve MAYDANOZ’UN (Petroselinum crispum) MDA ve GSH DÜZEYLERİ ÜZERİNE ETKİLERİNİN ARAŞTIRILMASI. Caucasian Journal of Science, 2(1), 65-72.

dizin1.png dizin2.png dizin3.png  dizin5.png dizin6.png dizin7.png