Effects of Black Carrot Juice on Liver Lipid Peroxidation and Antioxidant Enzymes in Acutely Exercised Rats

Yıl 2024, Cilt: 8 Sayı: 2, 115 - 119

Kürşat Yusuf Aytaç , Ahmet Özkaya , Mustafa Daban

https://doi.org/10.31594/commagene.1595158

Öz

In this study, the effects of black carrot juice on acutely exercised rat liver tissues were investigated. Rats were formed into Control (C), Black carrot juice (S), Acute exercise (E) and Black carrot juice + Acute exercise (SE) groups. The acute exercise program was applied on a treadmill device. Malondialdehyde (MDA) and Glutathione (GSH) levels were examined in the rat liver tissues obtained at the end of the experimental process, while Glutathione reductase (GR), glutathione-S-transferase (GST) and Carboxyl esterase (Ces) enzyme activity levels were measured. While MDA, GST and Ces enzyme activity levels in the E group increased compared to the K group, GR and GSH levels decreased compared to the K group. GST and Ces enzyme activities in the S group increased compared to the K group. While GSH level in the SE group increased compared to the E group, GST enzyme activity and MDA levels decreased. As a result, we think that black carrot juice prevents lipid peroxidation and has a supportive effect on the antioxidant enzyme system on the liver tissues of rats subjected to acute exercise

Anahtar Kelimeler

Exercise, black carrot, lipid peroxidation, antioxidant enzyme

Proje Numarası

SBFYL/2024-0002

Akut Egzersiz Yaptırılan Sıçanlarda Karaciğerlerindeki Lipit Peroksidasyon ve Antioksidan Enzimleri Üzerine Siyah Havuç Suyunun Etkileri

Öz

Bu çalışmada, akut egzersiz yaptırılan sıçanların karaciğerlerinin dokuları üzerine siyah havuç suyunun etkileri araştırıldı. Sıçanlar Kontrol (K), Siyah havuç suyu (S), Akut egzersiz (E) ve Siyah havuç suyu + Akut egzersiz (SE) grupları oluşturuldu. Akut egzersiz programı treadmill cihazında uygulamalar yapıldı. Deneysel süreç sonunda elde edilen sıçan karaciğer dokularında malondialdehit (MDA) ve Glutatyon (GSH) düzeyleri incelenirken, Glutatyon redüktaz (GR), Glutatyon-Stransferaz (GST) ve Karboksil esteraz (Ces) enzim aktivite düzeyleri ölçüldü. E grubu MDA, GST ve Ces enzim aktivite düzeyleri K grubuna göre artarken, GR ve GSH düzeyleri ise K grubuna göre azaldı. S grubu GST ve Ces enzim aktiviteleri K grubuna göre arttı. SE grubu GSH düzeyi E grubuna göre artarken, GST enzim aktivite ve MDA düzeyleri azaldı. Sonuç olarak, akut egzersiz uygulanan sıçanların karaciğer dokuları üzerine siyah havuç suyunun lipid peroksidasyonu engellediği, antioksidan enzim sistemini destekleyici etkisinin olduğunu düşünmekteyiz.

Anahtar Kelimeler

Akut Egzersiz Yaptırılan Sıçanlarda Karaciğerlerindeki Lipit Peroksidasyon ve Antioksidan Enzimleri Üzerine Siyah Havuç Suyunun Etkileri, Egzersiz, Siyah havuç,, lipit peroksidasyon, antioksidan enzim

Etik Beyan

Bu çalışma, hayvan deneylerinin etik standartlarına uygun olarak yapılmıştır. Çalışma için yasal araştırma etik kurul onay izinleri Adıyaman Üniversitesi Deney Hayvanları Etik Kurulu'ndan alınmıştır (No: 2024/40)

Destekleyen Kurum

Adıyaman üniversitesi

Proje Numarası

SBFYL/2024-0002

Teşekkür

Bu çalışma Adıyaman Üniversitesi Bilimsel Araştırma Projeleri Birimi (BAP) tarafından SBFYL/2024-0002 no.lu proje kapsamında desteklenmiştir.

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