Postural stability in early Parkinson’s disease: effect of cognitive dual-tasking
Öz
Purpose: The primary aim of this study is to evaluate postural stability by using a static posturography in patients with early Parkinson’s disease (PD). Secondly, this paper addresses the need for illustrating the effect of dual-tasking on postural stability in early PD patients.
Materials and Methods: Twenty-nine early PD patients with maximum 5 years of disease duration were included in this study. The selected group had no clinical PI while their age- and sex-matched healthy controls were carried out. Neurological examination and mini-mental state examination (MMSE) were performed in all subjects. Unified Parkinson Disease Rating Scale (UPDRS) and modified Hoehn and Yahr (H&Y) scores were recorded in PD patients. Postural stability was assessed in all subjects on a static posturography platform under three different conditions: eyes open, eyes closed and a cognitive task of producing words with given letters.
Results: The mean age of the PD was 59.2±10.5 whereas the control groups mean age was 56.3±7.6 (p>0.05). The female-male ratio was 9/20 in the PD and 12/17 in the control group. There was no important difference between the two groups in terms of demographic characteristics. In the PD group, the mean UPDRS was 12.8±4.9. The patients were mostly receiving polytherapy.
Eye closure and cognitive task caused an increase in most sway parameters in both groups.
Conclusion: Early PD patients on medication, postural stability is preserved and cognitive dual-tasking does not affect postural stability in these patients in the early stage.
Anahtar Kelimeler
Dual-task interference, cognitive task, Parkinson’s disease, postural instability, static posturography
Kaynakça
- 1. Palakurthi B, Burugupally SP. Postural Instability in Parkinson’s Disease: A Review. Brain Sci. 2019 Sep; 18;9(9): 239.
- 2. Viseux FJF, Delval A, Defebvre L, et al. Postural instability in Parkinson's disease: Review and bottom-up rehabilitative approaches. Neurophysiol Clin. 2020 Nov;50(6):479-487.
- 3. Pérez-Sánchez JR, Grandas F. Early Postural Instability in Parkinson's Disease: A Biomechanical Analysis of the Pull Test. Parkinsons Dis. 2019; 2019: 6304842.
- 4. Chastan N, Debono B, Maltête D, et al. Discordance between measured postural instability and absence of clinical symptoms inParkinson's disease patients in the early stages of the disease. Mov Disord, 2008; 23: 366-372.
- 5. You S, Kim HA, Lee H. Association of Postural Instability with Autonomic Dysfunction in Early Parkinson's Disease. J Clin Med. 2020 Nov 23;9(11):3786.
- 6. Panyakaew P, Anan C, Bhidayasiri R. Visual deprivation elicits subclinical postural inflexibilities in early Parkinson's disease. J Neurol Sci. 2015 Feb 15;349(1-2):214-9.
- 7. Tsang WW, Chan VW, Wong HH, et al. The effect of performing a dual-task on postural control and selective attention of older adults when stepping backward. J Phys Ther Sci. 2016;28(10):2806-11.
- 8. Marchese R, Bove M, Abbruzzese G. Effect of cognitive and motor tasks on postural stability in Parkinson’s disease: a posturographic study, Mov Disord, 2003; 18:652-660.
- 9. Bekkers EMJ, Dockx K, Devan S, et al. The Impact of Dual-Tasking on Postural Stability in People With Parkinson's Disease With and Without Freezing of Gait. Neurorehabil Neural Repair. 2018 Feb;32(2):166-174.
- 10. Plotnik M, Giladi N, Dagan Y, et al. Postural instability and fall risk in Parkinson's disease: impaired dual tasking, pacing, and bilateral coordination of gait during the "ON" medication state. Exp Brain Res. 2011 May;210(3-4):529-38.
