Giant cell tumor of the temporal bone
Öz
Giant cell tumor (GCT) arises from undifferentiated mesenchymal cells of the bone marrow. GCT, a benign and locally aggressive tumor, is more commonly seen in the metaphysis of long bones. It may cause local bone destruction, recurrence, and pulmonary metastases (~1%). A 15-year-old male patient was admitted with complaints of swelling on the right face, a headache that has persisted for one year and progressively worsened in the last three months, and hearing loss. Craniotomy and total tumor excision were performed. Histopathological examination revealed a giant cell tumor of the bone. We present a case of temporal bone GCT with its clinical and radiologic features.
Anahtar Kelimeler
Kaynakça
- Akyigit A, Karlidag T, Sakallioglu Ö, Polat C, Keles E. Giant cell tumor of bone involving the temporomandibular joint and temporal bone. J Craniofac Surg 2014;25:1397-9.
- Sepulveda I, Alzerreca J, Villalobos P, Ulloa JP. Giant cell tumor of the temporal bone with skull base and middle ear extension. J Med Cases. 2021;12:149-51.
- Iizuka T, Furukawa M, Ishii H, Kasai M, Hayashi C, Arai H et al. Giant cell tumor of the temporal bone with direct invasion into the middle ear and skull base: a case report. Case Rep Otolaryngol. 2012:2012; 690148
- Kaya İ, Benzer M, Turhal G, Sercan G, Bilgen C, Kirazlı T. Giant Cell Tumor of the Temporal Bone and Skull Base: A Case Report. J Int Adv Otol. 2018;14:151-4.
- Jain S, Sam A, Yohannan DI, Kumar S, Joshi D, Kumar A. Giant cell tumor of the temporal bone—an unusual presentation. Clin Neurol Neurosurg. 2013;115:646-8.
- Borges BB, Fornazieri MA, Bezerra AP, Martins LA, Pinna Fde R, Voegels RL. Giant cell bone lesions in the craniofacial region: a diagnostic and therapeutic challenge. Int Forum Allergy Rhinol. 2012;2:501-6.
- Koo T, Danner C. A rare case of giant cell tumor of the temporal bone. Otolaryngology Case Reports. 2020;15:100160.
- Miller MA, Kesarwani P, Crane BT. Autophony in a patient with giant cell tumor of the temporal bone. Otol Neurotol. 2016;37:e238-9.
- Jain A, Singh I, Shankar R, Varshney D. Giant cell tumour of temporal bone and infratemporal fossa: a rare case. Head Neck Pathol. 2020;14:503-6.
- Czerniak B. Giant cell lesions. In Dorfman and Czerniak'sBone Tumors (Eds HD Dorfman, B Czerniak):692-759.. Philadelphia, Elsevier Saunders, 2016
