Lost penis syndrome treated with duloxetine

Yıl 2024, Cilt: 49 Sayı: 4, 1098 - 1100, 30.12.2024

Doğancan Sönmez

https://doi.org/10.17826/cumj.1416014

Öz

Sexual dysfunction is a common condition in patients with major depression. It can negatively affect quality of life, self-confidence, and relationships with partners, especially in men. Common types of sexual dysfunction include lack of sexual desire, sexual arousal disorder, erectile dysfunction, and premature ejaculation. However, some psychopathologies are rarely reported in the literature but can cause sexual dysfunction, such as the lost penis syndrome. This study aims to contribute to the literature on these rare conditions by discussing the clinical course, diagnosis, and details of duloxetine treatment of a male patient who presented to the psychiatry outpatient clinic with the complaint of loss of sensation in the penis.

Anahtar Kelimeler

sexual dysfunction , Lost Penis Syndrome , duloxetine

Duloksetin ile tedavi edilen kayıp penis sendromu

Öz

Cinsel işlev bozukluğu majör depresyon hastalarında sık görülen bir durumdur. Özellikle erkeklerde yaşam kalitesini, özgüveni ve partnerlerle ilişkileri olumsuz etkileyebilir. Yaygın cinsel işlev bozukluğu türleri arasında cinsel istek eksikliği, cinsel uyarılma bozukluğu, erektil disfonksiyon ve erken boşalma yer alır. Bununla birlikte, literatürde nadiren bildirilen bazı psikopatolojiler, kayıp penis sendromu gibi cinsel işlev bozukluğuna neden olabilir. Bu çalışmada, peniste his kaybı şikayeti ile psikiyatri polikliniğine başvuran bir erkek hastanın klinik seyri, tanısı ve duloksetin tedavisinin detayları tartışılarak bu nadir durumlarla ilgili literatüre katkıda bulunulması amaçlanmıştır.

Anahtar Kelimeler

Duloksetin , kayıp penis sendromu , cinsel disfonksiyon

Kaynakça

• Doğan S. Sexual dysfunctions, depression and antidepressants. Journal of Mood Disorders. 2011;1:81-6.
• Angst J. Sexual problems in healthy and depressed persons. Int Clin Psychopharmacol. 1998;13:1-4.
• İncesu C. Cinsel işlevler ve cinsel işlev bozuklukları. Klinik Psikiyatri Dergisi. 2004;7:3-13.
• Colonnello E, Limoncin E, Ciocca G, Sansone A, Mollaioli D, Balercia G et al. The lost penis syndrome: a new clinical entity in sexual medicine. Sex Med Rev. 2022;10:113-29.
• Goldstein I, Goldstein S, Kim C, Blevins J, Komisaruk B. 130 Evaluation of bothersome/distressing penile numbness with orgasmic dysfunction: role of neuro-genital testing to localize the site of neurologic pathology. J Sex Med. 2020;17:36.
• Ntouros E, Ntoumanis A, Bozikas VP, Donias S, Giouzepas I, Garyfalos G. Koro-like symptoms in two Greek men. BMJ Case Rep. 2010;2010:bcr08.2008.0679.
• Ilechukwu STC. Magical penis loss in Nigeria: Report of a recent epidemic of a koro-like syndrome. Transcultural Psychiatric Research Review. 1992;29:91-108.
• Okechukwu CE. Shrinking and psychological disappearance of the penis: a salient psychocultural issue in Nigeria. Curr Med. 2021:19:117-8.
• Gündüz N, Turan H, Polat A. Persistent genital arousal disorder treated with duloxetine: a case report. Turk Psikiyatri Derg. 2019;30:67-70.
• Widyadharma IPE, Rau CPV, Pinzon RT, Yudiyanta Y, Indrayani AW, Purwata TE et al. Efficacy and safety of duloxetine in the treatment of chemotherapy induced peripheral neuropathy: a systematic review and meta-analysis. Malang Neurology Journal. 2020;7:48-55.
• Handa J, Sekiguchi M, Krupkova O, Konno S. The effect of serotonin-noradrenaline reuptake inhibitor duloxetine on the intervertebral disk-related radiculopathy in rats. Eur Spine J. 2016;25:877-87