Association of sarcopenia with age-related macular degeneration in the very elderly

Zeynep Katipoğlu; Bilal Katipoğlu; Meydan Turan

doi:10.17826/cumj.1625475

EN TR

Association of sarcopenia with age-related macular degeneration in the very elderly

Abstract

Purpose: The aim of this study was aimed to investigate the association between age-related macular degeneration and sarcopenia in the oldest-old population, constituting individuals aged ≥80 years. Material and Methods: This retrospective study was conducted in the ophthalmology and geriatric departments of a training and research hospital in 2023 and 2024. Participants aged ≥80 years who were admitted to the ophthalmology outpatient clinic for any reason were included in the study. Results: The study population comprised 311 individuals aged 80 years or older and the prevalence of age-related macular degeneration was 20.5% (n=64). The mean age of the patients diagnosed with age-related macular degeneration (AMD) was 85.9 years (±3.8), while the mean age of the control group was 85.8 years (±3.9). Of the patients diagnosed with age-related macular degeneration, 34 were female and 30 were male. The Deyo-Charlson Comorbidity Index (D-CCI) values were 1.77 in the age-related macular degeneration group and 1.85 in the control group. The prevalence of sarcopenia was significantly higher in patients with age-related macular degeneration (89.1% vs. 52.6%). Conclusion: This study demonstrates that sarcopenia is independently associated with age-related macular degeneration in the oldest-old population. These findings highlight the significance of sarcopenia management in the prevention and management of age-related macular degeneration.

Keywords

Sarcopenia , Age-related macular degeneration , Oxidative stress , Inflammation , Older adult

Çok yaşlılarda sarkopeni ile yaşla ilişkili makula dejenerasyonu arasındaki ilişki

Öz

Amaç: Bu çalışmada yaşa bağlı makula dejenerasyonu ile sarkopeni arasındaki ilişki en yaşlı popülasyonda (80 yaş ve üzeri) araştırılmıştır. Gereç ve Yöntem: Bu retrospektif çalışma, 2023-2024 yılları arasında bir eğitim araştırma hastanesinin oftalmoloji ve geriatri bölümünde yürütülmüştür. Herhangi bir nedenle oftalmoloji polikliniğine başvuran 80 yaş ve üzeri katılımcılar bu çalışmaya dahil edilmiştir. Bulgular: Çalışma popülasyonu 80 yaş ve üzeri 311 bireyden oluşmuştur ve yaşa bağlı makula dejenerasyonunun yaygınlığı %20,5'tir (n=64). Yaşa bağlı makula dejenerasyonu olan hastaların yaş ortalaması 85.9 (±3.8) iken kontrol grubunun yaş ortalaması 85.8(±3.9) idi. Yaşa bağlı makula dejenerasyonu olan hastaların 34 ü kadın, 30 u erkekti. Deyo-Charlson comorbidity index (D-CCI) değerleri yaşa bağlı makula dejenerasyonu grubunda 1.77 iken kontrol grubunda 1.85 idi. Sarkopeni prevalansının yaşa bağlı makula dejenerasyonu hastalarında belirgin şekilde daha yüksek olduğu gözlemlendi (%89,1'e karşı %52,6). Sonuç: Çalışmamız, sarkopeninin en yaşlı bireylerde yaşa bağlı makula dejenerasyonu ile ilişkili bağımsız bir değişken olduğunu göstermektedir. Bu bulgular, sarkopeni yönetiminin yaşa bağlı makula dejenerasyonunun önlenmesi ve yönetimindeki önemini vurgulamaktadır.

Anahtar Kelimeler

oksidatif stres , sarkopeni , yaşa bağlı makula dejenerasyon , inflamasyon

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Göz Hastalıkları

Bölüm

Araştırma Makalesi

Yazarlar

Zeynep Katipoğlu ^*
0000-0002-6935-3221
Türkiye

Bilal Katipoğlu
0000-0002-7235-7979
Türkiye

Meydan Turan
0000-0001-6593-9025
Türkiye

Yayımlanma Tarihi

30 Haziran 2025

Gönderilme Tarihi

23 Ocak 2025

Kabul Tarihi

15 Mayıs 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 50 Sayı: 2

DOI

https://doi.org/10.17826/cumj.1625475

IZ

https://izlik.org/JA57PP58XF

MLA

Katipoğlu, Zeynep, vd. “Association of sarcopenia with age-related macular degeneration in the very elderly”. Cukurova Medical Journal, c. 50, sy 2, Haziran 2025, ss. 341-6, doi:10.17826/cumj.1625475.

Cited By

Gender-Specific Impact of Cataracts on Geriatric Syndrome Burden in Solitary-Living Older Adults

OSMANGAZİ JOURNAL OF MEDICINE

https://doi.org/10.20515/otd.1783870

Bu eser Creative Commons Atıf-Gayriticari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Association of sarcopenia with age-related macular degeneration in the very elderly

Abstract

Keywords

Çok yaşlılarda sarkopeni ile yaşla ilişkili makula dejenerasyonu arasındaki ilişki

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster

Cited By

Gender-Specific Impact of Cataracts on Geriatric Syndrome Burden in Solitary-Living Older Adults