Association between attention deficit hyperactivity disorder and chronotype in adults with epilepsy

Kerim Uğur; Tunahan Sun; İrem Taşcı; Fatma Kartal

doi:10.17826/cumj.1686754

EN TR

Association between attention deficit hyperactivity disorder and chronotype in adults with epilepsy

Abstract

Purpose: This study aimed to determine the chronotype characteristics in adults with epilepsy, examine the relationship between chronotype and Attention Deficit Hyperactivity Disorder (ADHD), and compare ADHD symptom levels between patients with epilepsy and healthy controls. Materials and Methods: The study included 90 patients with epilepsy and 70 healthy controls, aged between 18 and 65 years. Sociodemographic and clinical data (seizure status, EEG, and MRI findings) were collected from the participants. The Morningness-Eveningness Questionnaire (MEQ), Adult ADHD Diagnosis and Evaluation Inventory, and Adult ADHD Self-Report Scale (ASRS) were administered. Results: A higher proportion of intermediate chronotypes was observed in the epilepsy group (68.9%) than in the control group (51.4%). ADHD symptom scores were higher in patients than in controls. Among patients with epilepsy, individuals with intermediate and evening chronotypes had significantly higher ADHD symptoms than those with morning chronotype. Although individuals with an evening chronotype had higher ADHD symptom levels than those with an intermediate chronotype, this difference was not statistically significant. Conclusion: The findings suggest that ADHD symptoms become more pronounced in patients with epilepsy as chronotype characteristics shift toward eveningness. Circadian features should be considered in the evaluation and management of ADHD comorbidity in adult patients with epilepsy.

Keywords

Epilepsy , Chronotype , Attention Deficit Hyperactivity Disorder , Adults , Sleep-Wake Cycle

Epilepsi tanılı yetişkinlerde dikkat eksikliği̇ ve hiperaktivite bozukluğu ile kronotip arasındaki ilişki

Öz

Amaç: Bu çalışmanın amacı, epilepsi tanılı yetişkin bireylerde kronotip özelliklerini belirlemek, kronotip ile Dikkat Eksikliği ve Hiperaktivite Bozukluğu (DEHB) arasındaki ilişkiyi incelemek ve epilepsi hastaları ile sağlıklı kontroller arasında DEHB belirti düzeylerini karşılaştırmaktı. Gereç ve Yöntem: Çalışmaya 18-65 yaş arası 90 epilepsi tanılı hasta ve 70 sağlıklı kontrol dahil edildi. Katılımcıların sosyodemografik ve klinik verileri (nöbet durumları, EEG ve MR bulguları) toplandı. Sabahçıl-Akşamcıl Anketi (MEQ), Erişkin DEHB Tanı ve Değerlendirme Envanteri ve Erişkin DEHB Öz Bildirim Ölçeği (ASRS) uygulandı. Bulgular: Epilepsi grubunda ara kronotip oranı (%68.9), kontrol grubuna (%51.4) göre daha yüksekti. DEHB belirti puanları epilepsi hastalarında sağlıklı kontrollerden anlamlı düzeyde daha yüksekti. Epilepsi hastaları arasında, sabahçıl kronotipe sahip bireylerle karşılaştırıldığında, ara ve akşamcıl kronotipe sahip bireylerin DEHB belirtileri anlamlı düzeyde daha yüksekti. Akşamcıl kronotipe sahip bireylerin DEHB belirti düzeyleri, ara kronotipe göre daha yüksek olsa da bu fark istatistiksel olarak anlamlı değildi. Sonuç: Bulgular, DEHB belirtilerinin epilepsi hastalarında kronotip özellikleri akşamcıl yöne kaydıkça daha belirgin hale geldiğini göstermektedir. Bu durum epilepsi tanılı erişkin hastalarda DEHB komorbiditesinin değerlendirilmesi ve yönetiminde sirkadiyen özelliklerin göz önünde bulundurulması gerektiğini göstermektedir.

Anahtar Kelimeler

Epilepsi , Kronotip , Dikkat Eksikliği Hiperaktivite Bozukluğu , Yetişkinler , Uyku-Uyanıklık Döngüsü

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Psikiyatri

Bölüm

Araştırma Makalesi

Yazarlar

Kerim Uğur
0000-0002-3131-6564
Türkiye

Tunahan Sun ^*
0000-0002-1383-3154
Türkiye

İrem Taşcı
0000-0001-7069-769X
Türkiye

Fatma Kartal
0000-0002-5379-0021
Türkiye

Yayımlanma Tarihi

30 Eylül 2025

Gönderilme Tarihi

29 Nisan 2025

Kabul Tarihi

15 Ağustos 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 50 Sayı: 3

DOI

https://doi.org/10.17826/cumj.1686754

IZ

https://izlik.org/JA89NG92GM

MLA

Uğur, Kerim, vd. “Association between attention deficit hyperactivity disorder and chronotype in adults with epilepsy”. Cukurova Medical Journal, c. 50, sy 3, Eylül 2025, ss. 806-18, doi:10.17826/cumj.1686754.

Bu eser Creative Commons Atıf-Gayriticari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Association between attention deficit hyperactivity disorder and chronotype in adults with epilepsy

Abstract

Keywords

Epilepsi tanılı yetişkinlerde dikkat eksikliği̇ ve hiperaktivite bozukluğu ile kronotip arasındaki ilişki

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster