Araştırma Makalesi
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Prevalence and clinical correlates of mesenteric panniculitis in urinary stone disease

Yıl 2025, Cilt: 50 Sayı: 4, 1084 - 1091, 22.12.2025
https://doi.org/10.17826/cumj.1749647

Öz

prevalence of mesenteric panniculitis in patients with urinary system calculi and identify factors, such as hydronephrosis and calculus location, that might be associated with the presence of mesenteric panniculitis.
Materials and Methods: In this retrospective observational study, the prevalence of mesenteric panniculitis was determined in 692 patients with urolithiasis using non-contrast-enhanced computed tomography imaging between 2017 and 2020. The grade of hydronephrosis and the level of urinary calculi were recorded for each patient, and statistical analysis was performed to assess the link between these features and mesenteric panniculitis.
Results: The prevalence of mesenteric panniculitis in patients with urolithiasis was 6.35% and it was associated with the presence of hydronephrosis. It was more common in patients who had both ureterolithiasis and nephrolithiasis with no statistically significant difference regarding in age, gender, or the presence of either only nephrolithiasis or only ureterolithiasis.
Conclusion: Mesenteric panniculitis is more common in patients with both ureterolithiasis and nephrolithiasis and can be easily diagnosed with non-contrast computed tomography imaging. Because the mesentery and urinary system share a common lymphatic drainage system, increased lymphatic drainage due to hydronephrosis has been shown to contribute to the development of mesenteric panniculitis.

Kaynakça

  • Buragina G, Magenta Biasina A, Carrafiello G. Clinical and radiological features of mesenteric panniculitis: a critical overview. Acta Biomed. 2019;90:411-22.
  • Sulbaran M, Chen FK, Farraye FA, Hashash JG. A Clinical Review of Mesenteric Panniculitis. Gastroenterol Hepatol. 2023;19:211-18.
  • Jackman SV, Maganty A, Wolfson AB, Burrows PK, MacPherson C, Vargas NM et al. Resolution of hydronephrosis and pain to predict stone passage for patients with acute renal colic. Urology. 2022;159:48-52.
  • Khan SR, Pearle MS, Robertson WG, Gambaro G, Canales BK, Doizi S et al. Kidney stones. Nat Rev Dis Primers. 2016;2:16008.
  • Ehrenpreis ED, Roginsky G, Gore RM. Clinical significance of mesenteric panniculitis-like abnormalities on abdominal computerized tomography in patients with malignant neoplasms. World J Gastroenterol. 2016;22(:10601-08.
  • Gunes SO, Akturk Y, Guldogan ES, Yilmaz KB, Ergun O, Hekimoglu B. Association between mesenteric panniculitis and non-neoplastic disorders. Clin Imaging. 2021;79:219-24.
  • Dadkhah A, Jafari S, Bagheri SM, Ebrahimi A. Association between mesenteric panniculitis and urolithiasis. Emerg Radiol. 2024;31:661-68.
  • Standring S, Gray H. Abdomen and pelvis. In Gray's Anatomy : The Anatomical Basis of Clinical Practice. (Eds NR Borley, JC Healy). Edinburgh, Churchill Livingstone, 2008.
  • Onen A. Grading of hydronephrosis: an ongoing challenge. Front Pediatr. 2020;8:458.
  • Schweistein H, Weintraub Y, Hornik-Lurie T, Haskiya H, Rave A, Glusman Bendersky A et al. Upper and lower endoscopic findings in mesenteric panniculitis patients: a case-control study. J Clin Med. 2024;13.
  • Ferrari TC, Couto CM, Vilaça TS, Xavier MA, Faria LC. An unusual presentation of mesenteric panniculitis. Clinics. 2008;63:843-4.
  • Coulier B. Mesenteric panniculitis. Part 2: prevalence and natural course: MDCT prospective study. JBR-BTR. 2011;94:241-6.
  • Issa I, Baydoun H. Mesenteric panniculitis: various presentations and treatment regimens. World J Gastroenterol. 2009;15:3827-30.
  • Oztan MO, Ozdemir T, Uncel M, Diniz G, Koyluoglu G. Isolated omental panniculitis in a child with abdominal pain: case report. Arch Argent Pediatr. 2016;114:e425.
  • Protin-Catteau L, Thiéfin G, Barbe C, Jolly D, Soyer P, Hoeffel C. Mesenteric panniculitis: review of consecutive abdominal MDCT examinations with a matched-pair analysis. Acta Radiol. 2016;57:1438-44.
  • Kuhrmeier A. Mesenteric lipodystrophy. Schweiz Med Wochenschr.1985;115:1218-24.
  • van Putte-Katier N, van Bommel EF, Elgersma OE, Hendriksz TR. Mesenteric panniculitis: prevalence, clinicoradiological presentation and 5-year follow-up. Br J Radiol. 2014;87:20140451.
  • Emory TS, Monihan JM, Carr NJ, Sobin LH. Sclerosing mesenteritis, mesenteric panniculitis and mesenteric lipodystrophy: a single entity? Am J Surg Pathol. 1997;21:392-8.
  • Meyyur Aravamudan V, Khan SR, Natarajan SK, Hussain I. The complex relationship between mesenteric panniculitis and malignancy - a holistic approach is still needed to understand the diagnostic uncertainties. Cureus. 2019;11:e5569.
  • Delgado Plasencia L, Rodríguez Ballester L, López-Tomassetti Fernández EM, Hernández Morales A, Carrillo Pallarés A, Hernández Siverio N. Mesenteric panniculitis: experience in our center. Rev Esp Enferm Dig. 2007;99:291-7.
  • Durst AL, Freund H, Rosenmann E, Birnbaum D. Mesenteric panniculitis: review of the leterature and presentation of cases. Surgery. 1977;81:203-11.
  • Patel N, Saleeb SF, Teplick SK. General case of the day. Mesenteric panniculitis with extensive inflammatory involvement of the peritoneum and intraperitoneal structures. Radiographics. 1999;19:1083-5.
  • Karmali RJ, Suami H, Wood CG, Karam JA. Lymphatic drainage in renal cell carcinoma: back to the basics. BJU Int. 2014;114:806-17.
  • Agur AMR, Lee MJ, Anderson JE. Lymphatic drainage of suprarenal glands,
  • Agur AMR, Dalley AF. Grant's Atlas of Anatomy. Baltimore, Williams & Wilkins, 1991.
  • Russell PS, Hong J, Windsor JA, Itkin M, Phillips ARJ. Renal lymphatics: anatomy, physiology, and clinical implications. Front Physiol. 2019;10:251.
  • Goodwin WE, Kaufman JJ. The renal lymphatics. I. Review of some of the pertinent literature. Urol Surv. 1956;6:305-29

Üriner taş hastalığında mezenterik pannikülitin prevalansı ve klinik belirleyicileri

Yıl 2025, Cilt: 50 Sayı: 4, 1084 - 1091, 22.12.2025
https://doi.org/10.17826/cumj.1749647

Öz

Amaç: Bu çalışmanın amacı, üriner sistem taşları olan hastalarda mezenterik pannikülitin prevalansını belirlemek ve hidronefroz ve taşın yeri gibi mezenterik pannikülitin varlığıyla ilişkili olabilecek faktörleri tanımlamaktır.
Gereç ve Yöntem: Bu retrospektif gözlemsel çalışmada, 2017 ile 2020 yılları arasında kontrastsız bilgisayarlı tomografi görüntüleme kullanılarak ürolitiyazisli 692 hastada mezenterik pannikülit prevalansı belirlenmiştir. Her hasta için hidronefroz derecesi ve üriner taşların seviyesi kaydedilmiş ve bu özellikler ile mezenterik pannikülit arasındaki bağlantıyı değerlendirmek için istatistiksel analiz yapılmıştır.
Bulgular: Ürolitiyazisli hastalarda mezenterik pannikülit prevalansı %6,35 idi ve hidronefroz varlığı ile ilişkiliydi. Üreterolitiazis ve nefrolitiazis olan hastalarda daha yaygındı, ancak yaş, cinsiyet (veya sadece nefrolitiazis veya sadece üreterolitiazis varlığı açısından istatistiksel olarak anlamlı bir fark yoktu.
Sonuç: Mezenterik pannikülit, hem üreterolitiyazis hem de nefrolitiyazis bulunan hastalarda daha yaygındır ve kontrastsız bilgisayarlı tomografi görüntüleme ile kolayca teşhis edilebilir. Mezenter ve üriner sistem ortak bir lenfatik drenajı paylaştığından, hidronefroza bağlı lenfatik drenajın artması mezenterik pannikülit gelişimine katkıda bulundugu gösterilmiştir.

Kaynakça

  • Buragina G, Magenta Biasina A, Carrafiello G. Clinical and radiological features of mesenteric panniculitis: a critical overview. Acta Biomed. 2019;90:411-22.
  • Sulbaran M, Chen FK, Farraye FA, Hashash JG. A Clinical Review of Mesenteric Panniculitis. Gastroenterol Hepatol. 2023;19:211-18.
  • Jackman SV, Maganty A, Wolfson AB, Burrows PK, MacPherson C, Vargas NM et al. Resolution of hydronephrosis and pain to predict stone passage for patients with acute renal colic. Urology. 2022;159:48-52.
  • Khan SR, Pearle MS, Robertson WG, Gambaro G, Canales BK, Doizi S et al. Kidney stones. Nat Rev Dis Primers. 2016;2:16008.
  • Ehrenpreis ED, Roginsky G, Gore RM. Clinical significance of mesenteric panniculitis-like abnormalities on abdominal computerized tomography in patients with malignant neoplasms. World J Gastroenterol. 2016;22(:10601-08.
  • Gunes SO, Akturk Y, Guldogan ES, Yilmaz KB, Ergun O, Hekimoglu B. Association between mesenteric panniculitis and non-neoplastic disorders. Clin Imaging. 2021;79:219-24.
  • Dadkhah A, Jafari S, Bagheri SM, Ebrahimi A. Association between mesenteric panniculitis and urolithiasis. Emerg Radiol. 2024;31:661-68.
  • Standring S, Gray H. Abdomen and pelvis. In Gray's Anatomy : The Anatomical Basis of Clinical Practice. (Eds NR Borley, JC Healy). Edinburgh, Churchill Livingstone, 2008.
  • Onen A. Grading of hydronephrosis: an ongoing challenge. Front Pediatr. 2020;8:458.
  • Schweistein H, Weintraub Y, Hornik-Lurie T, Haskiya H, Rave A, Glusman Bendersky A et al. Upper and lower endoscopic findings in mesenteric panniculitis patients: a case-control study. J Clin Med. 2024;13.
  • Ferrari TC, Couto CM, Vilaça TS, Xavier MA, Faria LC. An unusual presentation of mesenteric panniculitis. Clinics. 2008;63:843-4.
  • Coulier B. Mesenteric panniculitis. Part 2: prevalence and natural course: MDCT prospective study. JBR-BTR. 2011;94:241-6.
  • Issa I, Baydoun H. Mesenteric panniculitis: various presentations and treatment regimens. World J Gastroenterol. 2009;15:3827-30.
  • Oztan MO, Ozdemir T, Uncel M, Diniz G, Koyluoglu G. Isolated omental panniculitis in a child with abdominal pain: case report. Arch Argent Pediatr. 2016;114:e425.
  • Protin-Catteau L, Thiéfin G, Barbe C, Jolly D, Soyer P, Hoeffel C. Mesenteric panniculitis: review of consecutive abdominal MDCT examinations with a matched-pair analysis. Acta Radiol. 2016;57:1438-44.
  • Kuhrmeier A. Mesenteric lipodystrophy. Schweiz Med Wochenschr.1985;115:1218-24.
  • van Putte-Katier N, van Bommel EF, Elgersma OE, Hendriksz TR. Mesenteric panniculitis: prevalence, clinicoradiological presentation and 5-year follow-up. Br J Radiol. 2014;87:20140451.
  • Emory TS, Monihan JM, Carr NJ, Sobin LH. Sclerosing mesenteritis, mesenteric panniculitis and mesenteric lipodystrophy: a single entity? Am J Surg Pathol. 1997;21:392-8.
  • Meyyur Aravamudan V, Khan SR, Natarajan SK, Hussain I. The complex relationship between mesenteric panniculitis and malignancy - a holistic approach is still needed to understand the diagnostic uncertainties. Cureus. 2019;11:e5569.
  • Delgado Plasencia L, Rodríguez Ballester L, López-Tomassetti Fernández EM, Hernández Morales A, Carrillo Pallarés A, Hernández Siverio N. Mesenteric panniculitis: experience in our center. Rev Esp Enferm Dig. 2007;99:291-7.
  • Durst AL, Freund H, Rosenmann E, Birnbaum D. Mesenteric panniculitis: review of the leterature and presentation of cases. Surgery. 1977;81:203-11.
  • Patel N, Saleeb SF, Teplick SK. General case of the day. Mesenteric panniculitis with extensive inflammatory involvement of the peritoneum and intraperitoneal structures. Radiographics. 1999;19:1083-5.
  • Karmali RJ, Suami H, Wood CG, Karam JA. Lymphatic drainage in renal cell carcinoma: back to the basics. BJU Int. 2014;114:806-17.
  • Agur AMR, Lee MJ, Anderson JE. Lymphatic drainage of suprarenal glands,
  • Agur AMR, Dalley AF. Grant's Atlas of Anatomy. Baltimore, Williams & Wilkins, 1991.
  • Russell PS, Hong J, Windsor JA, Itkin M, Phillips ARJ. Renal lymphatics: anatomy, physiology, and clinical implications. Front Physiol. 2019;10:251.
  • Goodwin WE, Kaufman JJ. The renal lymphatics. I. Review of some of the pertinent literature. Urol Surv. 1956;6:305-29
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Üroloji
Bölüm Araştırma Makalesi
Yazarlar

Mehmet Eren Öztürk 0009-0001-1209-7036

Şevket Kahraman 0000-0001-6850-3569

Ahmet Yalçın 0000-0002-9708-0988

Mukadder Sunar 0000-0002-6744-3848

Gönderilme Tarihi 24 Temmuz 2025
Kabul Tarihi 5 Aralık 2025
Yayımlanma Tarihi 22 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 50 Sayı: 4

Kaynak Göster

MLA Öztürk, Mehmet Eren vd. “Prevalence and clinical correlates of mesenteric panniculitis in urinary stone disease”. Cukurova Medical Journal, c. 50, sy. 4, 2025, ss. 1084-91, doi:10.17826/cumj.1749647.