Impact of brief structured psychoeducation on quality of life, medication adherence, and health anxiety in euthymic patients with bipolar disorder

Caner Yeşiloğlu; Lut Tamam; Mehmet Emin Demirkol; Tugrul Demireğen; Cennet Yaren Sarıoğlu; Ömer Fettahlıoğlu; Damla Altın

doi:10.17826/cumj.1803773

TR EN

Kısa süreli yapılandırılmış psikoeğitimin, bipolar bozukluğu olan ötimik hastaların yaşam kalitesi, ilaç uyumu ve sağlık anksiyetesi üzerindeki etkisi

Öz

Amaç: Bu çalışma, bipolar bozukluk tanılı bireylerde psikoeğitimin yaşam kalitesi, işlevsellik, ilaç uyumu, sağlık anksiyetesi ve uyku üzerindeki etkilerini incelemeyi amaçlamıştır. Gereç ve Yöntem: DSM-5 kriterlerine göre bipolar bozukluk tanısı almış ve remisyonda bulunan toplam 25 birey, prospektif olarak takip edilmiştir. Uygun katılımcılar 18–65 yaş aralığında ötimik olup en az bir yıldır sabit ilaç tedavisi almaktaydı. Değerlendirmelerde Sosyodemografik Veri Formu, Global Değerlendirme Ölçeği (GDÖ), Dünya Sağlık Örgütü Yaşam Kalitesi Ölçeği Kısa Formu (WHOQOL-BREF), Pittsburgh Uyku Kalitesi İndeksi (PUKİ), Algılanan Sosyal Destek Çok Boyutlu Ölçeği (MSPSS), Bipolar Bozuklukta İşlevsellik Ölçeği (BBİÖ), Morisky İlaç Uyumu Ölçeği (MİUÖ) ve Kısa Sağlık Anksiyetesi Envanteri (KSAE) kullanılmıştır. Bulgular: Katılımcıların %68’i kadın (n=17), %32’si erkekti (n=8). Ortalama yaş 40,4 ± 13,2 yıl, tanı yaşı 27,2 ± 7,3 yıl bulundu. Psikoeğitim sonrası WHOQOL-BREF (52,05’ten 60,80’e) ve GDÖ (74,18’den 83,40’a) puanları anlamlı arttı. KSAE puanları azaldı (18,50’den 15,73’e). İlaç uyumu %48’den %100’e yükseldi. Bilgi testi puanları arttı (83,18’den 89,55’e). Sonuç: Psikoeğitim, bipolar bozukluk tanılı bireylerde yaşam kalitesini ve ilaç uyumunu artırmış, sağlık anksiyetesini azaltmıştır. Kısa süreli psikoeğitim programındanelde edilen bulgular bu yapılandırılmış yaklaşımın tedaviye uyumu güçlendirerek bireylerin genel iyilik haline katkı sağlayabileceğini göstermektedir.

Anahtar Kelimeler

Bipolar bozukluk , psikoeğitim , yaşam kalitesi , ilaç uyumu , sağlık anksiyetesi

Impact of brief structured psychoeducation on quality of life, medication adherence, and health anxiety in euthymic patients with bipolar disorder

Abstract

Purpose: This study aimed to examine the effects of psychoeducation on quality of life, functionality, medication adherence, health anxiety, and sleep quality in individuals diagnosed with bipolar disorder. Material and Methods: A total of 25 individuals diagnosed with bipolar disorder according to DSM-5 criteria and in remission were prospectively followed. Eligible participants were between 18 and 65 years old and had been on a stable medication regimen and euthymic for at least one year. The Sociodemographic Data Form, Global Assessment Scale (GAS), World Health Organization Quality of Life-BREF (WHOQOL-BREF), Pittsburgh Sleep Quality Index (PSQI), Multidimensional Scale of Perceived Social Support (MSPSS), Functioning Assessment Short Test for Bipolar Disorder (FAST), Morisky Medication Adherence Scale (MMAS), and Short Health Anxiety Inventory (SHAI) were administered. Results: Of the participants, 68% were female (n=17) and 32% male (n=8), with a mean age of 40.4 ± 13.2 years and mean age at diagnosis of 27.2 ± 7.3 years. After psychoeducation, WHOQOL-BREF scores (from 52.05 to 60.80) and GAS scores (from 74.18 to 83.40) significantly increased, while SHAI scores decreased (from 18.50 to 15.73). Medication adherence improved from 48% to 100%. Knowledge test scores significantly improved (from 83.18 to 89.55). Conclusion: Psychoeducation improved quality of life and medication adherence while reducing health anxiety in individuals with bipolar disorder. These findings suggest that brief, structured psychoeducation may positively influence treatment adherence and overall well-being.

Keywords

Bipolar disorder , psychoeducation , quality of life , medication adherence , health anxiety

Kaynakça

Gitlin MJ, Swendsen J, Heller TL, Hammen C. Relapse and impairment in bipolar disorder. Am J Psychiatry. 1995;152:1635-40.
Torrent C, Martinez-Arán A, Bonnin C del M et al. Long-term outcome of cognitive impairment in bipolar disorder. J Clin Psychiatry. 2012;73:e899-905.
Khafif TC, Belizario GO, Silva M, Gomes BC, Lafer B. Quality of life and clinical outcomes in bipolar disorder: an 8-year longitudinal study. J Affect Disord. 2021;278:239-43.
Vieta E, Torrent C. Functional remediation: the pathway from remission to recovery in bipolar disorder. World Psychiatry. 2016;15:288-89.
Karaytuğ MO, Tamam L, Demirkol ME, Namlı Z. Bipolar bozukluk tanılı hastalarda tedaviye uyum ve ilişkili faktörler. Arşiv Kaynak Tarama Dergisi. 2022;31:21-7.
Rabelo JL, Cruz BF, Ferreira JDR, Viana BM, Barbosa IG. Psychoeducation in bipolar disorder: a systematic review. World J Psychiatry. 2021;11:1407-24.
Levrat V, Favre S, Richard-Lepouriel H. Current practices of psychoeducation interventions with persons with bipolar disorders: a literature review. Front Psychiatry. 2024;14:1320654.
Pakpour AH, Modabbernia A, Lin CY, Saffari M, Ahmadzad Asl M, Webb TL. Promoting medication adherence among patients with bipolar disorder: a multicenter randomized controlled trial of a multifaceted intervention. Psychol Med. 2017;47:2528-39.
Couillard Larocque M, Fortin-Vidah G, Angers M, et al. Anxiety in bipolar disorder: a review of publication trends. J Affect Disord. 2023;320:340-47.
Vangal KK, Soman S, Bhandary RP, Praharaj SK. Sleep quality and quality of life in remitted bipolar disorder patients: a cross-sectional comparative study. Indian J Psychol Med. 2024;47:356-61.

Gold AK, Sylvia LG. The role of sleep in bipolar disorder. Nat Sci Sleep. 2016;8:207-14.
Eker F, Harkın S. Effectiveness of six-week psychoeducation program on adherence of patients with bipolar affective disorder. J Affect Disord. 2012;138:409-16.
Aydemir Ö, Uykur B, Akdeniz F. Reliability and validity of the Turkish version of the Bipolar Disorder Functioning Questionnaire. Turk Psikiyatri Derg. 2007;18:344-51.
Zimet GD, Dahlem NW, Zimet SG, Farley GK. The Multidimensional Scale of Perceived Social Support. J Pers Assess. 1988;52:30-41.
Stanley MA, Beck JG, Zebb BJ. Psychometric properties of the MSPSS in older adults. Aging Ment Health. 1998;2:186-93.
Eker D, Arkar H, Yaldız H. Çok Boyutlu Algılanan Sosyal Destek Ölçeği’nin gözden geçirilmiş formunun faktör yapısı, geçerlik ve güvenirliği. Turk Psikiyatri Derg. 2001;12:17-25.
Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28:193-213.
Ağargün MY, Kara H, Anlar Ö. Pittsburgh Uyku Kalitesi İndeksi’nin geçerliği ve güvenirliği. Türk Psikiyatri Derg. 1996;7:107-15.
Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24:67-74.
Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens (Greenwich). 2008;10:348-54.
Bahar A, Savaş HA, Bahar G, Demirtaş H. Morisky İlaç Tedavisine Uyum Ölçeği’nin Türkçe geçerlik ve güvenirliği. Anadolu Psikiyatri Derg. 2014;15:214-19.
Salkovskis PM, Rimes KA, Warwick HMC, Clark DM. The Health Anxiety Inventory: development and validation of scales for the measurement of health anxiety and hypochondriasis. Psychol Med. 2002;32:843-53.
Alberts NM, Hadjistavropoulos HD, Jones SL, Sharpe D. The Short Health Anxiety Inventory: a systematic review and meta-analysis. J Anxiety Disord. 2013;27:68-78.
Aydemir Ö, Kırpınar İ, Satı T, Uykur B, Cengisiz C. Sağlık Anksiyetesi Ölçeği’nin Türkçe için güvenilirlik ve geçerlilik çalışması. Nöro Psikiyatr Arş. 2013;50:325-31.
The WHOQOL Group. Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychol Med. 1998;28:551-58.
Skevington SM, Lotfy M, O’Connell KA; WHOQOL Group. The World Health Organization’s WHOQOL-BREF quality of life assessment: psychometric properties and results of the international field trial. Qual Life Res. 2004;13:299-310.
Eser E, Fidaner H, Fidaner C, Eser SY, Elbi H, Göker E. WHOQOL-BREF’in psikometrik özellikleri ve birinci sonuçları. Psikiyatri Psikoloji Psikofarmakoloji Derg. 1999;7:23-40.
Endicott J, Spitzer RL, Fleiss JL, Cohen J. The Global Assessment Scale: a procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry. 1976;33:766-71.
Piersma HL, Boes JL. An evaluation of the Global Assessment of Functioning Scale in two samples of psychiatric inpatients. Psychol Rep. 1997;80:639-47.
Aydemir Ö, Köroğlu E. Psikiyatride Kullanılan Klinik Ölçekler. Ankara, Hekimler Yayın Birliği, 2000.
Bonnín CDM, Reinares M, Martínez-Arán A, et al. Improving functioning, quality of life, and well-being in patients with bipolar disorder. Int J Neuropsychopharmacol. 2019;22:467-77.
Mannapperuma U, Galappatthy P, Jayakody RL, Mendis J, de Silva VA, Hanwella R. Safety monitoring of treatment in bipolar disorder in a tertiary care setting in Sri Lanka and recommendations for improved monitoring in resource limited settings. BMC Psychiatry. 2019;19:194.
Kazan Kizilkurt O, Giynas FE, Yazici Gulec M, Gulec H. Bipolar disorder and perceived social support: relation with clinical course, and the role of suicidal behaviour. Psychiatry Clin Psychopharmacol. 2019;29:787-93.
Nabavi B, Mitchell AJ, Nutt D. A lifetime prevalence of comorbidity between bipolar affective disorder and anxiety disorders: a meta-analysis of 52 interview-based studies of psychiatric population. EBioMedicine. 2015;2:1405-19.
Lebel S, Mutsaers B, Tomei C et al. Health anxiety and illness-related fears across diverse chronic illnesses: a systematic review on conceptualization, measurement, prevalence, course, and correlates. PLoS One. 2020;15:e0234124.
Gumus F, Buzlu S, Cakir S. Effectiveness of individual psychoeducation on recurrence in bipolar disorder; a controlled study. Archives of Psychiatric Nursing. 2015;29:174-79.
Parikh SV, Zaretsky A, Beaulieu S et al. A randomized controlled trial of psychoeducation or cognitive-behavioral therapy in bipolar disorder: A Canadian Network for Mood and Anxiety Treatments (CANMAT) study. J Clin Psychiatry. 2013;74:440–46.
Colom F, Vieta E, Sánchez-Moreno J et al. Group psychoeducation for stabilised bipolar disorders: five-year outcome of a randomised clinical trial. Br J Psychiatry. 2009;194:260–65.
Okazaki T, Nakatsu K, Asaoka S et al. Factors associated with long-term medication adherence in patients who participated in a short-term group psychoeducation program for bipolar disorder. J Psychosoc Rehabil Ment Health. 2023;10:123–32.
Petzold J, Mayer-Pelinski R, Pilhatsch M et al. Short group psychoeducation followed by daily electronic self-monitoring in the long-term treatment of bipolar disorders: a multicenter, rater-blind, randomized study. Int J Bipolar Disord. 2019;7:25.
Jones S, Deville M, Mayes D, Lobban F. Self-management in bipolar disorder: the story so far. J Ment Health. 2011;20:583–92.
Michalak EE, Morton E, Barnes SJ, Hole R et al. Supporting self-management in bipolar disorder: mixed-methods knowledge translation study. JMIR Ment Health. 2019;6:e13493.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Psikiyatri

Bölüm

Araştırma Makalesi

Yazarlar

Caner Yeşiloğlu ^*
0000-0002-9997-351X
Türkiye

Lut Tamam
0000-0002-9750-7531
Türkiye

Mehmet Emin Demirkol
0000-0003-3965-7360
Türkiye

Tugrul Demireğen
0000-0002-7633-3974
Türkiye

Cennet Yaren Sarıoğlu
0009-0002-8957-423X
Türkiye

Ömer Fettahlıoğlu
0009-0008-6591-8783
Türkiye

Damla Altın
0009-0008-6483-4801
Türkiye

Yayımlanma Tarihi

22 Aralık 2025

Gönderilme Tarihi

15 Ekim 2025

Kabul Tarihi

3 Aralık 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 50 Sayı: 4

DOI

https://doi.org/10.17826/cumj.1803773

IZ

https://izlik.org/JA84TT73JS

MLA

Yeşiloğlu, Caner, vd. “Impact of brief structured psychoeducation on quality of life, medication adherence, and health anxiety in euthymic patients with bipolar disorder”. Cukurova Medical Journal, c. 50, sy 4, Aralık 2025, ss. 1103-1, doi:10.17826/cumj.1803773.

Bu eser Creative Commons Atıf-Gayriticari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Kısa süreli yapılandırılmış psikoeğitimin, bipolar bozukluğu olan ötimik hastaların yaşam kalitesi, ilaç uyumu ve sağlık anksiyetesi üzerindeki etkisi

Öz

Anahtar Kelimeler

Impact of brief structured psychoeducation on quality of life, medication adherence, and health anxiety in euthymic patients with bipolar disorder

Abstract

Keywords

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster