Methotrexate-associated sexual dysfunction in a female patient with rheumatoid arthritis
Abstract
Methotrexate(MTX) is widely used in rheumatology practice for rheumatoid arthritis and many other conditions, including psoriatic arthritis, autoimmune connective tissue diseases, sarcoidosis, and vasculitis. The most common adverse effects of MTX include nausea, fatigue, dizziness, headache, stomatitis and abdominal pain. Serious adverse effects include hepatotoxicity, pulmonary toxicity, nephrotoxicity, myelosuppression and increased risk of lymphoproliferative disorders. In our review of the literature, case reports of sexual dysfunction have beeen reported during MTX therapy. We report here one case of sexual dysfunction during MTX therapy.
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