Evaluation of frontal QRS-T angle and cardiac electrophysiological balance index in patients with coronary artery ectasia

Yıl 2025, Cilt: 50 Sayı: 4, 1145 - 1152, 22.12.2025

Pınar Özmen Yıldız

https://doi.org/10.17826/cumj.1832176

https://izlik.org/JA79ZE52GP

Öz

urpose: The aim of this study was to evaluate arrhythmogenic risk in patients with Coronary artery ectasia (CAE) using the frontal QRS-T (fQRS-T) angle and the index of cardiac electrophysiological balance (iCEB), together with conventional ventricular repolarization parameters.
Materials and Methods: This retrospective study included 103 patients who underwent coronary angiography. Individuals with coronary segment dilatation ≥1.5 times the adjacent normal vessel without significant stenosis were classified as the CAE group, while those with angiographically normal coronary arteries comprised the control group. Electrocardiographic (ECG) parameters were analyzed: QT and corrected QT (QTc) intervals, T wave peak-to-end (Tp-e) interval, Tp-e/QT and Tp-e/QTc ratios, fQRS-T angle, and iCEB calculated as QT/QRS; its corrected form (iCEBc) was computed as QTc/QRS. Subgroup analysis compared single-vessel and multivessel ectasia.
Results: Patients with CAE demonstrated significantly wider fQRS-T angles (68.0° vs. 22.0°) and higher iCEB (4.39 vs. 4.04) and iCEBc values (4.82 vs. 4.43) compared with controls. QT, QTc, Tp-e, Tp-e/QT, and Tp-e/QTc values were also significantly increased. Multivessel ectasia was associated with a significantly greater fQRS-T angle (84.0° vs. 48.5°) and QTc prolongation (446.6 vs. 414.6 ms).
Conclusion: CAE is associated with substantial electrophysiological alterations indicative of heightened arrhythmogenic susceptibility. Increasing anatomical extent further amplifies this burden, particularly as reflected by a wider fQRS-T angle and the global repolarization burden demonstrated by prolonged QTc.

Anahtar Kelimeler

Coronary ectasia , electrocardiography , ischemia , repolarization

Etik Beyan

The present study protocol was reviewed and approved by the institutional review board of Health Sciences University, Adana City Training and Research Hospital (Reg. No. 19/863, Date: 20.11.2025).

Destekleyen Kurum

None

Teşekkür

None

Koroner arter ektazisi olan hastalarda frontal QRS-T açısı ve kardiyak elektrofizyolojik denge indeksinin değerlendirilmesi

https://izlik.org/JA79ZE52GP

Öz

Amaç: Bu çalışma, koroner arter ektazisili (CAE)hastalarda aritmojenik riski; frontal QRS-T (fQRS-T) açısı ve kardiyak elektrofizyolojik denge indeksi (iCEB) ile birlikte konvansiyonel ventriküler repolarizasyon parametrelerini değerlendirerek belirlemeyi amaçlamıştır.
Gereç ve Yöntem: Bu retrospektif çalışma, koroner anjiyografi uygulanan 103 hastayı içermektedir. Komşu normal segmentin çapının ≥1.5 katı düzeyinde, anlamlı stenoz olmaksızın koroner arter dilatasyonu bulunan bireyler CAE grubu olarak sınıflandırılırken; anjiyografik olarak normal koroner arterlere sahip hastalar kontrol grubunu oluşturmuştur. Elektrokardiyografik (EKG) parametreler değerlendirilmiştir: QT ve düzeltilmiş QT (QTc) aralıkları, T dalgası pikten sonuna kadar olan süre (Tp-e), Tp-e/QT ve Tp-e/QTc oranları, fQRS-T açısı ve QT/QRS olarak hesaplanan iCEB; düzeltilmiş formu (iCEBc) QTc/QRS olarak hesaplanmıştır. Alt grup analizinde tek damar ve çok damar ektazisi karşılaştırılmıştır.
Bulgular: CAE’li hastalarda fQRS-T açısı kontrol grubuna kıyasla anlamlı derecede daha geniş bulunmuştur (68.0° karşı 22.0°) ve iCEB (4.39 karşı 4.04) ile iCEBc (4.82 karşı 4.43) değerleri de daha yüksektir. Ayrıca QT, QTc, Tp-e, Tp-e/QT ve Tp-e/QTc değerleri anlamlı şekilde artmıştır. Çok damar ektazisi olan hastalarda fQRS-T açısı anlamlı olarak daha geniştir (84.0° karşı 48.5°) ve QTc daha uzundur (446.6 karşı 414.6 ms).
Sonuç: CAE, artmış aritmojenik yatkınlığı yansıtan belirgin elektrofizyolojik değişikliklerle ilişkilidir. Ektazinin anatomik yaygınlığındaki artış bu yükü daha da artırmakta olup, özellikle fQRS-T açısının belirgin genişlemesi ve QTc uzamasında görülmektedir.

Anahtar Kelimeler

Koroner ektazi , elektrokardiyografi , iskemi , repolarizasyon

Etik Beyan

Bu çalışma protokolü, Sağlık Bilimleri Üniversitesi Adana Şehir Eğitim ve Araştırma Hastanesi Kurumsal Etik Kurulu tarafından incelenmiş ve onaylanmıştır (Kayıt No: 19/863, Tarih: 20.11.2025).

Destekleyen Kurum

Yoktur

Teşekkür

Yoktur

Kaynakça

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