Evaluation of frontal QRS-T angle and cardiac electrophysiological balance index in patients with coronary artery ectasia
Öz
urpose: The aim of this study was to evaluate arrhythmogenic risk in patients with Coronary artery ectasia (CAE) using the frontal QRS-T (fQRS-T) angle and the index of cardiac electrophysiological balance (iCEB), together with conventional ventricular repolarization parameters.
Materials and Methods: This retrospective study included 103 patients who underwent coronary angiography. Individuals with coronary segment dilatation ≥1.5 times the adjacent normal vessel without significant stenosis were classified as the CAE group, while those with angiographically normal coronary arteries comprised the control group. Electrocardiographic (ECG) parameters were analyzed: QT and corrected QT (QTc) intervals, T wave peak-to-end (Tp-e) interval, Tp-e/QT and Tp-e/QTc ratios, fQRS-T angle, and iCEB calculated as QT/QRS; its corrected form (iCEBc) was computed as QTc/QRS. Subgroup analysis compared single-vessel and multivessel ectasia.
Results: Patients with CAE demonstrated significantly wider fQRS-T angles (68.0° vs. 22.0°) and higher iCEB (4.39 vs. 4.04) and iCEBc values (4.82 vs. 4.43) compared with controls. QT, QTc, Tp-e, Tp-e/QT, and Tp-e/QTc values were also significantly increased. Multivessel ectasia was associated with a significantly greater fQRS-T angle (84.0° vs. 48.5°) and QTc prolongation (446.6 vs. 414.6 ms).
Conclusion: CAE is associated with substantial electrophysiological alterations indicative of heightened arrhythmogenic susceptibility. Increasing anatomical extent further amplifies this burden, particularly as reflected by a wider fQRS-T angle and the global repolarization burden demonstrated by prolonged QTc.
Anahtar Kelimeler
Coronary ectasia, electrocardiography, ischemia, repolarization
Destekleyen Kurum
Yoktur
Etik Beyan
Bu çalışma protokolü, Sağlık Bilimleri Üniversitesi Adana Şehir Eğitim ve Araştırma Hastanesi Kurumsal Etik Kurulu tarafından incelenmiş ve onaylanmıştır (Kayıt No: 19/863, Tarih: 20.11.2025).
Teşekkür
Yoktur
Kaynakça
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