Düzeltme: Corrigendum [Effect of bromelain on apoptotic and inflammatory pathways in cyclophosphamide-induced hepatotoxicity]
Düzeltme Notu
Öz
In the article published in the Cukurova Medical Journal, 2026;51(2):639-647, the following corrections have been made at the request of the authors:
In the Materials and Methods section of the Abstract, the word “kidney” has been corrected to “liver.”
In the Gereç ve Yöntem section of the Öz, the word “böbrek” has been corrected to “karaciğer.”
In the Approval Number section of the Materials and Methods, the year “2004” has been corrected to “2024.”.
The ethics statement is now as follows “Ethics approval of the current study was granted by the animal experiments local ethical committee of Harran University (HRU) (Date; 24.12.2024/Approval number; 2024-008/01-10).”
The corrections have been incorporated into the updated version of the article.
Anahtar Kelimeler
Cyclophosphamide, Bromelain, Liver, Inflammatory response, Caspase-3, TNF-α, TLR-4/NF-κB pathway
Kaynakça
- Zhong H, Lai Y, Zhang R, Daoud A, Feng Q, Zhou J et al. Low dose cyclophosphamide modulates tumor microenvironment by TGF-β signaling pathway. Int J Mol Sci. 2020;21:957.
- Heidari-Soreshjani S, Asadi-Samani M, Yang Q, Saeedi-Boroujeni A. Phytotherapy of nephrotoxicity-induced by cancer drugs: an updated review. J Nephropathol. 2017;6:254-63.
- Abdallah AN, Effat H, Mousbah AM, Ahmed HH, Abohashem RS. Cyclophosphamide: Potential hepatorenal toxicity and the possible therapeutic role of mesenchymal stem cell‐derived exosomes in wistar rats. J Biochem Mol Toxicol. 2026;40:e70705.
- Mahipal P, Pawar RS. Nephroprotective effect of Murraya koenigii on cyclophosphamide induced nephrotoxicity in rats. Asian Pac J Trop Med. 2017;10:808-12.
- Singh C, Prakash C, Tiwari KN, Mishra SK, Kumar V. Premna integrifolia ameliorates cyclophosphamide-induced hepatotoxicity by modulation of oxidative stress and apoptosis. Biomed Pharmacother. 2018;107:634-43.
- Van Den Boogaard, WMC, Komninos DSJ, Vermeij WP. Chemotherapy side-effects: not all DNA damage is equal. Cancers. 2022;14:627.
- Fouad A, Qutub H O, Al-Melhim WN. Punicalagin alleviates hepatotoxicity in rats challenged with cyclophosphamide. Environ Toxicol Pharmacol. 2016;45:158-62.
- Mahmoud AM, Germoush MO, Alotaibi MF, Hussein OE. Possible involvement of Nrf2 and PPARγ up-regulation in the protectiveeffect of umbelliferone against cyclophosphamide-induced hepatotoxicity. Biomed Pharmacother. 2017;86:297-306.
- Manzoor Z, Nawaz A, Mukhtar H, Haq I. Bromelain: Methods of extraction, purification and therapeutic applications. Braz Arch Biol Technol. 2016;59:e16150010.
- Chobotova K, Vernallis AB, Majid FAA. Bromelain'sactivity and potential as an anti-cancer agent: current evidenceand perspectives. Cancer Lett. 2010;290:148–56
