Evaluation of relationship between body-mass index and spermiogram parameters in subfertile males
Öz
Purpose: The aim of this study was to evaluate the relationship between body-mass index and spermiogram parameters in subfertile maleparameters in male partner of the infertile couples.
Material and Methods: The study was conducted in Infertility Research and Treatment Center of a University Hospital. Hospital records of male partner of 102 infertile couple was considered and patients who had factors possibly had a negative effect on the results of the sperm analysis as chemical agent exposure and systemic disease were excluded, and a total of 94 patients included in the study after this evaluation. These 94 patients were divided in two groups (body-mass index ≤25 and body-mass index >25) and results of the sperm analysis were compared between two groups as primary out-come of the study. These 94 patients were divided in two groups (body-mass index ≤30 and body-mass index >30) and results of the sperm analysis were compared as secondary out-come of the study.
Results: The mean age (±standart deviation) of the 94 cases included in the study was 34.44±5.58. Distribution of the basal demographic characteristics of the cases according to the body-mass index were similar. Results of the statistical analysis based on the cut-off values of overweight (>25) and obese (>30) were similar in terms of volum, likefaction, total sperm count and total motile sperm count.
Conclusion: There was no relationship between body-mass index and sperm parameters calculating by conventional sperm analysis.
Anahtar Kelimeler
Kaynakça
- Taylor A. ABC of subfertility: extent of the problem. Br Med J. 2003;327:434-36.
- Pasquali R, Patton L, Gambineri A. Obesity and infertility. Curr Opin Endocrinol Diabetes Obes. 2007;14:482-7.
- Maheshwari A, Stofberg L, Bhattacharya S. Effect of overweight and obesity on assisted reproductive technology—a systematic review. Hum Reprod Update. 2007;13:433-44.
- Hammoud AO, Wilde N, Gibson M, Parks A, Carrell DT, Meikle AW. Male obesity and alteration in sperm parameters. Fertil Steril. 2008;90:2222-5.
- MacDonald AA, Herbison GP, Showell M, Farquhar CM. The impact of body mass index on semen parameters and reproductive hormones in human males: a systematic review with meta-analysis. Hum Reprod Update. 2010;16:293-311.
- Sermondade N, Faure C, Fezeu L, Shayeb AG, Bonde JP, Jensen TK, et al. BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis. Hum Reprod Update. 2013;19:221-31.
- Thomsen L, Humaidan P, Bungum L, Bungum M. The impact of male overweight on semen quality and outcome of assisted reproduction. Asian J Androl. 2014;16:749-54.
- Fernandez CD, Bellentani FF, Fernandes GS, Perobelli JE, Favareto AP, Nascimento AF et al. Diet-induced obesity in rats leads to a decrease in sperm motility. Reprod Biol Endocrinol. 2011;9:32.
- Duale N, Steffensen IL, Andersen J, Brevik A, Brunborg G, Lindeman B. Impaired sperm chromatin integrity in obese mice. Andrology. 2014;2:234-43.
- Palmer NO, Fullston T, Mitchell M, Setchell BP, Lane M. SIRT6 in mouse spermatogenesis is modulated by diet-induced obesity. Reprod Fertil Dev. 2011;23:929-39.
