Postoperative severe hypertension in a patient with acromegaly
Abstract
Acromegaly is a chronic disorder characterized by excessive secretion of growth hormone and elevated insulin-like growth factor-1 levels, usually due to a pituitary adenoma. In this patients, hypertension occurs in 18-60%, with a predominance of diastolic blood pressure elevation that increases in prevalence with age. Hypertension is likely due to increased plasma volume, to decreased ANP levels and to insulin resistance and disease duration are coexisting factors likely to increase the risk of hypertension. In this article, we report a case of a female patient with postoperative severe hypertension who presented with acromegaly secondary to a pituitary microadenoma.
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