Kronik hastalıklar ekseninde diyette yüksek fruktoz ve doymuş yağ asitlerinin kronik düşük derece inflamasyon üzerine etkisi

Mahmut Bodur; Reyhan Nergiz Ünal

doi:10.17826/cumj.482623

TR EN

Kronik hastalıklar ekseninde diyette yüksek fruktoz ve doymuş yağ asitlerinin kronik düşük derece inflamasyon üzerine etkisi

Öz

Son yıllarda kronik hastalıkların ortaya çıkmasında, kronik düşük derece inflamasyonun rolü üzerinde durulmaktadır. Kronik düşük derece inflamasyon, sistemik dolaşım ve çeşitli dokularda inflamatuvar medyatörlerin ve bazı proinflamatuvar sitokinlerin artışı ile karakterize olan metabolik bir süreçtir. C reaktif protein (CRP), tümör nekrozis faktör-α (TNF-α), interlökin-1 (IL-1), interlökin-4 (IL-4), interlökin-6 (IL-6), toll benzeri reseptör-4 (TLR-4) kronik düşük derece inflamasyonda rol oynayan bazı proinflamatuvar moleküllerdir. Güncel çalışmalarda, hazır ve işlenmiş besinlerin tüketimiyle artan fruktoz ve doymuş yağ asitleri alımının kronik düşük derece inflamasyon oluşumunda etkileri olduğu gösterilmektedir. Bu derlemede, diyetle yüksek fruktoz ve doymuş yağ asitleri alımının, proinflamatuvar medyatörler aracılığıyla kronik düşük derece inflamasyon oluşumuna etkisi incelenmiştir.

Anahtar Kelimeler

doymuş yağ asitleri,fruktoz,inflamasyon,proinflamatuvar moleküller

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Sağlık Kurumları Yönetimi

Bölüm

Derleme

Yazarlar

Mahmut Bodur
0000-0002-2105-8485
Türkiye

Reyhan Nergiz Ünal ^*
0000-0002-3143-7710
Türkiye

Yayımlanma Tarihi

30 Haziran 2019

Gönderilme Tarihi

14 Kasım 2018

Kabul Tarihi

13 Ocak 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 44 Sayı: 2

DOI

https://doi.org/10.17826/cumj.482623

IZ

https://izlik.org/JA49BK84BS

MLA

Bodur, Mahmut, ve Reyhan Nergiz Ünal. “Kronik hastalıklar ekseninde diyette yüksek fruktoz ve doymuş yağ asitlerinin kronik düşük derece inflamasyon üzerine etkisi”. Cukurova Medical Journal, c. 44, sy 2, Haziran 2019, ss. 685-94, doi:10.17826/cumj.482623.