Araştırma Makalesi

Evaluation of simultaneous blood and cerebrospinal fluid culture findings in neonatal meningitis

Cilt: 44 Sayı: 3 30 Eylül 2019
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Evaluation of simultaneous blood and cerebrospinal fluid culture findings in neonatal meningitis

Abstract

Purpose: The aim of our present study was to investigate the simultaneous findings of both blood and cerebrospinal fluid cultures and to determine the etiological pathogens responsible for neonatal sepsis and meningitis in our neonatal intensive care unit.

Materials and Methods: This study was carried out in our newborn department from November 2013 to October 2015. During this period 732 neonates with signs and symptoms of neonatal sepsis were included in our study. Sepsis and meningitis work up were performed and simultaneous blood and cerebrospinal fluid cultures were taken from eligible patients.

Results: Cerebrospinal fluid cultures were positive in100 (13.7%) of cases. Positive blood cultures were found in 59 (8.1%) neonates with meningitis. Staphylococcus bacteria (48%) was the most frequent organism responsible for confirmed meningitis, followed by klebsiella (19%) and pseudomonas (10%). Simultaneous pathogens isolated from blood cultures were Staphylococcus (%24), klebsiella (13%) and pseudomonas (8%).

Conclusion: In our study group staphylococcus, klebsiella and pseudomonas were the main etiological agents that were responsible for  neonatal sepsis and  meningitis in our unit.


Keywords

Blood culture,cerebrospinal fluid culture,neonatal meningitis,sepsis

Kaynakça

  1. 1. Ku LC, Bogges KA, Cohen-Wolkowiez M. Bacterial meningitis in the infant. Clin Perinatol. 2015;42:29-45.
  2. 2. Heath PT, Okike IO, Oeser C. Neonatal meningitis: can we do better? Adv Exp Med Biol. 2011;719:11–24.
  3. 3. Shane AL, Stoll BJ. Recent developments and current issues in the epidemiology, diagnosis, and management of bacterial and fungal neonatal sepsis. Am J Perinatol. 2013;30:131–41.
  4. 4. Fanaroff AA, Korones SB, Wright LL, Verter J, Poland RL, Bauer CR et al. Incidence, presenting features, risk factors and significance of late onset septicemia in very low birth weight infants. The National Institute of Child Health and Human Development Neonatal Research Network. Pediatr Infect Dis J. 1998;17:593–8.
  5. 5. Furyk JS, Swann O, Molyneux E. Systematic review: neonatal meningitis in the developing world. Trop Med Int Health. 2011;16:672–9.
  6. 6. Heath PT, Okike IO. Neonatal bacterial meningitis: an update. Paediatrics Child Health. 2010;20:526–530.
  7. 7. Thaver D, Zaidi AK. Burden of neonatal infections in developing countries: a review of evidence from community-based studies. Pediatr Infect Dis J. 2009;28:3–9.
  8. 8. Stoll BJ, Hansen N, Fanaroff AA et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics. 2002;110:285–91.
  9. 9. Cohen-Wolkowiez M, Moran C, Benjamin DK et al. Early and late onset sepsis in late preterm infants. Pediatr Infect Dis J. 2009;28:1052–6.
  10. 10. Gaschignard J, Levy C, Romain O et al. Neonatal Bacterial Meningitis, 444 Cases in 7 Years. Pediatr Infect Dis J. 2011;30:212–7.

Kaynak Göster

MLA
Halil, Halit, vd. “Evaluation of simultaneous blood and cerebrospinal fluid culture findings in neonatal meningitis”. Cukurova Medical Journal, c. 44, sy 3, Eylül 2019, ss. 829-34, doi:10.17826/cumj.485624.