Faktör V Leiden Mutasyonu ve Lipoprotein A Yüksekliğinin Bir Arada Olduğu Genç Yaş Miyokard İnfarktüsü

Cilt: 38 Sayı: 3 1 Eylül 2013
Abdulmelik Yıldız , Bayram Bağırtan , İlgın Karaca
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A Young Aged Myocardial Infarction with Factor V Leiden Mutation and High Lipoprotein A Level

Abstract

Summary Factor V Leiden (FVL) mutation has been shown tendency to thrombosis. Lipoprotein a (Lpa) is thought to be proatherogenic and prothrombotic. There are several publications that were reported that FVL mutation might be responsible for myocardial infarction especially in a young age group. 33 year old male patient was admitted to the emergency room with chest pain. Acute anterior myocardial infarction was diagnosed with electrocardiography. Coronary Angiography was performed. Coronary Angiography showed that there was a total occlusion in the proximal part of the left anterior descending artery (LAD). Other coronary arteries were normal. Complete patency was achieved with direct stent procedures in the completely occluded part of the left anterior descending coronary artery. FVL heterozygous mutation was found with polymerase chain reaction method. Elevated Lpa was found in the same period. A control angiography was done 2 months after the stent application because of recurrent anginal attacks. In the control angiography, it was observed that stent was open.Key words:

Keywords

Factor V Leiden mutation, Lipoprotein a, Acute myocardial infarction

Kaynakça

  1. Price DT, Ridker PM. Factor V Leiden Mutation and the risk for thromboembolic disease: A clinical perspective. Ann. İnt. Med. 1997; 127:895-903.

Kaynak Göster

MLA
Yıldız, Abdulmelik, vd. “Faktör V Leiden Mutasyonu ve Lipoprotein A Yüksekliğinin Bir Arada Olduğu Genç Yaş Miyokard İnfarktüsü”. Cukurova Medical Journal, c. 38, sy 3, Eylül 2013, ss. 525-7, https://izlik.org/JA46DR55UF.