Investigation of the Effect of Deep Brain Stimulation Surgery on Mobility, Emotional Status and Quality of Life in a Patient with Dystonia: Case Repor
Öz
The aim of our study is to examine the effects of deep brain stimulation (DBS) surgery on severity of dystonia, mobility, emotional status, and health-related quality of life (QOL) in patient with dystonia. This study was carried out on a case of 41-year-old female with complaints of neck and arm pain, involuntary contraction for 30 years. GPİ-DBS was applied to the patient bilaterally in 2010. Global Dystonia Scale (GDS) was used to assess the severity of the patient's dystonia, effects on body parts and functions. Beck Depression Inventory (BDI) was applied to detect emotional status. 12- Meter Walking Test (mobility) and Short Form-36 (SF-36) were used to evaluate quality of life. All assessments were repeated prior to surgery, after surgery 1st year and 3rd years. Prior to surgery, GDS was 112. Postoperative 1st and 3rd years, GDS was respectively 69/84. Prior to surgery, the total BDI score was 31. Postoperative 1st and 3rd years, GDS was respectively 28/40. 12-Meter Walking Test results were respectively 18/10/15 sec. for the prior to surgery, postoperative 1st. and 3rd years. General health status and physical function subscales of SF-36, respectively, prior to surgery were 30/75, postoperative 1st year was 60/85 and 3rd years were 20/35. GPI-DBS is a surgical procedure, which has positive effect on mobility, emotional status and QOL, in patient with dystonia.
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- Vercueil L, Pollak P, Fraix V, Caputo E, Moro E, Benazzouz A, et al. Deep Brain Stimulation in the Treatment of Severe Dystonia. J Neurol. 2001;2:695– 700.
- Manji H, Howard RS, Miller DH, Hirsch NP, Carr L, Bahtia K, et al. Status Dystonicus: the Syndrome and its Management. Brain. 1998;121:243–52.
- Balash Y, Giladi N. Efficacy of Pharmacological Treatment of Dystonia: Evidence-Based Review Including Meta-analysis of the Effect of BTX and Other Cure Options. Eur J Neurol. 2004;11:361–70.
- Fahn S, Bressman SB, Marsden CD. Classification of dystonia. Adv Neurol. 1998;78:1-10.
- Fahn S. Concept and classification of dystonia. Adv Neurol. 1998;50:1–8.
- Vidailhet M, Vercueil L, Houeto JL, Houeto JL, Krystkowiak P, Benabid AL, et al. Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia. N Engl J Med. 2005;352:459– 67.
- Thobois S, Danaila T, Polo G, Simon E, Mertens P, Broussolle E. Deep-Brain Stimulation for Dystonia: Current Indications and Future Orientations. Future Neurology. 2014;9:77-87.
- Benabid AL, Benazzouz A, Hoffmann D, Limousin P, Krack P, Pollak P. Long-term electrical inhibition of deep brain targets in movement disorders. Mov Disord. 1998;13:119-25.
- Lozano AM, Abosch A. Pallidal stimulation for dystonia. Adv Neurol. 2004;94:301-8.
- Cif L, El Fertit H, Vayssiere N, Hemm S, Hardouin E, Gannau A, Tuffery S, Coubes P. Treatment of dystonic syndromes by chronic electrical stimulation of the internal globus pallidus. Neurosurg Sci. 2003;47:52-5.
